WordNet
- (medicine) the invasion of the body by pathogenic microorganisms and their multiplication which can lead to tissue damage and disease
- (phonetics) the alteration of a speech sound under the influence of a neighboring sound
- the pathological state resulting from the invasion of the body by pathogenic microorganisms
- (international law) illegality that taints or contaminates a ship or cargo rendering it liable to seizure
- moral corruption or contamination; "ambitious men are led astray by an infection that is almost unavoidable"
- an incident in which an infectious disease is transmitted (同)contagion, transmission
- any of a group of non-arboviruses including the rotavirus causing infant enteritis
PrepTutorEJDIC
- 〈U〉(病気の)伝染;感染 / 〈C〉伝染病
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- 1. コーガン症候群 cogans syndrome
- 2. 胆嚢嚢胞 biliary cysts
- 3. 胆道閉鎖症 biliary atresia
- 4. 肝内胆管の消失および胆管消失症候群 hepatic ductopenia and vanishing bile duct syndrome
- 5. 癌免疫療法の原則 principles of cancer immunotherapy
English Journal
- Expression of tapasin in rainbow trout tissues and cell lines and up regulation in a monocyte/macrophage cell line (RTS11) by a viral mimic and viral infection.
- Sever L1, Vo NT1, Bols NC1, Dixon B2.Author information 1Department of Biology, University of Waterloo, 200 University Ave W., Waterloo, Ontario N2L 3G1, Canada.2Department of Biology, University of Waterloo, 200 University Ave W., Waterloo, Ontario N2L 3G1, Canada. Electronic address: bdixon@uwaterloo.ca.AbstractTapasin is a transmembrane glycoprotein that acts as a bridge between the transporter associated with antigen processing and the MHC class I receptor in mammals. Through the development of antibody against trout tapasin, this report demonstrates the detection of trout tapasin as a N-glycosylated 48 kDa protein. Tissue and cell line distribution revealed that tapasin protein is expressed mainly in immune system organs and in rainbow trout epithelial cell lines from gill (RTgill-W1), liver (RTL-W1), and intestine (RTgutGC). An additional 20 kDa band was observed in tissues and cell lines, and appeared to be most prominent in RTgutGC but was absent in peripheral blood leukocytes. Tapasin 48 kDa protein was most strongly expressed in RTS11 (monocyte/macrophage cell line) and its regulation following dsRNA stimulation was explored. Upon poly I:C treatment and Chum Salmon Reovirus (CSV) infection, tapasin protein expression was upregulated up to 3.5 fold and 3 fold respectively, in parallel with increased expression of the glycosylated MH class I heavy chain, whereas the expression of the 20 kDa form remained unchanged. Overall this work demonstrates the induction of tapasin protein by dsRNA stimulation, which implies its possible conserved regulation during viral infection in teleost cells.
- Developmental and comparative immunology.Dev Comp Immunol.2014 May;44(1):86-93. doi: 10.1016/j.dci.2013.11.019. Epub 2013 Dec 7.
- Tapasin is a transmembrane glycoprotein that acts as a bridge between the transporter associated with antigen processing and the MHC class I receptor in mammals. Through the development of antibody against trout tapasin, this report demonstrates the detection of trout tapasin as a N-glycosylated 48
- PMID 24321527
- Sequencing and phylogenetic analysis of an avian reovirus genome.
- Teng L1, Xie Z, Xie L, Liu J, Pang Y, Deng X, Xie Z, Fan Q, Luo S, Feng J, Khan MI.Author information 1Guangxi Key Laboratory of Animal Vaccines and Diagnostics, Guangxi Veterinary Research Institute, 51 You Ai North Road, Nanning, 530001, Guangxi, China.AbstractAvian reovirus infection causes considerable economic loss to the commercial poultry industry. Live-attenuated vaccine strain S1133 (v-S1133, derived from parent strain S1133) is considered the safest and most effective vaccine and is currently used worldwide. To identify the genes responsible for its attenuation, DNA sequences of open reading frames (ORF) of S1133 and its parent strains S1133, 1733, 526, and C78 along with three field isolates (GuangxiR1, GuangxiR2, and GX110058) and one isolate (GX110116) from a vaccinated chicken were performed. The sequence data were compared with available sequences in nucleotide sequence databases of American (AVS-B, 138, 176) and Chinese (C-98 and T-98) origin. Sequence analysis identified that several v-S1133 specific nucleotide substitutions existed in the ORFs of λA, λB, λC, μA, μB, μNS, σA, σB, and σNS genes. The v-S1133 strain could be differentiated from the field-isolated strains based on single nucleotide polymorphisms. Phylogenetic analysis revealed that v-S1133 shared the highest sequence homologies with S1133 and reovirus isolates from China, grouped together in one cluster. Chinese isolates were clearly more distinct from the American reovirus AVS-B strain, which is associated with runting-stunting syndrome in broilers.
- Virus genes.Virus Genes.2014 Apr;48(2):381-6. doi: 10.1007/s11262-013-1029-5. Epub 2013 Dec 25.
- Avian reovirus infection causes considerable economic loss to the commercial poultry industry. Live-attenuated vaccine strain S1133 (v-S1133, derived from parent strain S1133) is considered the safest and most effective vaccine and is currently used worldwide. To identify the genes responsible for i
- PMID 24368760
- The mammalian orthoreovirus bicistronic M3 mRNA initiates translation using a 5' end-dependent, scanning mechanism that does not require interaction of 5'-3' untranslated regions.
- Sagar V1, Murray KE2.Author information 1Department of Biological Sciences, Florida International University, Miami, FL 33199, United States. Electronic address: vsaga001@fiu.edu.2Department of Biological Sciences, Florida International University, Miami, FL 33199, United States.AbstractMammalian orthoreovirus mRNAs possess short 5' UTR, lack 3' poly(A) tails, and may lack 5' cap structures at late times post-infection. As such, the mechanisms by which these viral mRNAs recruit ribosomes remain completely unknown. Toward addressing this question, we used bicistronic MRV M3 mRNA to analyze the role of 5' and 3' UTRs during MRV protein synthesis. The 5' UTR was found to be dispensable for translation initiation; however, reducing its length promoted increased downstream initiation. Modifying start site Kozak context altered the ratio of upstream to downstream initiation, whereas mutations in the 3' UTR did not. Moreover, an M3 mRNA lacking a 3' UTR was able to rescue MRV infection to WT levels in an siRNA trans-complementation assay. Together, these data allow us to propose a model in which the MRV M3 mRNA initiates translation using a 5' end-dependent, scanning mechanism that does not require the viral mRNA 3' UTR or 5'-3' UTRs interaction.
- Virus research.Virus Res.2014 Apr;183:30-40. doi: 10.1016/j.virusres.2014.01.018. Epub 2014 Jan 30.
- Mammalian orthoreovirus mRNAs possess short 5' UTR, lack 3' poly(A) tails, and may lack 5' cap structures at late times post-infection. As such, the mechanisms by which these viral mRNAs recruit ribosomes remain completely unknown. Toward addressing this question, we used bicistronic MRV M3 mRNA to
- PMID 24486484
Japanese Journal
- Seroepidemiology of Reovirus in Healthy Dogs in Six Prefectures in Japan
- HWANG Chung Chew,MOCHIZUKI Masami,MAEDA Ken,OKUDA Masaru,MIZUNO Takuya
- Journal of Veterinary Medical Science 76(3), 471-475, 2014
- … Reovirus infection is common in mammals. … However, seroepidemiological data of reovirus neutralizing antibodies are limited in dogs. … In this study, sera of 65 healthy dogs from six prefectures across Japan were tested for neutralizing antibodies against reovirus serotype 1 strain Lang (T1L), serotype 2 strain Amy (T2A) and serotype 3 strain Dearing (T3D) using plaque reduction neutralization test (PRNT). …
- NAID 130003382393
- サマーフラウンダー稚魚にみられたレオウイルス様ウイルス感染症
- 和田 新平,倉田 修,畑井 喜司雄,NOGA Edward J.,DYKSTRA Michael J.,BURKE John S.
- 魚病研究 44(3), 151-153, 2009-09-15
- 米国で人工種苗生産されたサマーフラウンダーParalichthys dentatusの稚魚に亜急性から慢性の大量死亡が発生した。病魚には、壊死した多核巨細胞（合胞体）が多発する重篤な壊死性肝炎が認められた。透過型電顕下では、これら合胞体の細胞質内に結晶様配列をしたレオウイルス様の粒子がみられたことから、本病はウイルス病であることが示唆された。本報告はサマーフラウンダーでウイルス病が疑われた初の事例 …
- NAID 10026105780
- サマーフラウンダー稚魚にみられたレオウイルス様ウイルス感染症
- 和田 新平,倉田 修,畑井 喜司雄 [他],Noga Edward J.,Dykstra Michael J.,Burke John S.
- 魚病研究 44(3), 151-153, 2009
- … The cytoplasms of syncytia contained paracrystalline arrays of reovirus-like particles, strongly suggesting that the epidemic was caused by the virus. … This is the first report of a putative viral infection in summer flounder. …
- NAID 130000133069
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★リンクテーブル★
| リンク元 | 「レオウイルス感染症」「Reoviridae infection」「レオウイルス感染」 |
| 関連記事 | 「infection」 |
「レオウイルス感染症」
「Reoviridae infection」
「レオウイルス感染」
「infection」
- n.