a rope fitted with a hook and used for towing a gun carriage
a form of psychological torture inflicted by questioning the victim for hours
lengthen or extend in duration or space; "We sustained the diplomatic negotiations as long as possible"; "prolong the treatment of the patient"; "keep up the good work" (同)sustain, keep_up
lengthen in time; cause to be or last longer; "We prolonged our stay"; "She extended her visit by another day"; "The meeting was drawn out until midnight" (同)protract, extend, draw_out
PrepTutorEJDIC
(時間的・空間的に)‥‘を'『延ばす』,『延長する』
長引く,長期の
English Journal
Mechanisms, indications and results of salvage systemic therapy for sporadic and von Hippel-Lindau related hemangioblastomas of the central nervous system.
Capitanio JF1, Mazza E, Motta M, Mortini P, Reni M.Author information 1Department of Neurosurgery and Radiosurgery, IRCCS San Raffaele Scientific Institute, Milan, Italy. jody.capitanio@gmail.comAbstractHemangioblastomas (HBs) are rare indolent vascular tumors that may occur sporadically or in association with von Hippel-Lindau (VHL) disease. Total neurosurgical resection is the standard upfront approach providing long-term tumor control. At time of tumor recurrence, second surgery, radiosurgery or radiotherapy are the main therapeutic strategies. Limited information is available on the role of pharmacological strategies. Anti-angiogenic agents, particularly multitarget tyrosine kinase inhibitors (semaxanib, sunitinib, vatalanib), thalidomide and interferon alfa-2a are currently the most widely studied strategies to prolonge disease stability. Salvage therapy with anti-angiogenetic drugs may be of benefit in some patients who are not suitable for surgery, radiosurgery or radiotherapy, with progressive or recurrent hemangioblastoma especially those located in retina, since anti-angiogenetic therapy may delay tumor progression. This strategy warrants prospective evaluation in a clinical trial.
Critical reviews in oncology/hematology.Crit Rev Oncol Hematol.2013 Apr;86(1):69-84. doi: 10.1016/j.critrevonc.2012.10.001. Epub 2012 Nov 11.
Hemangioblastomas (HBs) are rare indolent vascular tumors that may occur sporadically or in association with von Hippel-Lindau (VHL) disease. Total neurosurgical resection is the standard upfront approach providing long-term tumor control. At time of tumor recurrence, second surgery, radiosurgery or
[Transarterial chemoembolisation in hepatocellular carcinoma].
Petersen J1, Henninger B, Glodny B, Jaschke W.Author information 1Department Radiologie, Medizinische Universität Innsbruck, Anichstraße 35, 6020 Innsbruck, Österreich. johannes.petersen@i-med.ac.atAbstractHepatocellular carcinoma is one of the most common cause of cancer related death. The present review gives an overview on the loco-regional therapy performed by transarterial chemoembolization (TACE).TACE combines two different therapeutic approaches. First, application of chemotherapeutic agents into tumor's feeding vessels and second, selectively de-arterialization by different particle embolization applicated during angiography. Different chemoembolization agents and techniques are described. The methode is save and less invasive. Side effects range from the postembolization syndrom with nausea, vomiting, fever and abdominal pain up to hepatic insufficiency, which is very rare.The aim of the therapy is control clinical symptoms, prolonge progression free survival, stabilize quality of life and survival. Further indications are bridging therapy prior liver transplantation and TACE is used as a neoadjuvant therapy.Thus, TACE plays a role in the therapy of HCC and indication should be tailored to the individual patient's condition by an interdisciplinary tumor board.
Wiener medizinische Wochenschrift (1946).Wien Med Wochenschr.2013 Mar;163(5-6):123-7. doi: 10.1007/s10354-013-0180-x. Epub 2013 Feb 15.
Hepatocellular carcinoma is one of the most common cause of cancer related death. The present review gives an overview on the loco-regional therapy performed by transarterial chemoembolization (TACE).TACE combines two different therapeutic approaches. First, application of chemotherapeutic agents in
[Efficacy and safety of regimens of capecitabine-based chemotherapy in the treatment of advanced breast cancer].
Huang HY1, Jiang ZF, Wang T, Zhang SH, Bian L, Cao Y, Wu SK, Song ST.Author information 1Department of Breast Cancer, Academy of Military Medical Sciences, Beijing, China.AbstractOBJECTIVE: To evaluate retrospectively the efficacy and toxicity of capecitabine-based chemotherapy in the treatment of advanced breast cancer.
Zhonghua zhong liu za zhi [Chinese journal of oncology].Zhonghua Zhong Liu Za Zhi.2011 Nov;33(11):850-3.
OBJECTIVE: To evaluate retrospectively the efficacy and toxicity of capecitabine-based chemotherapy in the treatment of advanced breast cancer.METHODS: Three hundred and seventy-six patients with advanced breast cancer were treated with capecitabine-based chemotherapy regimens in our department from