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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/07/11 20:39:46」(JST)

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1. C型肝炎ウイルス感染に対する試験的治療 investigational therapies for hepatitis c virus infection
2. 成人における肝移植：免疫抑制の概要 liver transplantation in adults overview of immunosuppression

The hepatitis E virus ORF1 'X-domain' residues form a putative macrodomain protein/Appr-1″-pase catalytic-site, critical for viral RNA replication.

Parvez MK1.
Gene.Gene.2015 Jul 15;566(1):47-53. doi: 10.1016/j.gene.2015.04.026. Epub 2015 Apr 11.
The hepatitis E virus (HEV) ORF1 gene encodes the non-structural polyprotein wherein the 'X-domain' still remains poorly defined. Cellular X-domain associated macrodomain protein/ADP-ribose-1″-monophosphatase (Appr-1″-pase) activities are also reported in coronaviruses (CoV), including identific
PMID 25870943

Replicon typing of plasmids carrying blaCTX-M-15 among Enterobacteriaceae isolated at the environment, livestock and human interface.

Zurfluh K1, Glier M1, Hächler H1, Stephan R2.
The Science of the total environment.Sci Total Environ.2015 Jul 15;521-522:75-8. doi: 10.1016/j.scitotenv.2015.03.079. Epub 2015 Mar 28.
One of the currently most important antibiotic resistance mechanisms in Enterobacteriaceae is based on the production of ESBL enzymes that inactivate β-lactam antibiotics including cephalosporins and monobactams by hydrolyzing their β-lactam ring. In humans, the most prevalent ESBL enzyme type is
PMID 25828415

Development of a nanoparticle-based oral vaccine for Atlantic salmon against ISAV using an alphavirus replicon as adjuvant.

Rivas-Aravena A1, Fuentes Y2, Cartagena J2, Brito T2, Poggio V3, La Torre J3, Mendoza H4, Gonzalez-Nilo F4, Sandino AM2, Spencer E2.
Fish & shellfish immunology.Fish Shellfish Immunol.2015 Jul;45(1):157-66. doi: 10.1016/j.fsi.2015.03.033. Epub 2015 Apr 7.
Adjuvants used in vaccine aquaculture are frequently harmful for the fish, causing melanosis, granulomas and kidney damage. Along with that, vaccines are mostly administered by injection, causing pain and stress to the fish. We used the DNA coding for the replicase of alphavirus as adjuvant (Ad) of
PMID 25862072