rhodopsin

出典: meddic

ロドプシン

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/24 01:44:46」(JST)

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英文文献

  • Measuring membrane voltage with microbial rhodopsins.
  • Cohen AE, Hochbaum DR.SourceDepartment of Chemistry and Department of Chemical Biology and Physics, Harvard University, Cambridge, MA, USA.
  • Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2014;1071:97-108. doi: 10.1007/978-1-62703-622-1_8.
  • Membrane voltage (Vm) is a fundamental biological parameter that is essential for neuronal communication, cardiac activity, transmembrane transport, regulation of signaling, and bacterial motility. Optical measurements of Vm promise new insights into how voltage propagates within and between cells,
  • PMID 24052383
  • Unlocking the secrets of the gatekeeper: Methods for stabilizing and crystallizing GPCRs.
  • Bertheleme N, Chae PS, Singh S, Mossakowska D, Hann MM, Smith KJ, Hubbard JA, Dowell SJ, Byrne B.SourceDepartment of Life Sciences, Imperial College London, SW7 2AZ, UK.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2013 Nov;1828(11):2583-2591. doi: 10.1016/j.bbamem.2013.07.013. Epub 2013 Jul 18.
  • G-protein coupled receptors (GPCRs) are integral membrane cell surface receptors with key roles in mediating the cellular responses to a wide range of biologically relevant molecules including hormones, neurotransmitters and importantly the majority of currently available drugs. The first high-resol
  • PMID 23871992
  • Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding.
  • Vishnivetskiy SA, Ostermaier MK, Singhal A, Panneels V, Homan KT, Glukhova A, Sligar SG, Tesmer JJ, Schertler GF, Standfuss J, Gurevich VV.SourceDepartment of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
  • Cellular signalling.Cell Signal.2013 Nov;25(11):2155-62. doi: 10.1016/j.cellsig.2013.07.009. Epub 2013 Jul 17.
  • The effects of activating mutations associated with night blindness on the stoichiometry of rhodopsin interactions with G protein-coupled receptor kinase 1 (GRK1) and arrestin-1 have not been reported. Here we show that the monomeric form of WT rhodopsin and its constitutively active mutants M257Y,
  • PMID 23872075

和文文献

  • 結晶構造から見えてきたチャネルロドプシンの分子メカニズム
  • 蛋白質における光駆動プロトン移動と水素結合
  • ルミラーフィルムに吸着したバクテリアのもつ光駆動イオンポンプロドプシンタンパクの起電特性
  • 大学院研究年報 理工学研究科篇 (第43号/2013), 2013-07-01
  • NAID 120005394121

関連リンク

Rhodopsin Sensory rhodopsin II (rainbow colored) embedded in a lipid bilayer (heads red and tails blue) with Transducin (G t) below it. G t α is colored red, G t β blue, and G t γ yellow. There is a bound GDP molecule in the G t α ...
Contact rhodopsin for emailed copies or prints. Member of the Sports Journalists Association photographs taken by rhodopsin (unless otherwise stated) CRB Disclosure issued 2005, 2008 & 2010 (copies issued upon request)

関連画像

1xio » Sensory rhodopsin, monomer editors. Switch from dissolved rhodopsinDescription Rhodopsin.jpgrhodopsinRhodopsin ActivationMembrane Proteins: Rhodopsin


★リンクテーブル★
リンク元網膜」「ロドプシン
拡張検索rhodopsin kinase」「sensory rhodopsin

網膜」

  [★]

retina
眼球



  • 図:SP.275,

組織学

  • 10層よりなる (SP.275)
構造 細胞体
脈絡膜
網膜
1 色素上皮層   色素上皮細胞 pigment epithelium cell
2 杆体錐体層 rod and cone layer    
3 外境界膜      
4 外顆粒層 outer nuclear layer 視細胞 photoreceptor
5 外網状層 outer plexiform layer    
6 内顆粒層 inner nuclear layer 双極細胞 bipolar cell
水平細胞 horizontal cell
アマクリン細胞 amacrine cell
7 内網状層 inner plexiform layer    
8 神経節細胞層 ganglion cell layer 神経節細胞 ganglion cell
9 神経線維層 optic nerve fiber layer    
10 内境界膜      
  • 視細胞層(外顆粒層)には以下の細胞が存在


臨床関連


ロドプシン」

  [★]

rhodopsin
視紅 visual purple visuell purpura、桿体物質 rod pigment



rhodopsin kinase」

  [★]

ロドプシンキナーゼ

G-protein-coupled receptor kinase 1

sensory rhodopsin」

  [★]

感覚性ロドプシン




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