WordNet

any localized abnormal structural change in a bodily part
of or relating to a growth that is not malignant but is likely to become so if not treated

PrepTutorEJDIC

傷害,傷 / (体の組織や機能の)障害
前癌(がん)症状の

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/11/02 23:17:34」(JST)

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A precancerous condition or premalignant condition, sometimes called a potentially precancerous condition or potentially premalignant condition, is a state of disordered morphology of cells that is associated with an increased risk of cancer. If left untreated, these conditions may lead to cancer. Such conditions are usually either dysplasia or benign neoplasia (and the dividing line between those is sometimes blurry). Sometimes the term "precancer" is used to describe carcinoma in situ, which is a noninvasive cancer that has not progressed to an aggressive, invasive stage. Not all carcinoma in situ will progress to invasive disease.

Premalignant lesions are morphologically atypical tissue which appears abnormal under microscopic examination, and in which cancer is more likely to occur than in its apparently normal counterpart.

Examples of premalignant conditions include:

actinic keratosis^[1]
Barrett's esophagus
atrophic gastritis
ductal carcinoma in situ
dyskeratosis congenita
sideropenic dysphagia
lichen planus
oral submucous fibrosis
solar elastosis
cervical dysplasia
leukoplakia
erythroplakia

The term was coined in 1875 by Romanian physician Victor Babeş.

References

^ "Actinic Keratosis (A Precancerous Condition)". Retrieved 2009-03-03.

http://screening.iarc.fr/atlasoral_list.php?cat=A&lang=1

External links

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1. 子宮頚部および膣細胞診：結果の解釈 cervical and vaginal cytology interpretation of results
2. 環状皮膚病変が認められる患者に対するアプローチ approach to the patient with annular skin lesions
3. 口腔病変 oral lesions
4. ヒトパピローマウイルスのライフサイクル、自然史、および免疫学 the life cycle natural history and immunology of human papillomaviruses
5. 口腔異形成および頭頸部扁平上皮癌における化学予防およびスクリーニング chemoprevention and screening in oral dysplasia and squamous cell head and neck cancer

English Journal

Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1β/miR-101/Lin28B Signaling Pathway.

Wang CC1,2, Yuan JR1,2, Wang CF2,3, Yang N1,2, Chen J1,2, Liu D2, Song J2, Feng L2,4, Tan XB2,4, Jia XB2,4.
Integrative cancer therapies.Integr Cancer Ther.2017 Dec;16(4):505-515. doi: 10.1177/1534735416659358. Epub 2016 Aug 24.
PMID 27562754

High lifetime probability of screen-detected cervical abnormalities.

Pankakoski M1,2, Heinävaara S1,2, Sarkeala T1, Anttila A1.
Journal of medical screening.J Med Screen.2017 Dec;24(4):201-207. doi: 10.1177/0969141316685740. Epub 2017 Jan 10.
PMID 28073308

Oral leukoplakia and proliferative verrucous leukoplakia: a review for dental practitioners.

Staines K1, Rogers H1.
British dental journal.Br Dent J.2017 Nov 3. doi: 10.1038/sj.bdj.2017.881. [Epub ahead of print]
PMID 29097794

Japanese Journal

子宮頸癌におけるHPVウイルス発癌メカニズムをターゲットにした発癌予知バイオマーカーと治療薬開発に関する研究(シンポジウム2(腫瘍):子宮頸部腫瘍の病態に関する新知見-診断・治療法の開発に向けて-,第67回日本産科婦人科学会学術講演会講演要旨)

日本産科婦人科學會雜誌 67(11), 2524-2536, 2015-11-01
NAID 110010000754

ISP-3-4 HPV16E6 Mutations in Han and Uighur women with Cervical Carcinoma or Precancerous lesion in Xinjiang(Group 3 Oncology 3,IS Poster,International Session)

日本産科婦人科學會雜誌 67(2), 1010, 2015-02-01
NAID 110009942097

口腔白板症の臨床診断と病理組織診断の一致性についての検討:―安全な口腔白板症のレーザー治療の実現に向けて―

日本レーザー歯学会誌 26(3), 120-123, 2015
NAID 130005116303

Related Pictures

★リンクテーブル★

リンク元	「前がん病変」「precancerous change」
関連記事	「lesion」「precancerous」

「前がん病変」

Precancerous condition
	Micrograph of high grade squamous intraepithelial lesion, a precancerous condition of the uterine cervix. Pap stain.
Classification and external resources
MeSH	D011230
	[edit on Wikidata]