saralasin

出典: meddic

サララシン

saralasin acetate

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/29 15:09:02」(JST)

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英文文献

  • Bovine ovarian cells have (pro)renin receptors and prorenin induces resumption of meiosis in vitro.
  • Dau AM1, da Silva EP1, da Rosa PR1, Bastiani FT1, Gutierrez K1, Ilha GF1, Comim FV2, Gonçalves PB3.
  • Peptides.Peptides.2016 Jul;81:1-8. doi: 10.1016/j.peptides.2016.03.010. Epub 2016 Apr 6.
  • The discovery of a receptor that binds prorenin and renin in human endothelial and mesangial cells highlights the possible effect of renin-independent prorenin in the resumption of meiosis in oocytes that was postulated in the 1980s.This study aimed to identify the (pro)renin receptor in the ovary a
  • PMID 27060674
  • In vitro method of studying the angiotensin activity of chemical compounds.
  • Spasov AA1, Yakovlev DS, Bukatina TM, Brigadirova AA.
  • Bulletin of experimental biology and medicine.Bull Exp Biol Med.2014 Nov;158(1):115-7. doi: 10.1007/s10517-014-2705-8. Epub 2014 Nov 19.
  • We developed and tested an experimental model to study in vitro the type 1 angiotensin antagonistic activity of compounds on the isolated portal vein of rats. The reliability of this method was confirmed in tests with saralasin (nonselective antagonist of angiotensin receptors) and losartan (selecti
  • PMID 25403411
  • Saralasin and Sarile Are AT2 Receptor Agonists.
  • Guimond MO1, Hallberg M2, Gallo-Payet N1, Wallinder C3.
  • ACS medicinal chemistry letters.ACS Med Chem Lett.2014 Aug 18;5(10):1129-32. doi: 10.1021/ml500278g. eCollection 2014.
  • Saralasin and sarile, extensively studied over the past 40 years as angiotensin II (Ang II) receptor blockers, induce neurite outgrowth in a NG108-15 cell assay to a similar extent as the endogenous Ang II. In their undifferentiated state, these cells express mainly the AT2 receptor. The neurite out
  • PMID 25313325

和文文献

  • Saralasin, a Nonspecific Angiotensin II Receptor Antagonist, Attenuates Oxidative Stress and Tissue Injury in Cerulein-Induced Acute Pancreatitis
  • IP Siu Po,TSANG Siu Wai,WONG Tung Po,CHE Chun Tao,LEUNG Po Sing
  • Pancreas 26(3), 224-229, 2003-04-01
  • NAID 10016164414
  • Evidence for the AT_1 Subtype of the Angiotensin II Receptor in the Rat Submandibular Gland
  • , , [他], , , ,
  • Biological & pharmaceutical bulletin 23(10), 1185-1188, 2000-10-01
  • … Ang II, Ang III and saralasin completely displaced the [^3H]Ang II binding, whereas CV-11974,an AT_1 receptor antagonist and PD123319,an AT_2 receptor antagonist maximally displaced up to approximately 87 and 13% of the total binding, respectively. …
  • NAID 110003639851
  • Stretch-Induced Proliferation of Cultured Vascular Smooth Muscle Cells and a Possible Involvement of Local Renin-Angiotensin System and Platelet-Derived Growth Factor (PDGF)
  • LI Qing,MURAGAKI Yasuteru,UENO Hikaru,OOSHIMA Akira
  • Hypertension research : clinical and experimental : official journal of the Japanese Society of Hypertension 20(3), 217-223, 1997-09-01
  • NAID 10009562195

関連リンク

View and buy high purity Saralasin from Tocris Bioscience, the leading worldwide supplier of high performance life science reagents ... The technical data provided above is for guidance only. For batch specific data refer to the ...
saralasin [sar-al´ah-sin] an angiotensin II antagonist, used in the form of the acetate ester as an antihypertensive in treatment of severe hypertension and in diagnosis of renin-dependent hypertension. saralasin /sar·al·a·sin/ (sar-al´ah ...

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