WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

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1. 止血の概要 overview of hemostasis
2. 食物アレルゲンの分子機能 molecular features of food allergens
3. 抗リン脂質抗体症候群の発症機序 pathogenesis of antiphospholipid syndrome
4. 血管内皮機能および血栓溶解療法の基本的メカニズム vascular endothelial function and fundamental mechanisms of fibrinolysis thrombolysis
5. 悪性腫瘍に関連した凝固亢進状態の病因 pathogenesis of the hypercoagulable state associated with malignancy

Delicate Balance of Bleeding and Thrombosis in End-Stage Liver Disease and Liver Transplantation.

Saner FH, Gieseler RK, Akız H, Canbay A, Görlinger K.SourceDepartment of General, Visceral and Transplantation Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Digestion.Digestion.2013 Sep 5;88(3):135-144. [Epub ahead of print]
Liver transplantation in cirrhotic patients is accompanied by severe bleeding. Indeed, the first 100 recipients of liver allografts transplanted by Thomas E. Starzl died mainly by uncontrolled bleeding. Since then, much progress has been made as to the understanding of the pathophysiology and the tr
PMID 24008288

Clot lysis phenotype and response to recombinant factor VIIa in plasma of haemophilia A inhibitor patients.

Bakhtiari K, Kamphuisen PW, Mancuso ME, Hamulyak K, Schutgens RE, Santagostino E, Meijers JC.SourceDepartment of Experimental Vascular Medicine, Academic Medical Centre, Amsterdam, The Netherlands.
British journal of haematology.Br J Haematol.2013 Sep;162(6):827-35. doi: 10.1111/bjh.12470. Epub 2013 Jul 25.
Recombinant activated factor VII (rFVIIa) is a haemostatic agent that is used for the treatment of haemophilia A patients with inhibitors. However, clinical response to rFVIIa is variable and unpredictable with currently available assays. We investigated the anti-fibrinolytic effects of rFVIIa in re
PMID 23889493

Anti-β2GPI antibodies stimulate endothelial cell microparticle release via a non-muscle myosin II motor protein-dependent pathway.

Betapudi V, Lominadze G, Hsi L, Willard B, Wu M, McCrae KR.SourceDepartment of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, OH, United States;
Blood.Blood.2013 Aug 16. [Epub ahead of print]
The antiphospholipid syndrome is characterized by thrombosis and recurrent fetal loss in patients with antiphospholipid antibodies (APLA). Most pathogenic APLA are directed against β2-glycoprotein I (β2GPI), a plasma phospholipid binding protein. One mechanism by which circulating APLA/anti-β2GPI
PMID 23954892

Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface