English Journal

A HaloTag-Based Small Molecule Microarray Screening Methodology with Increased Sensitivity and Multiplex Capabilities.

Noblin DJ, Page CM, Tae HS, Gareiss PC, Schneekloth JS, Crews CM.SourceDepartments of †Molecular Cellular and Developmental Biology, §Chemistry, and ∥Pharmacology, Yale University , 219 Prospect Street, New Haven, Connecticut 06511, United States.
ACS chemical biology.ACS Chem Biol.2012 Oct 11. [Epub ahead of print]
Small Molecule Microarrays (SMMs) represent a general platform for screening small molecule-protein interactions independent of functional inhibition of target proteins. In an effort to increase the scope and utility of SMMs, we have modified the SMM screening methodology to increase assay sensitivi
PMID 23013033

Science to practice: can macrophage infiltration serve as a surrogate marker for stem cell viability?

Bulte JW.SourceRussell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine 720 Rutland Ave, 217 Traylor, Baltimore, MD 21205, USA. jwmbulte@mri.jhu.edu
Radiology.Radiology.2012 Sep;264(3):619-20. doi: 10.1148/radiol.12121378.
Following in vivo prelabeling of host macrophages with ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles, it was shown that their magnetic resonance (MR) imaging–visible migration into knee implants of scaffolded adipose-derived stem cells (ADSCs) undergoing apoptosis can serve as a su
PMID 22919033

Japanese Journal

Determination of hepatic cysteinesulfinate decarboxylase activity in fish by means of OPA-prelabeling and reverse-phase high-performance liquid chromatographic separation