認容性が低い
症状を悪化させる

WordNet

unsatisfactory; "a poor light for reading"; "poor morale"; "expectations were poor"
characterized by or indicating poverty; "the country had a poor economy"; "they lived in the poor section of town"
having little money or few possessions; "deplored the gap between rich and poor countries"; "the proverbial poor artist living in a garret"
lacking in specific resources, qualities or substances; "a poor land"; "the area was poor in timber and coal"; "food poor in nutritive value"
recognize and respect (rights and beliefs of others); "We must tolerate the religions of others"
have a tolerance for a poison or strong drug or pathogen or environmental condition; "The patient does not tolerate the anti-inflammatory drugs we gave him"

PrepTutorEJDIC

『貧乏な,貧しい』 / 『貧相な』,みすぼらしい / (一定規準よりも)劣る,落ちる / 《名詞の前にのみ用いて》哀れな,不運な,かわいそうな / 《名詞の前にのみ用いて》故人となった,なくなった / 《名詞の前にのみ用いて》《謙そん,またはおどけて》つまらない,取るに足らない / 《the~》《名詞的に》《複数扱い》貧しい人々;かわいそうな人々
…‘に'『寛大な態度をとる』,‘を'黙認する / …‘を'『がまんする』,耐える / 〈薬品・毒物など〉‘に'耐性がある
= poo-poo・（幼児語）うんち・うんちをする

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1. 多発性骨髄腫：使用可能な薬剤などが限られた状態での管理multiple myeloma management in resource poor settings [show details]
… these drugs may not be available in resource-poor settings. The selection of initial treatment regimen for patients with MM in resource-poor settings is discussed here.… The VMP regimen was active and well-tolerated in patients with mild or moderate renal impairment (ie,…
2. 入院中の睡眠不足：要因と介入poor sleep in the hospital contributing factors and interventions [show details]
… of risk factors for poor sleep in the ICU found that pain, shortness of breath, hunger, and nausea were more commonly reported in patients with poor sleep .… , although an effect has not been consistently demonstrated in all studies . Melatonin is well tolerated, and proper timing of the dose may help to regulate circadian rhythms. While dosing is not standardized …
3. 転移性大腸癌を患う高齢患者およびパフォーマンスステータスが不良の患者への治療therapy for metastatic colorectal cancer in older adult patients and those with a poor performance status [show details]
…assess a patient ability to tolerate chemotherapy and to assess short-term prognosis. Regardless of age, patients with a poor PS (eg, ECOG PS >2, KPS or PPS <60) usually tolerate chemotherapy poorly and have …
4. 成人における線維筋痛症の初期治療initial treatment of fibromyalgia in adults [show details]
…measures and treatment with pharmacologic monotherapies at the maximum tolerated dose. Patients should first be evaluated to identify poor medication adherence and its cause and to address associated conditions …
5. 進行非小細胞肺癌への全身化学療法systemic chemotherapy for advanced non small cell lung cancer [show details]
…initial treatment approach. In particular, older adult patients and those with a poor performance status (PS) may not tolerate treatment as well as younger patients with a good PS and may not derive the same …

English Journal

Japanese Journal

Use of low-dose combined therapy with gemcitabine and paclitaxel for advanced urothelial cancer patients with resistance to cisplatin-containing therapy: a retrospective analysis

Miyata Yasuyoshi,Nomata Koichiro,Ohba Kojiro,Matsuo Tomohiro,Sagara Yuji,Kanetake Hiroshi,Sakai Hideki
Cancer Chemotherapy and Pharmacology 70(3), 451-459, 2012-09
… Purpose The prognosis of patients with advanced and recurrent urothelial cancer (UC) is poor. … Conclusions LD-GP therapy is feasible and well tolerated as salvage therapy in patients with advanced UC with resistance to CDDP-containing therapy. …
NAID 120005222466

Salvage treatment with temozolomide in refractory or relapsed primary central nervous system lymphoma and assessment of the MGMT status

Makino Keishi,Nakamura Hideo,Hide Taku-ichiro,Kuratsu Jun-ichi,マキノケイシ,ナカムラヒデオ,ヒデタクイチロウ,クラツジュンイチ,牧野敬史,中村英夫,秀拓一郎,倉津純一
Journal of Neuro-Oncology 106(1), 155-160, 2012-01
… Since the treatment options in patients with progressive or recurrent PCNSL are limited, their prognosis is remains poor. … Temozolomide, a well-tolerated oral alkylating agent that permeates the blood brain barrier, is effective against malignant glioma and recurrent PCNSL. … Although some patients were elderly and had been heavily pre-treated, temozolomide produced a complete response in 29% and was well tolerated without any major toxicity. …
NAID 120005254835

Poorly Differentiated Neuroendocrine Carcinoma of the Pancreas Responsive to Combination Therapy with Gemcitabine and S-1

Yamamoto Mitsuyoshi,Miyagawa Koichiro,Hiura Masaaki,Taguchi Masashi,Kihara Yasuyuki,Abe Shintaro,Shimajiri Shohei,Harada Masaru
Internal Medicine 51(7), 727-732, 2012
… Poorly differentiated neuroendocrine carcinoma is a very rare malignancy, but it is characterized by agressive histological features and a poor clinical prognosis. … This treatment was efficacious and well tolerated, and then this patient obtained objective partial response for 7 months and survived for 13 months after the diagnosis. …
NAID 130002061835