WordNet

any compound that contains water of crystallization
become hydrated and combine with water
cause to be hydrated; add water or moisture to; "hydrate your skin"
supply water or liquid to in order to maintain a healthy balance; "the bicyclists must be hydrated frequently"
small tubular solitary freshwater hydrozoan polyp
trouble that cannot be overcome by a single effort because of its many aspects or its persistent and pervasive quality; "we may be facing a hydra that defies any easy solution"
a complex consisting of an organic base in association with hydrogen chloride

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1. 成人における単極性大うつ病：刺激薬および stimulant-like drugsによる抗うつ薬の増強 unipolar major depression in adults augmentation of antidepressants with stimulants and stimulant like drugs
2. 成人におけるむずむず脚症候群／ウィリス・エクボム病および周期性四肢運動障害の治療 treatment of restless legs syndrome willis ekbom disease and periodic limb movement disorder in adults
3. パーキンソン病に対する神経保護療法 neuroprotective therapy for parkinson disease
4. パーキンソン病の薬理学的治療 pharmacologic treatment of parkinson disease
5. 多系統萎縮症：予後および治療 multiple system atrophy prognosis and treatment

Effects of a dopamine receptor agonist and atropine sulfate on absorption of valproic acid in rats.

Kameya H, Hokama N, Hobara N, Ohshiro S, Uno T.SourceDepartment of Hospital Pharmacy, Faculty of Medicine, University of the Ryukyus, Okinawa.
Biomedical research (Tokyo, Japan).Biomed Res.2009 Apr;30(2):101-6.
The aim of this study is to determine whether pramipexole hydrochloride hydrate (PHH) and atropine sulfate affect valproic acid (VPA) pharmacokinetics and to evaluate how plasma VPA concentrations are altered by different PHH administration routes. The following studies were conducted on rats: 1) ch
PMID 19420733

Bayés M, Rabasseda X, Prous JR.Sourcembayes@prous.com
Methods and findings in experimental and clinical pharmacology.Methods Find Exp Clin Pharmacol.2002 Sep;24(7):431-55.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.c
PMID 12428432

松木俊二,名取和一,小川幸司,松井隆,松隈京子,坂本慶,木村美由紀,神田英里,米納誠,伊藤一弥,鄭恩希,白源正成,入江伸
臨床薬理 45(4), 151-159, 2014
… The aims of the present study were (1) to determine the maximum tolerated doses of quetiapine and pramipexole when given to healthy Japanese male subjects using gradually increasing single doses; … For pramipexole, 18 participants received 0.125 mg in the first stage, and then received 0.25 mg, 0.375 mg, or 0.5 mg in the second stage in the same manner as quetiapine. … In the group receiving 0.5 mg of pramipexole, three mild and five moderate adverse events were reported from five subjects. …
NAID 130004679400

脇川健,藤田淳也,西平綾子
日本透析医学会雑誌 = Journal of Japanese Society for Dialysis Therapy 44(12), 1155-1161, 2011-12-28
一般人口におけるレストレスレッグス症候群（restless legs syndrome：RLS）の有病率は，欧米で5～10％，日本で2～5％と報告されているのに対し，透析患者におけるRLSの出現頻度は4.8～32.2％と，明らかに高い有病率の報告がなされている．だが，本邦で透析患者を対象とした疫学調査は少数しか報告されていない．本邦では，プラミペキソール塩酸塩水和物（以下，プラミペキソール）が20 …
NAID 10030389704