関: reversible posterior leukoencephalopathy syndrome

WordNet

located at or near or behind a part or near the end of a structure
a pattern of symptoms indicative of some disease
a complex of concurrent things; "every word has a syndrome of meanings"

PrepTutorEJDIC

《名詞の前にのみ用いて》(生物学的に,位置が)後ろの,後部の / (時間・順序が)後の;(…より)後の《+『to』+『名』》(later) / しり(buttocks)
(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/02/03 09:40:11」(JST)

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Posterior reversible encephalopathy syndrome (PRES), also known as reversible posterior leukoencephalopathy syndrome (RPLS), is a syndrome characterized by headache, confusion, seizures and visual loss. It may occur due to a number of causes, predominantly malignant hypertension, eclampsia and some medical treatments. On magnetic resonance imaging (MRI) of the brain, areas of edema (swelling) are seen. The symptoms tend to resolve after a period of time, although visual changes sometimes remain.^[1]^[2] It was first described in 1996.^[3]

Causes

PRES occurs due to the use of drugs like tacrolimus and cyclosporine, hence it may occur in people who have undergone an organ transplant, in which these drugs may be used to suppress transplant rejection. It also occurs due to eclampsia, severe high blood pressure, dramatic changes in blood pressure, and hypercalcemia. Low magnesium levels can augment PRES.^{[citation needed]}

Diagnosis

The diagnosis is typically made on magnetic resonance imaging of the brain; this may show hyperintensities on T₂-weighed imaging. Three different patterns have been described on MRI imaging.^[4] Cerebral angiography may provide a more definite diagnosis.^{[citation needed]}

Treatment

The treatment of PRES depends on the underlying cause. For instance, if the main problem is high blood pressure, blood pressure control will accelerate the resolution of the abnormalities. If the likely cause is medication, the withdrawal of the drug in question is needed.^[5]

References

^ Garg RK (January 2001). "Posterior leukoencephalopathy syndrome". Postgrad Med J 77 (903): 24–8. doi:10.1136/pmj.77.903.24. PMC 1741870. PMID 11123390. http://pmj.bmj.com/cgi/content/full/77/903/24.
^ Pula JH, Eggenberger E (November 2008). "Posterior reversible encephalopathy syndrome". Curr Opin Ophthalmol 19 (6): 479–84. doi:10.1097/ICU.0b013e3283129746. PMID 18854692.
^ Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin M, Lamy C, Mas J, Caplan L (1996). "A reversible posterior leukoencephalopathy syndrome.". N Engl J Med 334 (8): 494–500. doi:10.1056/NEJM199602223340803. PMID 8559202.
^ Peter P, George A. Posterior reversible encephalopathy syndrome and the pediatric population. J Pediatr Neurosci 2012;7:136-8.
^ Pedraza R, Marik PE, Varon J (November 2009). Posterior Reversible Encephalopathy Syndrome: A Review. Crit Care & Shock 12:135-143. http://www.criticalcareshock.org/files/Review%20-%20Posterior%20Reversible%20Encephalopathy%20Syndrome-%20A%20Review.pdf

UpToDate Contents

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1. 可逆性後白質脳症症候群 reversible posterior leukoencephalopathy syndrome
2. プラチナベースの化学療法の神経学的合併症の概要 overview of neurologic complications of platinum based chemotherapy
3. 分子標的薬である血管新生阻害剤の毒性：心血管系以外への影響 toxicity of molecularly targeted antiangiogenic agents non cardiovascular effects
4. 可逆性脳血管攣縮症候群 reversible cerebral vasoconstriction syndromes
5. 妊娠中および周産期の重症疾患 critical illness during pregnancy and the peripartum period

English Journal

Reversible posterior leukoencephalopathy syndrome of bilateral thalamus in acute lymphoblastic leukemia.

Kamezaki M, Kakimoto T, Takeuchi T, Akuta K, Kasahara H, Yamamoto K, Ujiie H, Sugahara H, Nishinaka K, Udaka F, Sakoda H.SourceDepartment of Hematology.
Leukemia & lymphoma.Leuk Lymphoma.2012 Oct;53(10):2083-4. Epub 2012 May 9.
PMID 22397315

Reversible posterior leukoencephalopathy syndrome associated with concurrent bevacizumab, gemcitabine, and oxaliplatin for cholangiocarcinoma.

Chang Y, Mbeo G, Littman SJ.SourceDepartment of Medicine, Internal Medicine Residency Program, AtlantiCare Regional Medical Center, 1925 Pacific Avenue, Atlantic City, NJ, 08401, USA, yongenc@yahoo.com.
Journal of gastrointestinal cancer.J Gastrointest Cancer.2012 Sep;43(3):505-7.
INTRODUCTION: Reversible posterior leukoencephalopathy syndrome (RPLS) is a rare disorder characterized by altered mental status, seizure, hypertension, and symmetrical white matter edema (leukoencephalopathy) typically in the posterior cerebral hemispheres on brain imaging. It is often linked to ce
PMID 21556724

Japanese Journal

Reversible Cerebral Vasoconstriction Syndrome Presenting as Subarachnoid Hemorrhage, Reversible Posterior Leukoencephalopathy, and Cerebral Infarction

Noda Kazuyuki,Fukae Jiro,Fujishima Kenji,Mori Kentaro,Urabe Takao,Hattori Nobutaka,Okuma Yasuyuki
Internal Medicine 50(11), 1227-1233, 2011
… Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by acute severe headache with or without additional neurological symptoms and reversible cerebral vasoconstriction. … We report a severe case of a 53-year-old woman with RCVS having an unruptured cerebral aneurysm and presenting as cortical subarachnoid hemorrhage, reversible posterior leukoencephalopathy syndrome, and cerebral infarction. …
NAID 130000770477

Apparent diffusion coefficient map based on diffusion-weighted magnetic resonance imaging is useful in diagnosing the brainstem variant of reversible posterior leukoencephalopathy syndrome with uremia

KATANO Kenichi,KAKUCHI Yasushi,NAKASHIMA Akikatsu,NAKAHAMA Katsuyuki,KAWANO Mitsuhiro
Clinical and experimental nephrology 14(5), 479-482, 2010-10-01
NAID 10027707317

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★リンクテーブル★

リンク元	「後部白質脳症症候群」
拡張検索	「reversible posterior leukoencephalopathy syndrome」
関連記事	「posterior」「syndrome」

「後部白質脳症症候群」

Posterior reversible encephalopathy syndrome
	Classification and external resources
	; Posterior reversible encephalopathy syndrome visible on magnetic resonance imaging as multiple cortico-subcortical areas of T2-weighted hyperintense (white) signal involving the occipital and parietal lobes bilaterally and pons.
ICD-10	G93.49
ICD-9	348.39
DiseasesDB	10460
MeSH	D054038

　　[★]

英: posterior leukoencephalopathy syndrome
関: 可逆性後白質脳症症候群

「reversible posterior leukoencephalopathy syndrome」

　　[★]

可逆性後白質脳症症候群

関: posterior leukoencephalopathy syndrome

「posterior」

　　[★]

adj.

後側の、後方の、後の

関: after、afterward、afterwards、backward、behind、following、late、post、posteriorly、subsequent

「syndrome」

　　[★]

n.

症候群

[Garg-1] Garg RK (January 2001). "Posterior leukoencephalopathy syndrome". Postgrad Med J 77 (903): 24–8. doi:10.1136/pmj.77.903.24. PMC 1741870. PMID 11123390. http://pmj.bmj.com/cgi/content/full/77/903/24.

[2] Pula JH, Eggenberger E (November 2008). "Posterior reversible encephalopathy syndrome". Curr Opin Ophthalmol 19 (6): 479–84. doi:10.1097/ICU.0b013e3283129746. PMID 18854692.

[Hinchey-3] Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin M, Lamy C, Mas J, Caplan L (1996). "A reversible posterior leukoencephalopathy syndrome.". N Engl J Med 334 (8): 494–500. doi:10.1056/NEJM199602223340803. PMID 8559202.

[4] Peter P, George A. Posterior reversible encephalopathy syndrome and the pediatric population. J Pediatr Neurosci 2012;7:136-8.

[5] Pedraza R, Marik PE, Varon J (November 2009). Posterior Reversible Encephalopathy Syndrome: A Review. Crit Care & Shock 12:135-143. http://www.criticalcareshock.org/files/Review%20-%20Posterior%20Reversible%20Encephalopathy%20Syndrome-%20A%20Review.pdf

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案内

posterior leukoencephalopathy syndrome