English Journal

Blastomatoid pulmonary carcinosarcoma: report of a case with a review of the literature.

Schaefer IM, Sahlmann CO, Overbeck T, Schweyer S, Menke J.AbstractABSTRACT: BACKGROUND: Pulmonary carcinosarcoma is a biphasic tumour with an unfavourable prognosis. The differential diagnosis includes pulmonary blastoma and is often challenging.
BMC cancer.BMC Cancer.2012 Sep 25;12(1):424. [Epub ahead of print]
ABSTRACT: BACKGROUND: Pulmonary carcinosarcoma is a biphasic tumour with an unfavourable prognosis. The differential diagnosis includes pulmonary blastoma and is often challenging.CASE PRESENTATION: We here describe a case of blastomatoid pulmonary carcinosarcoma in a 58-year-old patient, who underw
PMID 23006472

DICER1 mutations in embryonal rhabdomyosarcomas from children with and without familial PPB-tumor predisposition syndrome.

Doros L, Yang J, Dehner L, Rossi CT, Skiver K, Jarzembowski JA, Messinger Y, Schultz KA, Williams G, André N, Hill DA.SourceDepartment of Pathology, Children's National Medical Center, Washington, District of Columbia 20010, USA.
Pediatric blood & cancer.Pediatr Blood Cancer.2012 Sep;59(3):558-60. doi: 10.1002/pbc.24020. Epub 2011 Dec 16.
Embryonal rhabdomyosarcoma (ERMS) is the most common childhood sarcoma and is a component of the familial pleuropulmonary blastoma (PPB)-predisposition syndrome. Using the PPB model, we hypothesized that DICER1 mutations would be found in familial and sporadic forms of ERMS. Blood samples from four
PMID 22180160