WordNet

(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
the syllable naming the second (supertonic) note of any major scale in solmization (同)ray
informal term for information; "give me the gen on your new line of computers"

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1. びまん性大細胞型B細胞性リンパ腫および原発性縦隔大細胞型B細胞リンパ腫の病理学 pathobiology of diffuse large b cell lymphoma and primary mediastinal large b cell lymphoma
2. リードスタンバーグ細胞およびホジキンリンパ腫の病因 the reed sternberg cell and the pathogenesis of hodgkin lymphoma
3. 原発性縦隔大細胞型B細胞リンパ腫 primary mediastinal large b cell lymphoma
4. 乾癬性関節炎の病因 pathogenesis of psoriatic arthritis
5. 原発性皮膚濾胞中心リンパ腫 primary cutaneous follicle center lymphoma

Involvement of Relish gene from Macrobrachium rosenbergii in the expression of anti-microbial peptides.

Shi YR1, Jin M2, Ma FT1, Huang Y1, Huang X1, Feng JL1, Zhao LL1, Chen YH3, Ren Q4.
Developmental and comparative immunology.Dev Comp Immunol.2015 Oct;52(2):236-44. doi: 10.1016/j.dci.2015.05.008. Epub 2015 May 27.
Relish is an NF-kB transcription factor involved in immune-deficiency (IMD) signal pathway. In this study, a Relish gene (MrRelish) was identified from Macrobrachium rosenbergii. The full length of MrRelish comprises 5072 bp, including a 3510 bp open reading frame encoding a 1169 bp amino acid prote
PMID 26026243

Evolution of akirin family in gene and genome levels and coexpressed patterns among family members and rel gene in croaker.

Liu T1, Gao Y2, Xu T3.
Developmental and comparative immunology.Dev Comp Immunol.2015 Sep;52(1):17-25. doi: 10.1016/j.dci.2015.04.010. Epub 2015 Apr 23.
Akirins, which are highly conserved nuclear proteins, are present throughout the metazoan and regulate innate immunity, embryogenesis, myogenesis, and carcinogenesis. This study reports all akirin genes from miiuy croaker and analyzes comprehensively the akirin gene family combined with akirin genes
PMID 25912355

The early stages of the immune response of the European abalone Haliotis tuberculata to a Vibrio harveyi infection.

Cardinaud M1, Dheilly NM2, Huchette S3, Moraga D4, Paillard C5.
Developmental and comparative immunology.Dev Comp Immunol.2015 Aug;51(2):287-97. doi: 10.1016/j.dci.2015.02.019. Epub 2015 Mar 9.
Vibrio harveyi is a marine bacterial pathogen responsible for episodic abalone mortalities in France, Japan and Australia. In the European abalone, V. harveyi invades the circulatory system in a few hours after exposure and is lethal after 2 days of infection. In this study, we investigated the res
PMID 25766281

Targeted Suppression of EVI1 Oncogene Expression by Sequence-Specific Pyrrole-Imidazole Polyamide.

Syed Junetha,Pandian Ganesh N,Sato Shinsuke,Taniguchi Junichi,Chandran Anandhakumar,Hashiya Kaori,Bando Toshikazu,Sugiyama Hiroshi
Chemistry & biology 21(10), 1370-1380, 2014-10-23
… Its selective modulation is thought to alter the cancer-specific gene regulatory networks. … Herein, we report a sequence-specific pyrrole-imidazole polyamide, PIP1, which can target specific base pairs of the REL/ELK1 binding site in the EVI1 minimal promoter. … Whole-transcriptome analysis confirmed that PIP1 affected a fraction of EVI1-mediated gene regulation. …
NAID 120005512270

Interferon regulatory factor-4 activates IL-2 and IL-4 promoters in cooperation with c-Rel.

Shindo Hisakazu,Yasui Kiyoshi,Yamamoto Kazuo,Honma Kiri,Yui Katsuyuki,Kohno Tomoko,Ma Yuhua,Chua Koon Jiew,Kubo Yoshinao,Aihara Hitoshi,Ito Takashi,Nagayasu Takeshi,Matsuyama Toshifumi,Hayashi Hideki
Cytokine 56(3), 564-572, 2011-12
… Fourteen proteins were identified in the IRF-4-binding complex, including endogenous IRF-4 and the nuclear factor-kappaB (NF-κB) family member, c-Rel. … The specific association of IRF-4 with c-Rel was confirmed by immunoprecipitation experiments, and IRF-4 was shown to enhance the c-Rel-dependent binding and activation of the interleukin-4 (IL-4) promoter region. …
NAID 120003659758