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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/09 21:16:59」(JST)

Propamidine is an antiseptic and disinfectant.

Propamidine isethionate, the salt of propamidine with isethionic acid, is used in the treatment of Acanthamoeba infection.^[1]

References

^ Perrine D, Chenu JP, Georges P, Lancelot JC, Saturnino C, Robba M (February 1995). "Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga". Antimicrob. Agents Chemother. 39 (2): 339–42. doi:10.1128/aac.39.2.339. PMC 162538. PMID 7726493.

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Treatment of Acanthamoeba neurotrophic corneal ulcer with topical matrix therapy.

Mateo A1, Abadía B2, Calvo P1, Minguez E3, Pablo L1, Del Castillo JM4.
Journal of ophthalmic inflammation and infection.J Ophthalmic Inflamm Infect.2015 Jun 21;5:18. doi: 10.1186/s12348-015-0048-x. eCollection 2015.
BACKGROUND: This study was done to evaluate the visual and anatomical outcomes of topical regenerating agents as a novel therapy for neutrophic corneal ulcer (NCU) secondary to acanthamoeba infection.FINDINGS: A 20-year-old woman with a history of contact lens wear was referred to our hospital for k
PMID 26101555

Bouheraoua N1, Labbé A2, Chaumeil C3, Liang Q4, Laroche L5, Borderie V5.
Journal français d'ophtalmologie.J Fr Ophtalmol.2014 Oct;37(8):640-52. doi: 10.1016/j.jfo.2014.05.004. Epub 2014 Aug 29.
Early diagnosis and appropriate therapy are key elements for a good prognosis in Acanthamoeba keratitis (AK). AK should be considered in any case of corneal trauma complicated by exposure to soil or contaminated water, and in all contact lens (CL) wearers. A presumptive diagnosis of AK can be made c
PMID 25169145

Sunada A1, Kimura K2, Nishi I2, Toyokawa M2, Ueda A2, Sakata T2, Suzuki T3, Inoue Y4, Ohashi Y3, Asari S5, Iwatani Y3.
Ophthalmology.Ophthalmology.2014 Oct;121(10):2059-65. doi: 10.1016/j.ophtha.2014.04.013. Epub 2014 May 29.
PURPOSE: To evaluate the effectiveness of topical agents for the treatment of Acanthamoeba keratitis (AK).DESIGN: Laboratory research.PARTICIPANTS: Fifty-six Acanthamoeba isolates from 56 patients with clinically proven AK were studied.METHODS: The effectiveness of 7 agents against Acanthamoeba cyst
PMID 24880905

Kupffer cell depletion by liposome-delivered drugs : comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid

Kupffer cell depletion by liposome-delivered drugs : comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid

Combined treatment of Acanthamoeba keratitis with propamidine, neomycin, andpolyhexamethylene biguanide

拡張検索	「dibrompropamidine」

Propamidine
Names
	IUPAC name 4,4'-[propane-1,3-diylbis(oxy)]dibenzenecarboximidamide
Identifiers
CAS Number	104-32-5 ; 140-63-6 (isethionate)
ChEBI	CHEBI:87462
ChEMBL	ChEMBL23013
ChemSpider	58475
Jmol 3D image	Interactive graph
PubChem	64949
UNII	G20G12V769
	InChI InChI=1S/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21) Key: WTFXJFJYEJZMFO-UHFFFAOYSA-N ; InChI=1/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21) Key: WTFXJFJYEJZMFO-UHFFFAOYAO ;
	SMILES O(c1ccc(cc1)C(=[N@H])N)CCCOc2ccc(C(=[N@H])N)cc2 ;
Properties
Chemical formula	C17H20N4O2
Molar mass	312.37 g/mol
Pharmacology
ATC code	D08AC03 (WHO) S01AX15
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references