WordNet

happening or done after a surgical operation; "postoperative complications"; "postoperative care"
after the operation; "remove postoperatively"

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Preclinical therapeutic response of residual metastatic disease is distinct from its primary tumor of origin.

Day CP, Carter J, Bonomi C, Hollingshead M, Merlino G.SourceLaboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD.
International journal of cancer. Journal international du cancer.Int J Cancer.2012 Jan 1;130(1):190-9. doi: 10.1002/ijc.25978. Epub 2011 Apr 20.
Cancer-related deaths are caused principally by recurrence and metastasis arising from residual disease, whose therapeutic responses has been suggested to be substantially different from primary tumors. However, experimental animal models designed for evaluating the therapeutic responses of residual
PMID 21312195

Glycolysis inhibition by 2-deoxy-D: -glucose reverts the metastatic phenotype in vitro and in vivo.

Sottnik JL, Lori JC, Rose BJ, Thamm DH.SourceAnimal Cancer Center, Department of Clinical Sciences, Colorado State University, Fort Collins, CO, 80523-1620, USA.
Clinical & experimental metastasis.Clin Exp Metastasis.2011 Dec;28(8):865-75. Epub 2011 Aug 14.
Metastasis is the primary cause of death from many tumors, and novel anti-metastatic therapies are necessary. Recently, we showed that metastatic tumors down-regulate key oxidative phosphorylation (OXPHOS) genes in favor of glycolysis, a further enhancement of the Warburg effect. Therefore, we sough
PMID 21842413

小貫建一郎/正田純一/川本徹/有泉俊一/山本雅一
東京女子医科大学雑誌 82(2), 62-69, 2012-04-25
【目的】癌細胞表面の糖鎖構造はその悪性挙動に深く関与する.糖転移酵素GnT-Vは,ノックアウトマウスの解析結果より,癌の増殖・転移に必須の分子であることが証明されており、様々な癌種において生物学的悪性度との関連性が報告されている.以前我々は,pT2胆嚢癌(GBC)のGnT-V陽性例において、術後遠隔臓器転移再発が多く、陰性例と比較し有意に予後不良であることを報告した.しかし、他の胆道癌に関してのG …
NAID 110009004320