plasmacytosis

形質細胞増加症

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/02/06 11:16:04」(JST)

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This article is about the disease found in humans. For the disease that affects mustelids, see Aleutian disease.

Plasmacytosis
Classification and external resources
ICD-9	288.64

Plasmacytosis is a condition in which there is an unusually large proportion of plasma cells in tissues, exudates, or blood. Plasmacytosis may be divided into two types—cutaneous and systemic—both of which have identical skin findings.

Patients with plasmacytosis have been predominantly found to have lung infections (pneumonia, tuberculosis, abscess) whereas multiple myeloma is rarely found.

See also

• Cutaneous B-cell lymphoma
• Multiple myeloma
• Plasmacytoma
• Skin lesion

References

UpToDate Contents

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• 1. 多発性骨髄腫の臨床的特徴、検査所見、および診断 clinical features laboratory manifestations and diagnosis of multiple myeloma
• 2. 形質細胞白血病 plasma cell leukemia
• 3. POEMS症候群 poems syndrome
• 4. 骨の孤立性形質細胞腫の診断およびマネージメント diagnosis and management of solitary plasmacytoma of bone
• 5. 多中心性キャッスルマン病 multicentric castlemans disease

English Journal

• Multiple myeloma: 2016 update on diagnosis, risk-stratification, and management.

• Rajkumar SV1.
• American journal of hematology.Am J Hematol.2016 Jul;91(7):719-34. doi: 10.1002/ajh.24402.
• Multiple myeloma accounts for approximately 10% of hematologic malignancies.The diagnosis requires ≥10% clonal bone marrow plasma cells or a biopsy proven plasmacytoma plus evidence of one or more multiple myeloma defining events (MDE): CRAB (hypercalcemia, renal failure, anemia, or lytic bone les
• PMID 27291302

• Induction Therapy Pre-Autologous Stem Cell Transplantation in Immunoglobulin Light Chain Amyloidosis: A Retrospective Evaluation.

• Hwa YL1, Kumar SK1, Gertz MA1, Lacy MQ1, Buadi FK1, Kourelis TV1, Gonsalves WI1, Rajkumar SV1, Go RS1, Leung N1, Kapoor P1, Dingli D1, Kyle RA1, Russell S1, Lust JA1, Hayman SR1, Lin Y1, Zeldenrust S1, Dispenzieri A1.
• American journal of hematology.Am J Hematol.2016 Jun 24. doi: 10.1002/ajh.24453. [Epub ahead of print]
• There is no consensus on whether patients with immunoglobulin light chain amyloidosis (AL) should receive induction therapy prior to an autologous stem cell transplant (ASCT). This study investigated the relationships between baseline bone marrow plasmacytosis (BMPC), cardiac staging, and pre-transp
• PMID 27341539

• Monoclonal gammopathy-associated pure red cell aplasia.

• Korde N1,2, Zhang Y2, Loeliger K3, Poon A3, Simakova O4, Zingone A2, Costello R2, Childs R3, Noel P5, Silver S6, Kwok M7, Mo C7, Young N3, Landgren O1,2, Sloand E3, Maric I5.
• British journal of haematology.Br J Haematol.2016 Jun;173(6):876-83. doi: 10.1111/bjh.14012. Epub 2016 Mar 21.
• Pure red cell aplasia (PRCA) is a rare disorder characterized by inhibition of erythroid precursors in the bone marrow and normochromic, normocytic anaemia with reticulocytopenia. Among 51 PRCA patients, we identified 12 (24%) patients having monoclonal gammopathy, monoclonal gammopathy of undetermi
• PMID 26999424

Japanese Journal

• 形質細胞性白血病を疑わせるほど末梢血および骨髄に著明な多クローン性形質細胞増生を伴った Angioimmunoblastic T-cell lymphoma

• 三橋 健次郎,志関 雅幸,石山 みどり,近藤 年昭,風間 啓至,安並 毅,岡村 隆光,吉永 健太郎,森 直樹,寺村 正尚,増田 昭博,泉二 登志子
• 臨床血液 52(7), 563-569, 2011-07-30
• NAID 10029426010

• 症例 トシリズマブが奏効した全身性形質細胞増多症の1例

• 林 周次郎,[ハタ]持 淳,濱崎 洋一郎 [他]
• 皮膚科の臨床 53(6), 899-902, 2011-06
• NAID 40018873473

Related Pictures

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★リンクテーブル★

リンク元	「多クローン性高γグロブリン血症」

「多クローン性高γグロブリン血症」

　　[★]

英

polyclonal hypergammaglobulinemia

同

多クローン性高免疫グロブリン血症 polyclonal hyperimmunoglobulinemia

関

高γグロブリン血症

[show details]

多クローン性高γ-グロブリン血症 : 約 1,410 件
多クローン性高γグロブリン血症 : 約 1,410 件
多クローン性高ガンマグロブリン血症 : 71 件
多クローン性高免疫グロブリン血症 : 23 件

概念

• 血清蛋白電気泳動のガンマグロブリン分画で幅広いピーク
• 多クローン性の抗体産生細胞の増加による 。骨髄では多クローン性の形質細胞増多 plasmacytosisがみられ、多クローン性の高ガンマグロブリン血症をきたす(WCH.2619)。
• 慢性炎症疾患(自己免疫疾患(SLE)、肝疾患(肝硬変、慢性肝炎)、慢性炎症(慢性感染症、悪性腫瘍))