WordNet

control consisting of a mechanical device for controlling the flow of a fluid
device in a brass wind instrument for varying the length of the air column to alter the pitch of a tone
one of the paired hinged shells of certain molluscs and of brachiopods
the entire one-piece shell of a snail and certain other molluscs
a structure in a hollow organ (like the heart) with a flap to insure one-way flow of fluid through it
the branch of medicine dealing with the production and use of artificial body parts
of or relating to the heart; "cardiac arrest"
relating to or serving as a prosthesis
of or relating to prosthetics
the opening into the stomach and that part of the stomach connected to the esophagus

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1. 人工心臓弁のある患者における抗血栓療法 antithrombotic therapy in patients with prosthetic heart valves
2. 人工心臓弁のある患者のマネージメント management of patients with prosthetic heart valves
3. 人工心臓弁の合併症 complications of prosthetic heart valves
4. 心臓人工弁の心エコー評価 echocardiographic evaluation of prosthetic heart valves
5. 人工弁心内膜炎の疫学、臨床症状、および診断 epidemiology clinical manifestations and diagnosis of prosthetic valve endocarditis

Effects of fluid flow shear rate and surface roughness on the calcification of polymeric heart valve leaflet.

Boloori Zadeh P, Corbett SC, Nayeb-Hashemi H.SourceDepartment of Mechanical and Industrial Engineering, Northeastern University, 334 Snell Engineering Center, 360 Huntington Avenue, Boston, MA 02115-5000, USA.
Materials science & engineering. C, Materials for biological applications.Mater Sci Eng C Mater Biol Appl.2013 Jul 1;33(5):2770-5. doi: 10.1016/j.msec.2013.02.042. Epub 2013 Mar 1.
Surface defects, blood flow shear rates and mechanical stresses are contributing factors in the calcification process of polymeric devices exposed to the blood flow. A number of experiments were performed to evaluate the effect of surface defects such as roughness and cracks and flow shear rate on t
PMID 23623095

Biçer Yeşilay A, Kaya Z, Demirbağ R.SourceDepartment of Cardiology, Harran University Faculty of Medicine, Şanlıurfa, Turkey. asubicer@yahoo.com.
Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır.Turk Kardiyol Dern Ars.2013 Jul;41(4):354-63. doi: 10.5543/tkda.2013.35219.
All prosthetic valves are at least mildly stenotic and have relatively high transvalvular pressure gradients that can be observed despite normal prosthesis function. Such gradients may be due to a mismatch between prosthesis effective orifice area (EOA) and patient's body size. Valve prosthesis-pati
PMID 23760127

Bloodstream Infections Occurring in Patients With Percutaneously Implanted Bioprosthetic Pulmonary Valve: A Single-center Experience.

Buber J, Bergersen L, Lock JE, Gauvreau K, Esch JJ, Landzberg MJ, Valente AM, Sandora TJ, Marshall AC.SourceDepartment of Cardiology and the Division of Infectious Diseases, Departments of Medicine and Laboratory Medicine, Boston Children's Hospital, Boston, MA.
Circulation. Cardiovascular interventions.Circ Cardiovasc Interv.2013 Jun 11. [Epub ahead of print]
BACKGROUND: PERCUTANEOUS PULMONARY VALVE IMPLANTATION USING A STENT-BASED BIOPROSTHETIC VALVE PROVIDES AN ALTERNATIVE TO SURGERY IN SELECT PATIENTS. SYSTEMIC INFECTIONS IN MELODY VALVEIMPLANTED PATIENTS WITH AND WITHOUT IDENTIFIED VALVE INVOLVEMENT HAVE BEEN REPORTED, YET THE INCIDENCE IS UNKNOWN, A
PMID 23756696

Long-Term Clinical Outcomes of the On-X Mechanical Prosthetic Valve in the Aortic or Mitral Position　― A Single-Center Experience of up to 20 Years' Follow up ―

Kim Ji Seong,Kang Yoonjin,Sohn Suk Ho,Hwang Ho Young,Choi Jae Woong,Kim Kyung Hwan
Circulation Journal 85(7), 1042-1049, 2021
… t;p>Background:This study evaluated the long-term outcomes for up to 20 years after On-X mechanical valve implantation in the left side of the heart.Methods and Results:Between 1999 and 2015, 861 patients (mean age=51.6±10.9 years) who underwent prosthetic valve replacement using the On-X valve in the aortic or mitral position were enrolled (aortic=344, mitral=325, …
NAID 130008056904

Usefulness of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Diagnosis of Infective Endocarditis in Patients With Adult Congenital Heart Disease

Ishikita Ayako,Shiose Akira,Tsutsui Hiroyuki,Sakamoto Ichiro,Yamamura Kenichiro,Umemoto Shintaro,Nagata Hazumu,Kitamura Yoshiyuki,Yamasaki Yuzo,Sonoda Hiromichi,Tatewaki Hideki
Circulation Journal, 2021
… 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) has shown good diagnostic performance in prosthetic valve IE. … A negative 18F-FDG PET/CT (n=7, 39%) assessment was associated with a native valve IE (71% vs. 0%). …
NAID 130008014438

Effect of Treprostinil on the Early Postoperative Prognosis of Patients with Severe Left Heart Valvular Disease Combined with Severe Pulmonary Hypertension

Huang Shu-Ting,Xu Ning,Sun Kai-Peng,Chen Qiang,Cao Hua
Annals of Thoracic and Cardiovascular Surgery 27(1), 18-24, 2021
… Objective: To investigate the effect of treprostinil on the early postoperative prognosis of patients with severe left heart valvular disease combined with severe pulmonary hypertension (PAH).Methods: A retrospective study including 55 patients with severe left heart valvular disease combined with severe PAH who underwent left heart valve replacement in our hospital between January 2019 and May 2019 was conducted. …
NAID 130007988466

	機械弁	生体弁
種類	二様弁	1. 異種生体弁(ブタ大動脈弁、牛心膜弁) 2. 同種生体弁(大動脈弁置換術のみ) 　→ヒト大動脈弁、自己肺動脈弁
利点	耐久性(10年以上)	・抗血栓療法が不要・自然な弁機能
欠点	血栓予防のために生涯ワーファリンの服用が必要	10年以下(再手術を要する)
適応	普通は機械弁を使用	1. 出産希望 2. 出血性疾患がある症例 3. 小児(自己肺動脈弁)

人工弁(機械弁)は10年以上もつ耐久性があるというメリットがあるが、一方で弁に血栓が形成されないよう生涯にわたって抗血栓薬を服用する必要がある。生体弁は異種生体弁(ブタ大動脈弁、ウシ心膜弁)と同種生体弁(ヒト大動脈弁、自己肺動脈弁)があるが、いずれも抗血栓薬の服用が不要であるというメリットがあり、これは出産を希望している女性、小児、出血性疾患がある症例においては良い適応となる。一方で、耐久性に問題があり、10年を超えると弁機能不全となり交換を要するというデメリットがある。