出典: meddic

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/12/25 17:58:01」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.


  • Formation of the diuretic chlorazanil from the antimalarial drug proguanil-Implications for sports drug testing.
  • Thevis M1, Geyer H2, Thomas A2, Tretzel L2, Bailloux I3, Buisson C3, Lasne F3, Schaefer MS4, Kienbaum P4, Mueller-Stoever I5, Schänzer W2.
  • Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Nov 10;115:208-13. doi: 10.1016/j.jpba.2015.07.017. Epub 2015 Jul 22.
  • Chlorazanil (Ordipan, N-(4-chlorophenyl)-1,3,5-triazine-2,4-diamine) is a diuretic agent and as such prohibited in sport according to the regulations of the World Anti-Doping Agency (WADA). Despite its introduction into clinical practice in the late 1950s, the worldwide very first two adverse analyt
  • PMID 26226108
  • WITHDRAWN: Drugs for preventing malaria in travellers.
  • Jacquerioz FA1, Croft AM.
  • The Cochrane database of systematic reviews.Cochrane Database Syst Rev.2015 Oct 5;10:CD006491. [Epub ahead of print]
  • BACKGROUND: Malaria infects 10,000 to 30,000 international travellers each year. It can be prevented through anti-mosquito measures and drug prophylaxis. However, antimalaria drugs have adverse effects which are sometimes serious.OBJECTIVES: To compare the effects of currently used antimalaria dru
  • PMID 26436859
  • [13-year old girl with fever 6 months after returning from sub-Saharan Africa].
  • Erhardt J1, Frank M1.
  • Deutsche medizinische Wochenschrift (1946).Dtsch Med Wochenschr.2015 Oct;140(21):1614. doi: 10.1055/s-0041-103556. Epub 2015 Oct 21.
  • HISTORY AND ADMISSION FINDINGS: A 13-year-old girl presented with regular fevers, 6 months after a prolonged trip through Africa. The patient reported relapsing fevers at 48 hour intervals. Each febrile episode was followed by pronounced fatigue and a subsequent recovery back to her usual state of h
  • PMID 26488102


  • Prolonged administration of proguanil induces reproductive toxicity in male rats
  • Akinsomisoye Olumide Stephen,Raji Yinusa
  • Journal of toxicological sciences 36(5), 587-599, 2011-10-01
  • … The toxicity of proguanil was studied on reproductive activities in male rats using in vivo and in vitro methods. … Groups of ten to twelve-week-old rats were administered proguanil (2.9 mg/kg body weight) daily for 5 days and 6 weeks respectively. … Sertoli cells obtained from sixteen to eighteen day-old-rats were cultured and treated with 0.3 μM to 10 μM of proguanil for 5 days after which Sertoli cell viability and nuclei integrity were determined. …
  • NAID 10029481335
  • Influence of the Genetic Polymorphisms in the 5' Flanking and Exonic Regions of CYP2C19 on Proguanil Oxidation
  • SATYANARAYANA Chakradhara Rao Uppugunduri,DEVENDRAN Anichavezhi,JAYARAMAN Muthukumaran,MANNU Jayakanthan,MATHUR Premendu P.,GOPAL Shewade Deepak,RAJAGOPAL Krishnamoorthy,CHANDRASEKARAN Adithan
  • Drug metabolism and pharmacokinetics 24(6), 537-548, 2009-12-25
  • NAID 10027119696
  • Efficacy and safety of atovaquone-proguanil compared with mefloquine in the treatment of nonimmune patients with uncomplicated P. falciparum malaria in Japan
  • HITANI Akihiro,NAKAMURA Tetsuya,OHTOMO Hiroshi,NAWA Yukifumi,KIMURA Mikio
  • Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 12(5), 277-282, 2006-10-01
  • NAID 10018348283


Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. When taken, it is converted to the active metabolite cycloguanil. Proguanil is effective against sporozoites. Proguanil hydrochloride is marketed as Paludrine by ...
The drug combination atovaquone/proguanil (INNs, trade names Malarone, Malanil) is an antimalarial medication used in both the treatment and prevention of malaria, commercially available from GlaxoSmithKline since 2000. Atovaquone ...


Proguanil test kitFinished Formulation, Gastroenterological  Malarone Mefloquine Chloroquine ProguanilAtovaquone-ProguanilAtovacuona-Proguanil | Malaria Proguanil - Wikipedia, la enciclopedia








1user/password 20
2ミタゾラム 効果 16
3Jardine, A., Neville, P. J., Dent, C., Webster, C., & Lindsay, M. D. (2014). Ross River virus risk associated with dispersal of Aedes (Ochlerotatus) camptorhynchus (Thomson) from breeding habitat into surrounding residential areas: muddy lakes, Western Australia. American Journal of Tropical Medicineand Hygiene, 91(1), 101-108. doi:10.4269/ajtmh.13-0399 16
4化生 特徴 15
5多毛日本 12
61,1024,768,24 HTTP/1.1 8
7user/register 8
8ラクテック 8
9cefpodoxime proxetil BCS 8
10盲斑 7
111,320,568,24 HTTP/1.1 7
12日常生活自立度 6
13Salivary glands 5
14viraldeath解剖 5
15ルリッシュ症候群 5
16サイズの原理 筋電図 5
17メトロイリーゼ 4
18?mesterolon? Britain 4
19vitブラウザの1時間2.3時間を見る方法 4
20ハルトマン 4

1user/password 9
2医の倫理 国際網領 4
3ハルトマン 3
4ソルデム 3
5顔面失行 3
6動脈血柱反射 3
7ワレンベルグ症候群 3
8monnro-kou 3
9扁平コンジローマ 3
10サーモグラフィー 末梢循環障害 2
11化学性腹膜炎 2
12高カルシウム血症 2
13シンプソン徴候 2
14自動性 2
15眼球圧迫法 2
16ポイツイエーガー症候群 2
17albright 症候群 2
18心窩部痛 2
19シドフォビル 2
20強皮症 下部食道蠕動運動 2