WordNet

a protein in blood plasma that is the inactive precursor of thrombin (同)factor_II

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1. 稀な遺伝性凝固異常 rare inherited coagulation disorders
2. ビタミンKの概要 overview of vitamin k
3. 出血性素因を有する成人患者へのアプローチ approach to the adult patient with a bleeding diathesis
4. β-ラクタム系抗生物質：作用機序、耐性および有害作用 beta lactam antibiotics mechanisms of action and resistance and adverse effects
5. 血友病の臨床症状および診断 clinical manifestations and diagnosis of hemophilia

Dahlberg S1, Nilsson CU1,2, Kander T1,2, Schött U1,2.
Scandinavian journal of clinical and laboratory investigation.Scand J Clin Lab Invest.2017 Jul;77(4):267-274. doi: 10.1080/00365513.2017.1303190. Epub 2017 Mar 20.
PMID 28319421

Clinical outcomes and a high prevalence of abnormalities on comprehensive arterial and venous thrombophilia screening in TIA or ischaemic stroke patients with a patent foramen ovale, an inter-atrial septal aneurysm or both.

Lim ST1, Murphy SJX1, Smith DR2, Williams J3, Navarro SG3, McCabe J3, Moore DP4, McHugh J5, McCabe DJH6.
Journal of the neurological sciences.J Neurol Sci.2017 Jun 15;377:227-233. doi: 10.1016/j.jns.2017.04.014. Epub 2017 Apr 12.
PMID 28477701

Evidence of both von Willebrand factor deposition and factor V deposition onto AL amyloid as the cause of a severe bleeding diathesis.

Harrison JS1, Frazier SR, McConnell DD, Yasar SJ, Melnyk N, Salaru G.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.Blood Coagul Fibrinolysis.2017 Jun;28(4):342-347. doi: 10.1097/MBC.0000000000000600.
PMID 27676646

山田和俊,北村和哉,丹尾幸樹,島上哲朗,荒井邦明,柿木嘉平太,山下太郎,酒井佳夫,水腰英四郎,金子周一
日本消化器内視鏡学会雑誌 56(3), 451-456, 2014
症例は57歳男性，食道静脈瘤に対し内視鏡的硬化療法（EIS）を施行したが，その際の止血に難渋した．凝固能の低下，プロトロンビン時間（PT），ヘパプラスチンテスト（HpT）の解離，第V因子の著明な低下，第V因子インヒビターの上昇などを認め，後天性第V因子欠損症と診断した．診断時には出血症状を認めておらず，慎重に経過観察をしたところ，自然経過にて凝固能は改善と第V因子インヒビター力価の低下を認めた．内 …
NAID 130003395970

神保充孝,郷良秀典
日本呼吸器外科学会雑誌 28(2), 183-187, 2014
症例は18歳，男性．17歳時に左自然気胸に対し手術が行われた．その際，軽度のPT延長を認め，精査の結果，先天性第VII因子欠乏症と診断された．今回，胸痛のため当科を受診し，左自然気胸術後再発の診断で胸腔鏡下に手術を施行した．肺尖部に認めたブラを処理し，止血を確認後，14Fr胸腔ドレーンを留置し手術を終了した．術翌日の胸部レントゲン写真で大量の胸水を認め，22Fr胸腔ドレーンに入れ換えたところ，大量 …
NAID 130003394013

Management of postoperative hemorrhage associated with factor VIII inhibitor: report of a case

Onishi Ichiro,Kayahara Masato,Munemoto Masayoshi,Sakai Seisyo,Makino Isamu,Hayashi Hironori,Nakagawara Hisatoshi,Tajima Hidehiro,Takamura Hiroyuki,Kitagawa Hirohisa,Tani Takashi,Ohta Tetsuo
Surgery Today 43(9), 1058-1061, 2013-09
… An extensive coagulation work-up revealed factor VIII deficiency (1 %), and a diagnosis of an acquired factor VIII deficiency was established when a factor VIII inhibitor of 8 Bethesda units was demonstrated. … The patient was treated with activated prothrombin complex concentrate (aPCCs) and bloody discharge was stopped within 3 days. …
NAID 120004754695