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「a protease inhibitor (trade name Norvir) used in treating HIV」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/09 02:40:49」(JST)

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  • Microarray Analysis Reveals Altered Lipid and Glucose Metabolism Genes in Differentiated, Ritonavir-Treated 3T3-L1 Adipocytes.
  • Loonam CR1, O'Dell SD, Sharp PA, Mullen A.
  • Current HIV research.Curr HIV Res.2016;14(1):37-46.
  • OBJECTIVE: HIV lipodystrophy is characterised by abnormal adipose tissue distribution and metabolism, as a result of altered adipocyte function and gene expression. The protease inhibitor ritonavir is associated with the development of lipodystrophy. Quantifying changes in adipogenic gene expression
  • PMID 26245760
  • Cell-Associated HIV-1 DNA and RNA Decay Dynamics During Early Combination Antiretroviral Therapy in HIV-1-Infected Infants.
  • Uprety P1, Chadwick EG2, Rainwater-Lovett K3, Ziemniak C3, Luzuriaga K4, Capparelli EV5, Yenokyan G6, Persaud D3.
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.Clin Infect Dis.2015 Dec 15;61(12):1862-70. doi: 10.1093/cid/civ688. Epub 2015 Aug 13.
  • BACKGROUND: The decay of human immunodeficiency virus type 1 (HIV-1)-infected cells during early combination antiretroviral therapy (cART) in infected infants is not defined.METHODS: HIV-1 DNA, including 2-long terminal repeat (2-LTR) circles, and multiply spliced (ms-) and unspliced (us-) HIV-1 RNA
  • PMID 26270687
  • Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset.
  • Chan JF1, Yao Y2, Yeung ML3, Deng W2, Bao L2, Jia L3, Li F2, Xiao C2, Gao H2, Yu P2, Cai JP3, Chu H3, Zhou J3, Chen H1, Qin C2, Yuen KY1.
  • The Journal of infectious diseases.J Infect Dis.2015 Dec 15;212(12):1904-13. doi: 10.1093/infdis/jiv392. Epub 2015 Jul 21.
  • Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe disease in human with an overall case-fatality rate of >35%. Effective antivirals are crucial for improving the clinical outcome of MERS. Although a number of repurposed drugs, convalescent-phase plasma, antiviral peptides, and
  • PMID 26198719


  • 症例報告 Ritonavir-boosted Atazanavirが被疑薬と考えられる遷延性血清クレアチニン上昇の1例
  • 森 尚義,谷口 晴記
  • 日本エイズ学会誌 = The journal of AIDS research 17(1), 25-29, 2015
  • NAID 40020383782
  • cART開始2年後に薬剤耐性化によるHIV脳症をきたした1例
  • 関谷 博顕,川本 未知,十河 正弥,吉村 元,今井 幸弘,幸原 伸夫
  • 臨床神経学 54(9), 721-725, 2014
  • 症例は57歳男性である.HIV(human immunodeficiency virus)に対するcART(combination antiretroviral therapy)中に認知機能低下が出現し,頭部MRIで両側大脳白質や脳幹部に病変をみとめた.髄液中HIV-RNAが血中HIV-RNAよりも高値を示し,薬剤耐性検査で抗HIV薬への耐性が判明.薬剤耐性と中枢神経移行性を考慮して抗HIV薬を変 …
  • NAID 130004696172
  • The Effect of the Different Treatment Protocols on Virological and Immunological Responses in Patients with HIV/AIDS
  • Sari Nagehan Didem,Fincanci Muzaffer,Soysal Ferda
  • Japanese Journal of Infectious Diseases 67(5), 339-344, 2014
  • … As the largest clusters, the lopinavir/ritonavir-based patient group (Group 1, n = 29) and efavirenz-based patient group (Group 2, n = 18) were compared. …
  • NAID 130004692231


Ritonavir is manufactured as Norvir by AbbVie, Inc.. The Food and Drug Administration (FDA) approved ritonavir on March 1, 1996, making it the seventh approved antiretroviral drug and the second approved protease inhibitor in the ...
Before taking ritonavir, tell your doctor and pharmacist if you are allergic to ritonavir, any other medications, or any of the ingredients in ritonavir tablets, capsules, or solution. Ask your pharmacist for a list of the ...


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ritonavir, RTV
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