多発性関節痛

関: arthralgia、joint pain

WordNet

pain in a joint or joints

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/09/27 22:13:10」(JST)

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Arthralgia (from Greek arthro-, joint + -algos, pain) literally means joint pain;^[1]^[2] it is a symptom of injury, infection, illnesses (in particular arthritis) or an allergic reaction to medication.^[3]

According to MeSH, the term "arthralgia" should only be used when the condition is non-inflammatory, and the term "arthritis" should be used when the condition is inflammatory.^[4]

Diagnosis and causes[edit]

Diagnosis involves interviewing the patient and performing physical exams. When attempting to establish the cause of the arthralgia, the emphasis is on the interview.^[2] The patient is asked questions intended to narrow the number of potential causes. Given the varied nature of these possible causes, some questions may seem irrelevant. For example, the patient may be asked about dry mouth, light sensitivity, rashes or a history of seizures.^[2]^[5] Answering yes or no to any of these questions limits the number of possible causes and guides the doctor toward the appropriate exams and lab tests.

The causes of arthralgia are varied and range, from a joints perspective, from degenerative and destructive processes such as osteoarthritis and sports injuries to inflammation of tissues surrounding the joints, such as bursitis.^[6] These might be triggered by other things, such as infections or vaccinations.^[7]

Causes of arthralgia[edit]

Cause	Mono- or polyarticular	Speed of onset
Rheumatoid arthritis	Polyarticular ^[8]	Weeks-months^[9]
Systemic lupus erythematosis	Polyarticular^[8]	Months^[10]
Excessive intake of Vitamin A
Viral arthritis	Polyarticular^[8]
Reactive arthritis	Polyarticular^[8]
Rheumatic fever	Polyarticular^[8]
Lyme disease	Polyarticular^[8]
Gonococcal arthritis	Polyarticular^[8]
Hemochromatosis	Polyarticular^[8]
Drug-induced arthritis	Polyarticular^[8]
Osteoarthritis	Monoarticular^[8]
Gout attack	Monoarticular^[8]	Hours^[11]
Pseudogout	Monoarticular^[8]
Physical trauma	Monoarticular^[8]	Immediate
Septic arthritis	Monoarticular^[8]	Hours^[11]
Hemarthrosis	Monoarticular^[8]

Treatment[edit]

Treatment depends on a specific underlying cause. The underlying cause will be treated first and foremost. The treatments may include using joint supplements, joint replacement surgery, for severely damaged joints, immunosuppressants for immune system dysfunction, antibiotics when an infection is the cause, and discontinuing medication when an allergic reaction is the cause. Conservative chiropractic care has also shown to be beneficial in the relief of symptoms.^{[citation needed]} When treating the primary cause, pain management may still play a role in treatment. The extent of its role varies depending on the specific cause of the arthralgia. Pain management may include stretching exercises, over the counter pain medications, prescription pain medication, or other treatments deemed appropriate for the symptoms.

References[edit]

^ "Arthralgia Definition". MedicineNet.com. Archived from the original on 11 October 2007. Retrieved 2007-09-20.
^ ^a ^b ^c Joe G. Hardin. "Arthralgia". Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.
^ James R Philp. "Allergic Drug Reactions - Systemic Allergic Drug Reactions". Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.
^ "MeSH". Retrieved 2007-12-23.
^ "Table 159mptomatic Extraarticular Features of the Connective Tissue Diseases and the Spondyloarthropathies". Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.
^ Joe G. Hardin. "Table 161.1. Some Common Regional Rheumatic Syndromes". Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.
^ Loris McVittie, Ph.D. "Information from CDC and FDA on the Safety of Gardasil Vaccine". supplement to your biologics license application (BLA) for Human Papillomavirus Quadrivalent (Types 6, 11, 16 and 18) Vaccine, Recombinant (GARDASIL), to include arthralgia, myalgia, asthenia, fatigue, and malaise in the Adverse Reactions section of the package insert. Retrieved 2008-07-21. ^{[dead link]}
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o Table 6-8 in: Elizabeth D Agabegi; Agabegi, Steven S. (2008). Step-Up to Medicine (Step-Up Series). Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-7153-6.
^ Diagnosis lag time of median 4 weeks, and median diagnosis lag time of 18 weeks, taken from: Chan, K. W.; Felson, D. T.; Yood, R. A.; Walker, A. M. (1994). "The lag time between onset of symptoms and diagnosis of rheumatoid arthritis". Arthritis and rheumatism 37 (6): 814–820. PMID 8003053. edit
^ Doria, A.; Zen, M.; Canova, M.; Bettio, S.; Bassi, N.; Nalotto, L.; Rampudda, M.; Ghirardello, A.; Iaccarino, L. (2010). "SLE diagnosis and treatment: When early is early". Autoimmunity Reviews 10 (1): 55–60. doi:10.1016/j.autrev.2010.08.014. PMID 20813207. edit
^ ^a ^b Page 740 (upper right of page) in: Schaider, Jeffrey; Wolfson, Allan B.; Gregory W Hendey; Louis Ling; Carlo L Rosen (2009). Harwood-Nuss' Clinical Practice of Emergency Medicine (Clinical Practice of Emergency Medicine (Harwood-Nuss)). Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-8943-5.

UpToDate Contents

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1. 関節リウマチの診断および鑑別診断 diagnosis and differential diagnosis of rheumatoid arthritis
2. 播種性淋菌感染 disseminated gonococcal infection
3. 多関節型若年性特発性関節炎：臨床症状、診断および合併症 polyarticular juvenile idiopathic arthritis clinical manifestations diagnosis and complications
4. 淋病の皮膚症状 cutaneous manifestations of gonorrhea
5. チクングンヤ熱 chikungunya fever

English Journal

Diagnostic criteria for temporomandibular disorders: self-instruction or formal training and calibration?

Vilanova LS1, Garcia RC, List T, Alstergren P.
The journal of headache and pain.J Headache Pain.2015 Dec;16:505. doi: 10.1186/s10194-015-0505-9. Epub 2015 Mar 25.
BACKGROUND: To investigate the difference in diagnostic reliability between self-instructed examiners and examiners taught in a Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) course and if the reliability of self-instructed examiners improves after the course.METHODS: Six examiners wer
PMID 25916330

First report of autochthonous transmission of Zika virus in Brazil.

Zanluca C1, Melo VC2, Mosimann AL1, Santos GI2, Santos CN1, Luz K3.
Memorias do Instituto Oswaldo Cruz.Mem Inst Oswaldo Cruz.2015 09/06;110(4):569-572. Epub 2015 Jun 9.
In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infe
PMID 26061233

Use of complementary and alternative medicines for menopausal symptoms in Australian women aged 40-65 years.

Gartoulla P1, Davis SR, Worsley R, Bell RJ, Gartoulla P, Davis SR, Worsley R, Bell RJ.
The Medical journal of Australia.Med J Aust.2015 Aug 3;203(3):146.
OBJECTIVE: To document the prevalence of, and factors associated with, the use of complementary and alternative medicines (CAMs) for vasomotor symptoms (VMS) and other symptoms of menopause in Australian women aged 40-65 years.DESIGN, SETTING AND PARTICIPANTS: Cross-sectional questionnaire-based stu
PMID 26224187

Japanese Journal

今月の症例発熱,多関節痛を伴った急性サルコイドーシスの1例

日本内科学会雑誌 105(3), 540-546, 2016-03-10
NAID 40020765846

タクロリムスが著効した成人スティル病の１例

臨床リウマチ 27(3), 198-204, 2015
NAID 130005110303

Chikungunya Virus Infection Presenting with Persistent Arthralgia without Fever

Journal of General and Family Medicine 16(3), 204-207, 2015
NAID 130005107508

「joint pain」

Arthralgia
	Classification and external resources
ICD-10	M25.5
ICD-9	719.4
DiseasesDB	15237
MedlinePlus	003261
MeSH	D018771

　　[★]

関節痛

関: arthralgia、polyarthralgia

「多発性関節痛」

　　[★]

英: polyarthralgia
関: 関節痛

[medterms_arthralgia-1] "Arthralgia Definition". MedicineNet.com. Archived from the original on 11 October 2007. Retrieved 2007-09-20.

[jgh_arthralgia-2] Joe G. Hardin. "Arthralgia". Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.

[drugReaction-3] James R Philp. "Allergic Drug Reactions - Systemic Allergic Drug Reactions". Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.

[title-4] "MeSH". Retrieved 2007-12-23.

[spondyl_table1-5] "Table 159mptomatic Extraarticular Features of the Connective Tissue Diseases and the Spondyloarthropathies". Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.

[nihbook_2-6] Joe G. Hardin. "Table 161.1. Some Common Regional Rheumatic Syndromes". Clinical Methods - The History, Physical, and Laboratory Examinations. Retrieved 2007-09-20.

[Gardasil-7] Loris McVittie, Ph.D. "Information from CDC and FDA on the Safety of Gardasil Vaccine". supplement to your biologics license application (BLA) for Human Papillomavirus Quadrivalent (Types 6, 11, 16 and 18) Vaccine, Recombinant (GARDASIL), to include arthralgia, myalgia, asthenia, fatigue, and malaise in the Adverse Reactions section of the package insert. Retrieved 2008-07-21. ^{[dead link]}

[agabegi2nd6-8-8] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o Table 6-8 in: Elizabeth D Agabegi; Agabegi, Steven S. (2008). Step-Up to Medicine (Step-Up Series). Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-7153-6.

[Chan1994-9] Diagnosis lag time of median 4 weeks, and median diagnosis lag time of 18 weeks, taken from: Chan, K. W.; Felson, D. T.; Yood, R. A.; Walker, A. M. (1994). "The lag time between onset of symptoms and diagnosis of rheumatoid arthritis". Arthritis and rheumatism 37 (6): 814–820. PMID 8003053. edit

[10] Doria, A.; Zen, M.; Canova, M.; Bettio, S.; Bassi, N.; Nalotto, L.; Rampudda, M.; Ghirardello, A.; Iaccarino, L. (2010). "SLE diagnosis and treatment: When early is early". Autoimmunity Reviews 10 (1): 55–60. doi:10.1016/j.autrev.2010.08.014. PMID 20813207. edit

[Harwood-Nuss2009-11] Page 740 (upper right of page) in: Schaider, Jeffrey; Wolfson, Allan B.; Gregory W Hendey; Louis Ling; Carlo L Rosen (2009). Harwood-Nuss' Clinical Practice of Emergency Medicine (Clinical Practice of Emergency Medicine (Harwood-Nuss)). Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-8943-5.

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polyarthralgia