WordNet
- a salt of phosphoric acid (同)orthophosphate, inorganic_phosphate
- carbonated drink with fruit syrup and a little phosphoric acid
- a pentose sugar important as a component of ribonucleic acid
PrepTutorEJDIC
- 〈U〉リン酸塩 / 《複数形で》リン酸肥料
- リボース(リボ核酸の加水分解によって得られる五炭糖)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/24 23:58:01」(JST)
[Wiki en表示]
Not to be confused with Riboflavin-5'-phosphate.
Ribose 5-phosphate
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| Names |
| IUPAC name
(2,3,4-Trihydroxy-5-oxo-pentoxy)phosphonic acid
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| Identifiers |
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CAS Registry Number
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4300-28-1 N |
| ChEBI |
CHEBI:58273 Y |
| ChemSpider |
70368 N |
InChI
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InChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h1,3-5,7-9H,2H2,(H2,10,11,12)/t3-,4+,5-/m0/s1 N
Key: PPQRONHOSHZGFQ-LMVFSUKVSA-N N
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InChI=1/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h1,3-5,7-9H,2H2,(H2,10,11,12)/t3-,4+,5-/m0/s1
Key: PPQRONHOSHZGFQ-LMVFSUKVBC
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| Jmol-3D images |
Image |
| MeSH |
ribose-5-phosphate |
| PubChem |
77982 |
SMILES
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C([C@H]([C@H]([C@H](C=O)O)O)O)OP(=O)(O)O
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| Properties |
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Chemical formula
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C5H11O8P |
| Molar mass |
230.110 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| N verify (what is: Y/N?) |
| Infobox references |
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Ribose 5-phosphate is both a product and an intermediate of the pentose phosphate pathway. The last step of the oxidative reactions in the pentose phosphate pathway is the production of ribulose 5-phosphate. Depending on the body's state, ribulose 5-phosphate can reversibly isomerize to ribose 5-phosphate. Ribulose 5-phosphate can alternatively undergo a series of isomerizations as well as transaldolations and transketolations that result in the production of other pentose phosphates as well as fructose 6-phosphate and glyceraldehyde 3-phosphate (both intermediates in glycolysis).
The enzyme ribose-phosphate diphosphokinase converts ribose-5-phosphate into phosphoribosyl pyrophosphate.
See also
References
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Pentose phosphate pathway metabolic intermediates
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|
| Oxidative |
- 6-Phosphogluconolactone
- 6-Phosphogluconate
- Ribulose 5-phosphate
- Ribose 5-phosphate
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| Nonoxidative |
- Xylulose 5-phosphate
- Sedoheptulose 7-phosphate
- Erythrose 4-phosphate
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Index of inborn errors of metabolism
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|
| Description |
- Metabolism
- Enzymes and pathways: citric acid cycle
- pentose phosphate
- glycoproteins
- glycosaminoglycans
- phospholipid
- cholesterol and steroid
- sphingolipids
- eicosanoids
- amino acid
- urea cycle
- nucleotide
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|
| Disorders |
- Citric acid cycle and electron transport chain
- Glycoprotein
- Proteoglycan
- Fatty-acid
- Phospholipid
- Cholesterol and steroid
- Eicosanoid
- Amino acid
- Purine-pyrimidine
- Heme metabolism
- Symptoms and signs
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|
| Treatment |
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Nucleotide metabolic intermediates
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| Purine metabolism |
| Anabolism |
| R5P→IMP: |
- R5P
- PRPP
- PRA
- GAR
- FGAR
- FGAM
- AIR
- CAIR
- SAICAR
- AICAR
- FAICAR
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| IMP→AMP: |
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| IMP→GMP: |
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| Catabolism |
- Hypoxanthine
- Xanthine
- Uric acid
- 5-Hydroxyisourate
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| Pyrimidine metabolism |
| Anabolism |
- Carbamoyl phosphate
- Carbamoyl aspartic acid
- 4,5-Dihydroorotic acid
- Orotic acid
- Orotidine 5'-monophosphate
- Uridine monophosphate
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|
| Catabolism |
| uracil: |
- Dihydrouracil
- 3-Ureidopropionic acid
- β-Alanine
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|
| thymine: |
- Dihydrothymine
- β-Ureidoisobutyric acid
- 3-Aminoisobutyric acid
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Index of inborn errors of metabolism
|
|
| Description |
- Metabolism
- Enzymes and pathways: citric acid cycle
- pentose phosphate
- glycoproteins
- glycosaminoglycans
- phospholipid
- cholesterol and steroid
- sphingolipids
- eicosanoids
- amino acid
- urea cycle
- nucleotide
|
|
| Disorders |
- Citric acid cycle and electron transport chain
- Glycoprotein
- Proteoglycan
- Fatty-acid
- Phospholipid
- Cholesterol and steroid
- Eicosanoid
- Amino acid
- Purine-pyrimidine
- Heme metabolism
- Symptoms and signs
|
|
| Treatment |
|
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Index of biochemical families
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| Carbohydrates |
- Alcohols
- Glycoproteins
- Glycosides
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| Lipids |
- Eicosanoids
- Fatty acids
- Glycerides
- Phospholipids
- Sphingolipids
- Steroids
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| Nucleic acids |
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| Proteins |
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| Other |
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UpToDate Contents
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English Journal
- Ribose-5-phosphate isomerase a regulates hepatocarcinogenesis via PP2A and ERK signaling.
- Ciou SC1, Chou YT, Liu YL, Nieh YC, Lu JW, Huang SF, Chou YT, Cheng LH, Lo JF, Chen MJ, Yang MC, Yuh CH, Wang HD.
- International journal of cancer. Journal international du cancer.Int J Cancer.2015 Jul 1;137(1):104-15. doi: 10.1002/ijc.29361. Epub 2014 Dec 12.
- The deregulated nonoxidative pentose phosphate pathway (PPP) is known to promote oncogenesis, but the molecular mechanism remains unknown. Here, we report that human ribose-5-phosphate isomerase A (RPIA) plays a role in human hepatocellular carcinoma (HCC). A significant increase in RPIA expression
- PMID 25429733
- Processing of protein ADP-ribosylation by Nudix hydrolases.
- Palazzo L1, Thomas B1, Jemth AS2, Colby T3, Leidecker O3, Feijs KL1, Zaja R1, Loseva O2, Puigvert JC2, Matic I3, Helleday T2, Ahel I1.
- The Biochemical journal.Biochem J.2015 Jun 1;468(2):293-301. doi: 10.1042/BJ20141554.
- ADP-ribosylation is a post-translational modification (PTM) of proteins found in organisms from all kingdoms of life which regulates many important biological functions including DNA repair, chromatin structure, unfolded protein response and apoptosis. Several cellular enzymes, such as macrodomain c
- PMID 25789582
Japanese Journal
- Modulation of Allosteric Regulation by E38K and G101N Mutations in the Potato Tuber ADP-glucose Pyrophosphorylase
- Bioscience, biotechnology, and biochemistry 77(9), 1854-1859, 2013-09-23
- NAID 10031202734
- Metabolic changes during cataract formation by ultraviolet radiation in the incubated rabbit lens
- 北海道醫學雜誌 = Acta medica Hokkaidonensia 84(6), 423-430, 2009-11-01
- NAID 10029924774
- D-Ribose Competitively Reverses Inhibition by D-Psicose of Larval Growth in Caenorhabditis elegans
Related Links
- Ribose 5-phosphate is both a product and an intermediate of the pentose phosphate pathway. The last step of the oxidative reactions in the pentose phosphate pathway is the production of ribulose-5-phosphate. Depending on the body's state ...
- リボース-5-リン酸（リボース-5-リンさん、英: Ribose 5-phosphate, R5P）は、 ペントースリン酸経路で作られる中間体の一つ。リボース-5-リン酸イソメラーゼによって リブロース-5-リン酸から作られ、 トランスケトラーゼによってセドヘプツロース-7-リン酸と グリセル ...
★リンクテーブル★
[★]
- 英
- ribose 5-phosphate, R5P
- 関
- ペントースリン酸回路
[★]
リボース5-リン酸 ribose 5-phosphate
[★]
- 関
- inorganic phosphate、orthophosphate、orthophosphoric acid、phospho、phosphoester、phosphoric、phosphoric acid、phosphoric acid ester、phosphorus
[★]
リボース
- 関
- D-ribose