quinacrine

出典: meddic

キナクリン


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「a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria」
quinacrine hydrochloride, mepacrine, Atabrine

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/19 02:05:10」(JST)

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英文文献

  • EFFECTS OF GENETIC KNOCK-DOWN OF ORGANIC ANION TRANSPORTER GENES ON SECRETION OF FLUORESCENT ORGANIC IONS BY MALPIGHIAN TUBULES OF Drosophila melanogaster.
  • Chahine S, Seabrooke S, O'Donnell MJ.SourceDepartment of Biology, McMaster University, Hamilton, Ontario, Canada.
  • Archives of insect biochemistry and physiology.Arch Insect Biochem Physiol.2012 Dec;81(4):228-40. doi: 10.1002/arch.21066. Epub 2012 Sep 12.
  • An earlier study has shown that RNAi knock-down of a single organic anion transporter (OAT) gene in the principal cells of Drosophila Malpighian tubules is associated with reductions in the expression of multiple, functionally related genes. In this study, we measured the rates of secretion of four
  • PMID 22972675
  • Integrin participates in the effect of thyroxine on plasma membrane in immature rat testis.
  • Zanatta AP, Zanatta L, Gonçalves R, Zamoner A, Silva FR.SourceDepartamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis-Santa Catarina, Brazil.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2012 Nov 5. pii: S0304-4165(12)00308-X. doi: 10.1016/j.bbagen.2012.10.022. [Epub ahead of print]
  • BACKGROUND: The secretory activity of Sertoli cells (SC) is dependent on ion channel functions and protein synthesis and is critical to ongoing spermatogenesis. The aim of this study was to investigate the mechanism of action associated with a non-metabolizable amino acid [(14)C]-MeAIB (α-(methyl-a
  • PMID 23137442

和文文献

  • プリオン病の治療動向 (増大特集 神経疾患と感染症update)
  • 坪井 義夫
  • Brain and nerve : 神経研究の進歩 67(7), 941-946, 2015-07
  • NAID 40020533006
  • 5-Azadeoxycytidine induced heteromorphic undercondensation in the C-blocks of X chromosomes of three mammalian species, Pipistrellus abramus, Millardia meltada, and Apodemus argenteus
  • Okada Michitada,Obara Yoshitaka,Tsuchiya Kimiyuki
  • Chromosome Science 17(1-4), 3-7, 2014
  • … argenteus, as revealed by fluorescent staining with quinacrine mustard (QM) and chromomycin A3 (CMA). …
  • NAID 130004862081
  • プリオン病の治療:現状と研究の最前線
  • 坪井 義夫
  • 臨床神経学 53(11), 1255-1257, 2013
  • プリオン病は,脳内に異常プリオン蛋白の凝集がみられ,臨床的にはいったん発症すると例外なく進行性,致死性の経過をたどる難病である.プリオン病に対する有効な治療薬はなく,その開発が期待される.これまでマウスをもちいたプリオン蛋白感染実験で,その発症遅延効果が示されたキナクリン,ペントサンポリサルフェート(PPS)の脳室内持続投与など少数の薬剤が実際に臨床応用されたが,明らかな臨床改善効果は証明されなか …
  • NAID 130004505405

関連リンク

[Quinacrine Dihydrochloride] [69-05-6] | 価格や在庫、物性値などの詳細情報ページです。 ... 別名 (英名) 6-Chloro-9-(4-diethylamino-1-methylbutyl)amino-2-methoxyacridine Dihydrochloride Hydrate 和名 キナクリン二塩酸塩水和物 和名 ...
Uses Its main effects are as an antiprotozoal, antirheumatic and an intrapleural sclerosing agent. [1] Antiprotozoal use include targeting Giardiasis, where quinacrine is indicated as a primary agent for patients with metronidazole-resistant giardiasis and patients who should not receive or can not tolerate metronidazole.

関連画像

Quinacrine dihydrochloridequinacrine - a drug (trade name Atabrine Molecular structure of quinacrine .QuinacrineFile:Quinacrine mustard in Trypanothione Transmission of an unbalanced (Y;1


★リンクテーブル★
リンク元駆虫薬」「キナクリン
拡張検索quinacrine mustard

駆虫薬」

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anthelmintic, anthelmintics
anthelmintica

http://en.wikipedia.org/wiki/Anthelmintic

antiplatyhelmintic agents Antitrematodals
(schistosomicides)
binds tubulin benzimidazole (Triclabendazole#)
acetylcholinesterase inhibitor phosphonic acid (metrifonate)
Other/unknown quinoline (praziquantel#, oxamniquine#) · phenol (bithionol) · thiazole ([[niridazole]) · arylsulfonate (stibophen)
anticestodals
(taeniacides)
binds tubulin benzimidazole (albendazole#)
Other/unknown salicylanilide (niclosamide)# · aminoacridine (quinacrine) · butyrophenone (desaspidin) · chlorophenol (dichlorophen)
antinematodal agents
(macrofilaricides)
binds tubulin benzimidazole (mebendazole#, thiabendazole, albendazole#, fenbendazole, ciclobendazole, flubendazole)
chloride channel macrolide (ivermectin#)
NMDA tetrahydropyrimidine (pyrantel#, pyrantel pamoate, oxantel)
Other/unknown piperazine (piperazine · diethylcarbamazine#) · thiazole (levamisole#) · quinolinium (pyrvinium) · benzylammonium (bephenium) · naphthalenesulfonate (suramin#)  · tribendimidine


キナクリン」

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quinacrine
メパクリン


quinacrine mustard」

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キナクリンマスタード




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