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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/21 20:37:36」(JST)

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  • Factors predisposing to ventricular proarrhythmia during antiarrhythmic drug therapy for atrial fibrillation in patients with structurally normal heart.
  • Lin CY1, Lin YJ1, Lo LW1, Chen YY2, Chong E3, Chang SL1, Chung FP1, Chao TF1, Hu YF1, Tuan TC1, Liao JN1, Chang Y1, Chien KL4, Chiou CW1, Chen SA5.
  • Heart rhythm : the official journal of the Heart Rhythm Society.Heart Rhythm.2015 Jul;12(7):1490-500. doi: 10.1016/j.hrthm.2015.04.018. Epub 2015 Apr 15.
  • BACKGROUND: Ventricular arrhythmia (VA) can occur during propafenone therapy in atrial fibrillation (AF) patients with structurally normal heart.OBJECTIVE: The purpose of this study was to evaluate the incidence and characteristics of propafenone-associated VAs in AF patients with structurally norma
  • PMID 25889809
  • Current Antiarrhythmic Therapy for Nonvalvular Atrial Fibrillation in Spain. Data From the FANTASIIA Registry.
  • Roldán Rabadán I1, Anguita Sánchez M2, Marín F3, Quesada MA4, Camacho Siles J4, Peinado R5, Bertomeu V6, Cequier Fillat Á7, Badimón L8, Muñiz J9; FANTASIIA study researchers.
  • Revista espanola de cardiologia (English ed.).Rev Esp Cardiol (Engl Ed).2015 Jun 17. pii: S1885-5857(15)00171-1. doi: 10.1016/j.rec.2015.03.004. [Epub ahead of print]
  • INTRODUCTION AND OBJECTIVES: Recently, there have been many developments in the management of nonvalvular atrial fibrillation, antiarrhythmic and anticoagulant therapy, and nonpharmacological treatment, but these developments are not applied immediately in clinical practice. The aim of this study wa
  • PMID 26093482
  • Propafenone shows class Ic and class II antiarrhythmic effects.
  • Stoschitzky K1, Stoschitzky G2, Lercher P2, Brussee H2, Lamprecht G3, Lindner W3.
  • Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.Europace.2015 Jun 7. pii: euv195. [Epub ahead of print]
  • AIMS: Propafenone is a well-known Class Ic antiarrhythmic agent. It has the typical chemical structure of a beta-blocker, but human studies on its beta-blocking effects revealed conflicting results.METHODS AND RESULTS: Twelve healthy males received single oral doses of 600 mg propafenone and placebo
  • PMID 26056191


  • Arrhythmia Pharmacogenomics
  • M. Roden Dan
  • Journal of Arrhythmia 27(Supplement), SS5_1, 2011
  • … Examples in cardiovascular therapy include polymorphisms in the drug metabolizing enzymes CYP2D6 contributing to variable propafenone or metoprolol responses or CYP2C19 contributing to variable clopidogrel responses; …
  • NAID 130002130114
  • Efficacy of Antiarrhythmic Drugs for Atrial Fibrillation Is Differently Dependent on Left Atrial Remodeling
  • Won Hoyoun,Jin Hwang Hye,Shim Jaemin,Uhm Jae-Sun,Joung Boyoung,Pak Hui-Nam,Lee Moon-Hyoung
  • Journal of Arrhythmia 27(Supplement), OP20_3, 2011
  • … flecainide, n=336 or propafenone, n=54) or amiodarone (n=155), were analyzed. …
  • NAID 130002129862


Propafenone (pron.: /proʊˈpæfɨnoʊn/ proh-PAF-i-nohn; brand name Rythmol SR or Rytmonorm) is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.
Features information about dosage, usage, warnings, and side effects.



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