proteolytic fragment

• タンパク質分解フラグメント

WordNet

1. a piece broken off or cut off of something else; "a fragment of rock"
2. an incomplete piece; "fragments of a play"
3. of or relating to proteolysis

PrepTutorEJDIC

1. (…の)『破片』,断片《+『of』+『名』》 / (特に詩文などの)未完の部分,断章《+『of』+『名』》 / ばらばらになる,砕ける / …‘を'ばらばらに壊す

UpToDate Contents

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• 1. 補体系の概要および臨床的評価 overview and clinical assessment of the complement system
• 2. 補体経路 complement pathways
• 3. 皮質下梗塞および白質脳症を伴う常染色体優性脳動脈症（CADASIL） cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy cadasil
• 4. 免疫グロブリンの構造 structure of immunoglobulins
• 5. 自己免疫性溶血性貧血の病因：寒冷凝集素症 pathogenesis of autoimmune hemolytic anemia cold agglutinin disease

English Journal

• Traumatic brain injury causes frontotemporal dementia and TDP-43 proteolysis.

• Wang HK1, Lee YC2, Huang CY3, Liliang PC4, Lu K5, Chen HJ5, Li YC6, Tsai KJ7.
• Neuroscience.Neuroscience.2015 Aug 6;300:94-103. doi: 10.1016/j.neuroscience.2015.05.013. Epub 2015 May 14.
• Traumatic brain injury (TBI) is a major risk factor for dementia. Recently, TBI has also been suggested as a risk factor for frontotemporal dementia (FTD), and plasma immunoreactivity to the TAR-DNA binding protein 43 (TDP-43) has been observed in both patients with acute TBI and long-term survivors
• PMID 25982564

• Cyclin-Dependent kinase 5 targeting prevents β-Amyloid aggregation involving glycogen synthase kinase 3β and phosphatases.

• Castro-Alvarez JF1, Uribe-Arias A1, Cardona-Gómez GP1.
• Journal of neuroscience research.J Neurosci Res.2015 Aug;93(8):1258-66. doi: 10.1002/jnr.23576. Epub 2015 Feb 24.
• Inappropriate activation of cyclin-dependent kinase 5 (CDK5) resulting from proteolytic release of the activator fragment p25 from the membrane contributes to the formation of neurofibrillary tangles, β-amyloid (βA) aggregation, and chronic neurodegeneration. At 18 months of age, 3× Tg-AD mice we
• PMID 25711385

• A Cell-Based Assay Reveals Nuclear Translocation of Intracellular Domains Released by SPPL Proteases.

• Mentrup T1, Häsler R2, Fluhrer R3,4, Saftig P1, Schröder B1.
• Traffic (Copenhagen, Denmark).Traffic.2015 Aug;16(8):871-92. doi: 10.1111/tra.12287. Epub 2015 May 6.
• During regulated intramembrane proteolysis (RIP) a membrane-spanning substrate protein is cleaved by an ectodomain sheddase and an intramembrane cleaving protease. A cytoplasmic intracellular domain (ICD) is liberated, which can migrate to the nucleus thereby influencing transcriptional regulation.
• PMID 25824657

Japanese Journal

• Expression and characterization of cathepsin B from tsetse (Glossina morsitans morsitans)

• Japanese Journal of Veterinary Research 61(4), 137-147, 2013-11
• NAID 120005350104

• 線維化疾患におけるエンドスタチンの役割と機能<br/>—抗線維化治療の可能性について—

• 日本臨床免疫学会会誌 36(6), 452-458, 2013
• NAID 130003383176

• Fc domain mediated self-association of an IgG1 monoclonal antibody under a low ionic strength condition(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)

• Journal of bioscience and bioengineering 112(4), 326-332, 2011-10
• NAID 110008761486

Related Links

• 特許 EP0317278A2 - Proteolytic fragments and synthetic ...

This purified proteolytic fragment of glycocalicin has been used to test its ability to block the binding of vWF to the GPIb of platelets. The 45 kDa fragment inhibited completely the ristocetin-mediated binding of vWF to platelets, i.e ...

• Endostatin, the Proteolytic Fragment of Collagen XVIII ...

Abstract Collagen XVIII is an important component of the extracellular matrix and is expressed in basement membranes. Its degradation results in the generation of endostatin claimed to possess antiangiogenic ...

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関連記事	「proteolytic」「fragment」

「proteolytic」

　　[★]

• タンパク分解性の、タンパク分解の、タンパク質分解の

関

protein degradation、proteolyses、proteolysis、proteolytic degradation、proteolytically、proteolyze

　

「fragment」

　　[★]

• n.

• 断片、破片、フラグメント

• v.

• 断片化する、細分化する

関

fragmentation、piece、shred、sliver、splinter、subdivision