WordNet

any of several plants of the genus Hepatica having three-lobed leaves and white or pinkish flowers in early spring; of moist and mossy subalpine woodland areas of north temperate regions (同)liverleaf
a common liverwort (同)Marchantia polymorpha
pertaining to or affecting the liver; "hepatic ducts"; "hepatic cirrhosis"
a genetic abnormality of metabolism causing abdominal pains and mental confusion

PrepTutorEJDIC

ユキワリソウ(薄紫・白などの花を咲かせるキンポウゲ科の植物)
肝臓の;肝臓にきく,肝臓のような色の

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1. ポルフィリン症：概要 porphyrias an overview
2. 急性間欠性ポルフィリン症のマネージメントおよび予後 management and prognosis of acute intermittent porphyria
3. 異型ポルフィリン症 variegate porphyria
4. 晩発性皮膚ポルフィリン症および肝骨髄性ポルフィリン症：臨床的特徴および診断 porphyria cutanea tarda and hepatoerythropoietic porphyria clinical manifestations and diagnosis
5. ALA脱水酵素欠損性ポルフィリン症 ala dehydratase porphyria

English Journal

[Porphyria acuta hepatica intermittens].

Dzanković FF, Macić-Dzanković AS.SourceKlinika za kostanu hirurgiju, Klinicki centar Univerziteta u Sarajevu.
Medicinski arhiv.Med Arh.2007;61(3):182-3.
It is case report forty years old woman was admitted at Clinic for abdominal surgery of Clinical center University of Sarajevo, than at Clinic for bone surgery because of general weakness, pain in legs and paraparesis lower extremities. Anamnestic data about earlier hospitalisation because of abdomi
PMID 18232285

[Acute porphyrias: problem of primary diagnosis in Russia and CIS countries].

Karpova IV, Pustovoĭt IaS, Luchinina IuA, Surin VL, Luk'ianenko AV, Kravshenko SK, Kremenetskaia AM.AbstractAIM: To analyse manifestations and experience in primary screening diagnosis of acute porphyrias which are rarely encountered and little known by general practitioners.
Terapevticheskiĭ arkhiv.Ter Arkh.2007;79(8):52-6.
AIM: To analyse manifestations and experience in primary screening diagnosis of acute porphyrias which are rarely encountered and little known by general practitioners.MATERIAL AND METHODS: The data on 100 patients with the diagnosis acute porphyria have been analysed. Porphyrin metabolism in differ
PMID 17926472

[Death following administration of 1,250 mg chloroquine in porphyria cutanea tarda].

Drasch G, Eisenmenger W.AbstractThe death of a 23-year-old female patient is reported. She was being treated for porphyria cutanea tarda (p.c.t.) and was mistakenly given a single dose of 1250 mg chloroquine (instead of the intended dose of 125 mg). The course differed from the typical course of chloroquine toxification, which involves cardiac arrhythmias as the main complication (reported in adults only after much higher doses); in spite of intensive care, this patient died 13 days after the ingestion of chloroquine, in a coma caused by irreversible, acute decompensation of the liver. Forensic autopsy and histological and toxicological investigations confirmed the clinical findings. Starting from the chloroquine's pharmacological mechanism of effect in p.c.t., the severe hepatotoxic effect of this drug in the present case is explained. The authors give a serious warning against exceeding the dose of chloroquine now usually recommended for the treatment of the p.c.t., which is 125-250 mg twice weekly. The presence of chronic porphyria hepatica, at least in its clinically manifest form, (= p.c.t.), should be considered a contraindication for chloroquine in prophylaxis and treatment of other illnesses (e.g. malaria and rheumatism).
Zeitschrift für Rechtsmedizin. Journal of legal medicine.Z Rechtsmed.1986;97(4):285-93.
The death of a 23-year-old female patient is reported. She was being treated for porphyria cutanea tarda (p.c.t.) and was mistakenly given a single dose of 1250 mg chloroquine (instead of the intended dose of 125 mg). The course differed from the typical course of chloroquine toxification, which inv
PMID 3577436

Related Links

Hepatic Porphyria | Conditions | UCSF Health

Hepatic Porphyria. Porphyrins are pigments made by the liver and other tissues. They are involved in the formation of many important substances in the body, such as hemoglobin, which carries oxygen in the blood. Many genes are involved in the production of porphyrins. If one of these genes is mutated, hepatic porphyria may occur, resulting in ...

Hepatic Porphyria Treatment | UCSF Health

When acute porphyria progresses despite elimination of triggering factors, hospitalization is necessary. Specific treatment involves administration of intravenous hematin, which compensates for the genetic deficiency. UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to ...

Toxic Effect of Chloroquine on Porphyria Hepatica | JAMA ...

Three patients with porphyria hepatica are reported including I with the mixed type and 2 with porphyria cutanea tarda. The administration of chloroquine, in total doses ranging from 1 to 2.5 gm., resulted in an exacerbation of clinical symptoms by the third or fourth day, manifested by malaise, fever, tachycardia, and impaired liver function.