WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- in favor of a proposition, opinion, etc.
- an argument in favor of a proposal
- in favor of (an action or proposal etc.); "a pro vote"
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- indicating the first or earliest or original; "`proto is a combining form in a word like `protolanguage that refers to the hypothetical ancestor of another language or group of languages"
- a gene that disposes normal cells to change into cancerous tumor cells (同)transforming_gene
PrepTutorEJDIC
- carbonの化学記号
- =professional
- 賛成論;賛成票(者) / 賛成して
- 蛋白(たんばく)質
UpToDate Contents
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- 1. 前立腺癌の分子生物学 molecular biology of prostate cancer
- 2. 悪性腫瘍に関連した凝固亢進状態の病因 pathogenesis of the hypercoagulable state associated with malignancy
- 3. 機械的人工換気の肺障害の炎症メカニズム inflammatory mechanisms of lung injury during mechanical ventilation
- 4. プロテインC欠乏症：臨床症状および診断 protein c deficiency clinical manifestations and diagnosis
- 5. 第V因子ライデンおよび活性化プロテインC抵抗性：臨床症状および診断 factor v leiden and activated protein c resistance clinical manifestations and diagnosis
English Journal
- DNA-binding regulates site-specific ubiquitination of IRF-1.
- Landré V, Pion E, Narayan V, Xirodimas DP, Ball KL.SourceCell Signalling Unit, Edinburgh Cancer Research Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Rd South, Edinburgh EH4 2XR, UK.
- The Biochemical journal.Biochem J.2013 Feb 1;449(3):707-17. doi: 10.1042/BJ20121076.
- Understanding the determinants for site-specific ubiquitination by E3 ligase components of the ubiquitin machinery is proving to be a challenge. In the present study we investigate the role of an E3 ligase docking site (Mf2 domain) in an intrinsically disordered domain of IRF-1 [IFN (interferon) reg
- PMID 23134341
- A novel Aurora-A-mediated phosphorylation of p53 inhibits its interaction with MDM2.
- Hsueh KW, Fu SL, Chang CB, Chang YL, Lin CH.SourceDepartment of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan.
- Biochimica et biophysica acta.Biochim Biophys Acta.2013 Feb;1834(2):508-15. doi: 10.1016/j.bbapap.2012.11.005. Epub 2012 Nov 28.
- PURPOSE: Crosstalk between Aurora-A kinase and p53 has been proposed. While the genetic amplification of Aurora-A has been observed in many human cancers, how p53 is regulated by Aurora-A remains ambiguous. In this study, Aurora-A-mediated phosphorylation of p53 was analyzed by mass spectrometry in
- PMID 23201157
- MDM2, MDMX and p53 in oncogenesis and cancer therapy.
- Wade M, Li YC, Wahl GM.SourceCenter for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia, Via Adamello 16, 20139 Milan, Italy.
- Nature reviews. Cancer.Nat Rev Cancer.2013 Feb;13(2):83-96. doi: 10.1038/nrc3430. Epub 2013 Jan 10.
- The MDM2 and MDMX (also known as HDMX and MDM4) proteins are deregulated in many human cancers and exert their oncogenic activity predominantly by inhibiting the p53 tumour suppressor. However, the MDM proteins modulate and respond to many other signalling networks in which they are embedded. Recent
- PMID 23303139
Related Links
- "Proto-Oncogene Proteins c-mdm2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). ... An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR ...
- ABSTRACT The mouse double minute 2 (mdm2) proto-oncogene was originally discovered as one of three genes that was amplified in a tumorigenic cell line derived from non-transformed Balb/c cells. Consistent with the expression ...
Related Pictures
★リンクテーブル★
| リンク元 | 「c-Mdm2」「癌原遺伝子産物c-Mdm2」 |
| 関連記事 | 「C」「oncogene protein」「pro」「proto」「Md」 |
「c-Mdm2」
「癌原遺伝子産物c-Mdm2」
「C」
- 炭素 carbon
- シトシン cytosine
- システイン cysteine
- シチジン
- セルシウス度 摂氏 degrees Celsius degree C
- 産婦人科領域で「子宮外頚 子宮外頚部 exocervix」を表現するための略語
「oncogene protein」
「pro」
- comb form.
- (前;前駆の;促進性の)プロ
「proto」
- comb form.