primary chronic adrenocortical insufficiency

原発性慢性副腎皮質機能低下症

WordNet

1. of first rank or importance or value; direct and immediate rather than secondary; "primary goals"; "a primary effect"; "primary sources"; "a primary interest"
2. a preliminary election where delegates or nominees are chosen (同)primary_election
3. one of the main flight feathers projecting along the outer edge of a birds wing (同)primary feather, primary quill
4. (astronomy) a celestial body (especially a star) relative to other objects in orbit around it
5. not derived from or reducible to something else; basic; "a primary instinct"
6. a lack of competence; "pointed out the insufficiencies in my report"; "juvenile offenses often reflect an inadequacy in the parents" (同)inadequacy
7. (pathology) inability of a bodily part or organ to function normally
8. lack of an adequate quantity or number; "the inadequacy of unemployment benefits" (同)inadequacy, deficiency
9. being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
10. of long duration; "chronic money problems" (同)continuing
11. habitual; "a chronic smoker" (同)inveterate
12. of or derived from the cortex of the adrenal glands

PrepTutorEJDIC

1. 『第一の』,『主要な』 / 『初期の』,『初等の』,初級の / 『根本的な』,基本的な,本来の,直接的な / 《名詞の前にのみ用いて》(回路・コイル・巻き・電流などが)一次の / 原色(三原色の一つ) / 《米》=primary election
2. 不十分な[点],不足;不適当,不向き
3. (病気が)長期にわたる,慢性の / 《名詞の前にのみ用いて》常習の,癖になった

UpToDate Contents

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• 1. 成人における副腎不全の診断 diagnosis of adrenal insufficiency in adults
• 2. 成人における副腎不全の臨床症状 clinical manifestations of adrenal insufficiency in adults
• 3. 小児における副腎不全の診断 diagnosis of adrenal insufficiency in children
• 4. 原発性副腎不全（アジソン病）の原因 causes of primary adrenal insufficiency addisons disease
• 5. 成人における副腎不全の治療 treatment of adrenal insufficiency in adults

English Journal

• Adrenocortical function in hypotensive patients with end stage renal disease.

• Arregger AL1, Cardoso EM2, Zucchini A3, Aguirre EC4, Elbert A5, Contreras LN6.
• Steroids.Steroids.2014 Jun;84:57-63. doi: 10.1016/j.steroids.2014.03.008. Epub 2014 Mar 28.
• BACKGROUND: Sustained hypotension among patients with end stage renal disease on dialysis (ESRDh) varies from 5.0% to 12.0%. Despite their role in the regulation of blood pressure (BP) corticoadrenal hormones have been poorly investigated.OBJECTIVES: This study aims to detect adrenal insufficiency i
• PMID 24686207

• X-linked adrenoleukodystrophy in women: a cross-sectional cohort study.

• Engelen M1, Barbier M, Dijkstra IM, Schür R, de Bie RM, Verhamme C, Dijkgraaf MG, Aubourg PA, Wanders RJ, van Geel BM, de Visser M, Poll-The BT, Kemp S.
• Brain : a journal of neurology.Brain.2014 Mar;137(Pt 3):693-706. doi: 10.1093/brain/awt361. Epub 2014 Jan 29.
• X-linked adrenoleukodystrophy is the most common peroxisomal disorder. The disease is caused by mutations in the ABCD1 gene that encodes the peroxisomal transporter of very long-chain fatty acids. A defect in the ABCD1 protein results in elevated levels of very long-chain fatty acids in plasma and t
• PMID 24480483

• Delay in diagnosis of adrenal insufficiency is a frequent cause of adrenal crisis.

• Papierska L1, Rabijewski M.
• International journal of endocrinology.Int J Endocrinol.2013;2013:482370. doi: 10.1155/2013/482370. Epub 2013 Jun 24.
• Delay of diagnosis of primary adrenal insufficiency (PAI) leads to adrenal crisis which is potentially lethal complication. The objective of our work was an assessment whether the establishment of diagnosis of adrenocortical insufficiency in Poland is so much delayed as assessed in the past. We have
• PMID 23864857

Related Links

• [Chronic adrenocortical insufficiency(primary, secondary ...

Publication » [Chronic adrenocortical insufficiency(primary, secondary)].. Article [Chronic adrenocortical insufficiency(primary, secondary)]. Keizo Ohnaka Ryoichi Takayanagi ...

• Addison's Disease – Primary Adrenal Insufficiency ...

Addison's disease – primary adrenal insufficiency Diseases of the adrenal cortex – Elite Treatment in Europe ENDOCRINOLOGY -2005 Adrenal insufficiency is acute ... Primary adrenocortical insufficiency is the result of tissue ...

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★リンクテーブル★

リンク元	「アジソン病」「原発性慢性副腎皮質機能低下症」
関連記事	「insufficiency」「primary」「adrenocortical」「chronic」

「アジソン病」

　　[★]

英

Addison disease

ラ

morbus Addisonii

関

原発性慢性副腎皮質機能低下症 primary chronic adrenocortical insufficiency、難病

副腎皮質からのステロイド分泌が低下
⇔ クッシング症候群

概念

• 難病に指定されている。

部分症

• 多腺性自己免疫症候群1型：HAM症候群
• 多腺性自己免疫症候群2型：シュミット症候群

症状

• 糖質コルチコイド欠乏：やせ、脱力、食欲不振、悪心・嘔吐、易疲労感、精神症状、低血糖、水利尿不全(ADHの拮抗不全となり水貯留？)、貧血
• 鉱質コルチコイド欠乏：
• 副腎アンドロゲン欠乏：

検査

• 血算：正球性貧血。白血球減少。好酸球増多、リンパ球増多　　←　　糖質コルチコイド#5. 抗炎症作用　　クッシング症候群の逆を考えればよい
• 免疫血清学的検査：抗副腎抗体
• 負荷試験

• ACTH連続刺激試験：血中コルチゾール・尿中17-OHCS →
• アンジオテンシンII負荷試験：血中アルドステロン →

参考

• 1. 副腎低形成(アジソン病) - 難病情報センター

http://www.nanbyou.or.jp/entry/206

• 2.

http://www.pediatric-world.com/asahikawa/fukujin/p06.html

uptodate

• . [charged] 患者情報：副腎不全（アジソン病） (患者向け詳細版) - uptodate [1]
• . [charged] 原発性副腎不全（アジソン病）の原因 - uptodate [2]
• . [charged] 成人における二次性および三次性副腎不全の原因 - uptodate [3]
• . [charged] 副腎不全におけるACTHに対する反応の評価 - uptodate [4]
• . [charged] 小児における原発性副腎不全の原因および臨床症状 - uptodate [5]
• . [charged] 小児における副腎不全の診断 - uptodate [6]
• . [charged] 小児における副腎不全の治療 - uptodate [7]
• . [charged] 成人における副腎不全の臨床症状 - uptodate [8]
• . [charged] 成人における副腎不全の診断 - uptodate [9]
• . [charged] 成人における副腎不全の治療 - uptodate [10]

「原発性慢性副腎皮質機能低下症」

　　[★]

英

primary chronic adrenocortical insufficiency

関

アジソン病

「insufficiency」

　　[★]

• n.

• 不全、不全症、機能不全、機能不全症、不足、不十分、(心臓)弁閉鎖不全、弁閉鎖不全症

関

dearth、deficient、deficit、dysfunction、failing、failure、hypofunction、imperfecta、in short、inadequate、incompetence、insufficient、insufficiently、lack、low、malfunction、paucity、poorly、regurgitation、scanty、scarce、scarcity、short、shortage、shortness、stun

　 　 　 　

「primary」

　　[★]

• adj.

• 一次の、第一次の、主要な、(化学)第一級の、一級の、初生の、(病名)原発性の、原発の、プライマリーの

関

cardinal、chief、first-order、foremost、main、mainly、major、master、primarily、principal、principally

　 　 　 　 　 　

「adrenocortical」

　　[★]

• 副腎皮質の、副腎皮質性の

関

adrenal cortex、adrenal cortical、adrenal cortices

　

「chronic」

　　[★]

• adj.

• 慢性の、慢性的な、慢性型の

関

chronically、chronicity