近位尿細管性アシドーシス
WordNet
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- constituting a tube; having hollow tubes (as for the passage of fluids) (同)cannular, tubelike, tube-shaped, vasiform
- the 9th letter of the Roman alphabet (同)i
- abnormally high acidity (excess hydrogen-ion concentration) of the blood and other body tissues
PrepTutorEJDIC
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
- 管状の,管から成る
- 『私は』私が
- iodineの化学記号
- 酸性症,酸中毒(血液中のアルカリ濃度が異常に低い状態)
UpToDate Contents
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English Journal
- Ifosfamide-induced Fanconi syndrome with diabetes insipidus.
- Leem AY, Kim HS, Yoo BW, Kang BD, Kim MH, Rha SY, Kim HS.
- The Korean journal of internal medicine.Korean J Intern Med.2014 Mar;29(2):246-9. doi: 10.3904/kjim.2014.29.2.246. Epub 2014 Feb 27.
- Ifosfamide-induced Fanconi syndrome is a rare complication that typically occurs in young patients due to a cumulative dose of ifosfamide > 40-60 g/m(2), a reduction in kidney mass, or concurrent cisplatin treatment. It is usually characterized by severe and fatal progression accompanied by type
- PMID 24648810
- Vacuolar ATPases and their role in vision.
- Shine L1, Kilty C, Gross J, Kennedy B.
- Advances in experimental medicine and biology.Adv Exp Med Biol.2014;801:97-103. doi: 10.1007/978-1-4614-3209-8_13.
- Vacuolar ATPases (v-ATPases) hydrolyze adenosine triphospate (ATP) to pump protons across cell membranes. Mutations in v-ATPase subunits are implicated in three human disorders: distal renal tubular acidosis, osteopetrosis, and cutis laxa type II. In the eye, the role of v-ATPases is only emerging.
- PMID 24664686
- [Tubular renal acidosis].
- Seidowsky A1, Moulonguet-Doleris L2, Hanslik T3, Yattara H2, Ayari H2, Rouveix E3, Massy ZA4, Prinseau J4.
- La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne.Rev Med Interne.2014 Jan;35(1):45-55. doi: 10.1016/j.revmed.2013.08.012. Epub 2013 Sep 24.
- Renal tubular acidosis (RTAs) are a group of metabolic disorders characterized by metabolic acidosis with normal plasma anion gap. There are three main forms of RTA: a proximal RTA called type II and a distal RTA (type I and IV). The RTA type II is a consequence of the inability of the proximal tubu
- PMID 24070792
Japanese Journal
- 土井 研人,寺本 信嗣,細井 孝之,宮尾 益理子,松瀬 健,鳥羽 研二,大内 尉義
- 日本老年医学会雑誌 35(6), 477-481, 1998-06-25
- NAID 10008482258
- 複数の要因によって発現したと考えられるⅣ型尿細管性アシドーシスを呈した糖尿病性腎症の1剖検例
- 大江 厚,金内 雅夫,勝山 慶之,鵜山 秀人,嶋 宏子,藤本 隆,椎木 英夫,土肥 和紘,松岡 弘樹,市島 國雄
- 奈良医学雑誌 49(2), 118-122, 1998-04-30
- … We report a case of diabetic nephropathy and type Ⅳ renal tubular acidosis in a 65-year-old woman. … She was admitted to our hospital because of unstable angina pectoris and was found to have severe metabolic acidosis and hyperkalemia. … Renal biopsy revealed diabetic nephropathy (diffuse Ⅲ) and interstitial fibrosis. …
- NAID 120004973355
- Renal Tubular Acidosis type II Secondary to .LAMBDA.-Light Chain Excretion in an Elderly Patient with Multiple Myeloma.
- 土井 研人,寺本 信嗣,細井 孝之,宮尾 益理子,松瀬 健,鳥羽 研二,大内 尉義
- 日本老年医学会雑誌 35(6), 477-481, 1998
- … A 73-year-old women was admitted to the geriatric ward of the University of Tokyo Hospital with anemia, osteepeina, and renal dysfunction. … Although symptoms typical of multiple myeloma such as punched-out lesions and hyperproteinemia were not found, protein electrophoresis revealed that λtype Bence-Jones protein was excreted in urine. …
- NAID 130003652434
Related Links
- Proximal renal tubular acidosis is a disease that occurs when the kidneys don't properly remove acids from the blood into the urine. As a result, too much ... When the body performs its normal functions, it produces ...
- Renal tubular acidosis, type 2 symptoms, causes, diagnosis, and treatment information for Renal tubular acidosis, type 2 (Proximal Renal Tubular Acidosis) with alternative diagnoses, full-text book chapters, misdiagnosis, research ...
★リンクテーブル★
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- 英
- proximal renal tubular acidosis, proximal RTA, pRTA, proximal tubular acidosis
- 同
- 2型尿細管性アシドーシス、II型尿細管性アシドーシス、尿細管性アシドーシス2型、尿細管性アシドーシスII型
- 2型腎尿細管性アシドーシス、II型腎尿細管性アシドーシス、腎尿細管性アシドーシス2型、腎尿細管性アシドーシスII型
- type 2 renal tubular acidosis, type II renal tubular acidosis, renal tubular acidosis type 2, renal tubular acidosis type II
- type 2 RTA, type II RTA, RTA type 2, RTA type II
- 関
- 尿細管性アシドーシス、アシドーシス。遠位尿細管性アシドーシス
[show details]
概念
- 腎尿細管アシドーシスの中で、近位尿細管における重炭酸イオン再吸収障害に伴う酸排泄障害を原因とするものをいう。
- アニオンギャップが正常な高Cl性の代謝性アシドーシス
病因
- 参考1
-
- 多発性骨髄腫 → 成人におけるRTA type 2の原因で最多
- 薬物性
病態
- 参考1
- 重炭酸が何らかの原因により再吸収されない。 → 高Cl性代謝性アシドーシス
- リン酸、グルコース、尿酸、アミノ酸が再吸収されない。 → 低リン酸血症、腎性糖尿、低尿酸症、アミノ酸尿
- 水・電解質と酸塩基平衡 改訂第2版 p.151
- 近位尿細管で重炭酸イオン(その他各種電解質も)の再吸収が低下するために血清HCO3-が低下する
- 血清HCO3-が15mEq/l以下になると再吸収が可能となるので、proximal RTAにおいて血清HCO3-が15-17mEq/l以下になることはまれ。
- YN
- 近位尿細管におけるNa+/H+交輸送体の異常や、炭酸脱水酵素遺伝子異常、Na+/HCO3-共輸送体遺伝子異常
治療
- アシドーシス補正：重曹
- 低カリウム血症：カリウム補充
参考
- わかりにくい
- http://omim.org/entry/179830
- 2. [charged] Etiology and diagnosis of distal (type 1) and proximal (type 2) renal tubular acidosis - uptodate [1]
- 3. [charged] Pathophysiology of renal tubular acidosis and the effect on potassium balance - uptodate [2]
[★]
- (windows)ファイル内容表示(linux -> cat])
- ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html
- 関
- form、mode、pattern、type specimen、typed
[★]
- 関
- canalicular、kidney tubule、renal tubular、renal tubule、tracheary、tubule、uriniferous tubule
[★]
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- 関
- kidney tubule、renal tubule、tubular、tubule、uriniferous tubule