WordNet

any of various organs that synthesize substances needed by the body and release it through ducts or directly into the bloodstream (同)secretory organ, secretor, secreter
a clear liquid secreted into the mouth by the salivary glands and mucous glands of the mouth; moistens the mouth and starts the digestion of starches (同)spit, spittle
the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect (同)endocrine, internal_secretion
of or relating to saliva; "salivary gland"

PrepTutorEJDIC

(生物体内の)腺(せん)
だ液,つば
ホルモン
だ液の;だ液を分泌する

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 悪性唾液腺腫瘍：再発性および転移性疾患の治療 malignant salivary gland tumors treatment of recurrent and metastatic disease
2. 甲状腺ホルモンに対する感受性の傷害 impaired sensitivity to thyroid hormone
3. 小児における成長ホルモン欠乏症の治療 treatment of growth hormone deficiency in children
4. 唾石症 salivary gland stones
5. 副甲状腺ホルモン測定およびその臨床応用 parathyroid hormone assays and their clinical use

English Journal

The sodium iodide symporter (NIS): Regulation and approaches to targeting for cancer therapeutics.

Kogai T, Brent GA.AbstractExpression of the sodium iodide symporter (NIS) is required for efficient iodide uptake in thyroid and lactating breast. Since most differentiated thyroid cancer expresses NIS, β-emitting radioactive iodide is routinely utilized to target remnant thyroid cancer and metastasis after total thyroidectomy. Stimulation of NIS expression by high levels of thyroid-stimulating hormone is necessary to achieve radioiodide uptake into thyroid cancer that is sufficient for therapy. The majority of breast cancer also expresses NIS, but at a low level insufficient for radioiodine therapy. Retinoic acid is a potent NIS inducer in some breast cancer cells. NIS is also modestly expressed in some non-thyroidal tissues, including salivary glands, lacrimal glands and stomach. Selective induction of iodide uptake is required to target tumors with radioiodide. Iodide uptake in mammalian cells is dependent on the level of NIS gene expression, but also successful translocation of NIS to the cell membrane and correct insertion. The regulatory mechanisms of NIS expression and membrane insertion are regulated by signal transduction pathways that differ by tissue. Differential regulation of NIS confers selective induction of functional NIS in thyroid cancer cells, as well as some breast cancer cells, leading to more efficient radioiodide therapy for thyroid cancer and a new strategy for breast cancer therapy. The potential for systemic radioiodide treatment of a range of other cancers, that do not express endogenous NIS, has been demonstrated in models with tumor-selective introduction of exogenous NIS.
Pharmacology & therapeutics.Pharmacol Ther.2012 Sep;135(3):355-70. Epub 2012 Jun 29.
Expression of the sodium iodide symporter (NIS) is required for efficient iodide uptake in thyroid and lactating breast. Since most differentiated thyroid cancer expresses NIS, β-emitting radioactive iodide is routinely utilized to target remnant thyroid cancer and metastasis after total thyroidect
PMID 22750642

Gibberellic acid induces α-amylase expression in adipose-derived stem cells.

Kasamatsu A, Iyoda M, Usukura K, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.SourceDepartment of Clinical Molecular Biology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. kasamatsua@faculty.chiba-u.jp
International journal of molecular medicine.Int J Mol Med.2012 Aug;30(2):243-7. doi: 10.3892/ijmm.2012.1007. Epub 2012 May 22.
Salivary α-amylase is the most important enzyme for oral digestion of dietary starch. Therefore, regeneration of the salivary glands via a tissue engineering approach is clearly required for patients with salivary gland dysfunction. Early during seed germination, the embryo synthesizes gibberellic
PMID 22641429

Japanese Journal

Immunohistochemical Localization of Relaxin and Its Receptors in Salivary Gland Tumors: A Preliminary Analysis

Utsunomiya Tadahiko,Yamaguchi Masaru,Ito Rie,Kasai Kazutaka,Yamamoto Hirotsugu
International Journal of Oral-Medical Sciences 12(2), 73-78, 2013
… Relaxin is a short circulating peptide hormone, and the major stored and circulatory form in humans is relaxin-2, generally known to have hormogenic functions and to act as an antifibrotic factor during childbirth in females. …
NAID 130003386568

Role of Stress-Related Brain-Derived Neurotrophic Factor (BDNF) in the Rat Submandibular Gland

Tsukinoki Keiichi,Saruta Juri
ACTA HISTOCHEMICA ET CYTOCHEMICA 45(5), 261-267, 2012
… However, the expression of neurotrophins other than NGF in the salivary gland has not been described in detail. … We found that BDNF expression increased within submandibular gland tissue in response to stress, suggesting that the salivary glands are sensitive to stress. … The salivary glands are likely to influence not only oral health, but also systemic organs. …
NAID 130001854257

Biophysiology of natriuretic peptides in the evolutionary varieties of vertebrate osmoregulatory systems from shark rectal to mammalian salivary glands

Mori Masahiko,Kasai Tadakatsu,Takai Yoshiaki,Shikimori Michio
Oral Medicine & Pathology 15(1), 3-13, 2010
… The present report points out the evolution of osmoregulatory systems and their effector organs, including the rectal glands of eels, frogs, and sharks; … the salt glands of birds; … and the salivary glands of mammals, including those of humans. …
NAID 130004509544