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1. ペリツェウス・メルツバッハー病 pelizaeus merzbacher disease
2. 遺伝性痙性対麻痺 hereditary spastic paraplegia
3. 多発性硬化症の病態および疫学 pathogenesis and epidemiology of multiple sclerosis
4. 赤血球水分量の制御 control of red blood cell hydration
5. 小児における急性散在性脳脊髄炎：病因、臨床的特徴、および診断 acute disseminated encephalomyelitis in children pathogenesis clinical features and diagnosis

English Journal

IFN-β Facilitates Neuroantigen-Dependent Induction of CD25+ FOXP3+ Regulatory T Cells That Suppress Experimental Autoimmune Encephalomyelitis.

Wang D1, Ghosh D1, Islam SM1, Moorman CD1, Thomason AE1, Wilkinson DS1, Mannie MD2.
Journal of immunology (Baltimore, Md. : 1950).J Immunol.2016 Sep 12. pii: 1500411. [Epub ahead of print]
This study introduces a flexible format for tolerogenic vaccination that incorporates IFN-β and neuroantigen (NAg) in the Alum adjuvant. Tolerogenic vaccination required all three components, IFN-β, NAg, and Alum, for inhibition of experimental autoimmune encephalomyelitis (EAE) and induction of t
PMID 27619998

Sodium Benzoate, a Food Additive and a Metabolite of Cinnamon, Enriches Regulatory T Cells via STAT6-Mediated Upregulation of TGF-β.

Kundu M1, Mondal S1, Roy A1, Martinson JL2, Pahan K3.
Journal of immunology (Baltimore, Md. : 1950).J Immunol.2016 Sep 7. pii: 1501628. [Epub ahead of print]
Upregulation and/or maintenance of regulatory T cells (Tregs) during autoimmune insults may have therapeutic efficacy in autoimmune diseases. Earlier we have reported that sodium benzoate (NaB), a metabolite of cinnamon and a Food and Drug Administration-approved drug against urea cycle disorders, u
PMID 27605008

Molinaro R1, Corbo C1,2,3, Martinez JO1, Taraballi F1,4, Evangelopoulos M1, Minardi S1, Yazdi IK1, Zhao P5, De Rosa E1, Sherman MB6, De Vita A7, Toledano Furman NE1, Wang X1, Parodi A1,3, Tasciotti E1,8.
Nature materials.Nat Mater.2016 Sep;15(9):1037-46. doi: 10.1038/nmat4644. Epub 2016 May 23.
A multitude of micro- and nanoparticles have been developed to improve the delivery of systemically administered pharmaceuticals, which are subject to a number of biological barriers that limit their optimal biodistribution. Bioinspired drug-delivery carriers formulated by bottom-up or top-down stra
PMID 27213956

TAKANASHI Jun-ichi
Magnetic Resonance in Medical Sciences 14(2), 85-91, 2015
Proton magnetic resonance spectroscopy (MRS) allows the noninvasive exploration of tissue metabolism in vivo, providing neurophysiological and neurochemical information. N-acetylaspartate (NAA) is gen …
NAID 130005069922

TAKANASHI Jun-ichi
Magnetic Resonance in Medical Sciences advpub(0), 2015
Proton magnetic resonance spectroscopy (MRS) allows the noninvasive exploration of tissue metabolism in vivo, providing neurophysiological and neurochemical information. N-acetylaspartate (NAA) is gen …
NAID 130005063587