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1. 肺外結核および粟粒結核の疫学および病理 epidemiology and pathology of extrapulmonary and miliary tuberculosis
2. 小児における結核 tuberculosis disease in children
3. 肺結核の臨床症状および評価 clinical manifestations and evaluation of pulmonary tuberculosis
4. 結核の疫学 epidemiology of tuberculosis
5. 結核の皮膚症状 cutaneous manifestations of tuberculosis

English Journal

Tuberculosis transmission among children and adolescents in schools and other congregate settings: a systematic review.

Schepisi MS, Motta I, Dore S, Costa C, Sotgiu G, Girardi E.
The new microbiologica. 2019 10;41(4)282-290.
Children, especially those aged <5 years, and adolescents are at increased risk of progression to active TB disease when infected. Management of childhood TB outbreaks is crucial for TB elimination especially in low burden countries. We searched the electronic databases MEDLINE-CINHAL-EMBASE up to J
PMID 30252926

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N, Delano K, Da Silva I, Davis J, Gallo C, Gardner M, Golas AJ, Guinn KM, Kennedy S, Korn R, McConnell JA, Moss CE, Murphy KC, Nietupski RM, Papavinasasundaram KG, Pinkham JT, Pino PA, Proulx MK, Ruecker N, Song N, Thompson M, Trujillo C, Wakabayashi S, Wallach JB, Watson C, Ioerger TR, Lander ES, Hubbard BK, Serrano-Wu MH, Ehrt S, Fitzgerald M, Rubin EJ, Sassetti CM, Schnappinger D, Hung DT.
Nature. 2019 Jun;().
New antibiotics are needed to combat rising levels of resistance, with new Mycobacterium tuberculosis (Mtb) drugs having the highest priority. However, conventional whole-cell and biochemical antibiotic screens have failed. Here we develop a strategy termed PROSPECT (primary screening of strains to
PMID 31217586

Cas9 conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond.

Roberts AW, Popov LM, Mitchell G, Ching KL, Licht DJ, Golovkine G, Barton GM, Cox JS.
eLife. 2019 Jun;8().
Macrophages play critical roles in immunity, development, tissue repair, and cancer, but studies of their function have been hampered by poorly-differentiated tumor cell lines and genetically-intractable primary cells. Here we report a facile system for genome editing in non-transformed macrophages
PMID 31204998