pituitary disease

WordNet

1. an impairment of health or a condition of abnormal functioning
2. of or relating to the pituitary gland; "pituitary hormone"
3. the master gland of the endocrine system; located at the base of the brain (同)pituitary_gland, pituitary body, hypophysis
4. caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological

PrepTutorEJDIC

1. (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
2. 女性の話術芸人 =diseur
3. 脳下垂体の(から得られた) / =pituitary gland
4. 病気にかかった / 病的な,不健全な(morbid)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/25 01:03:53」(JST)

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Pituitary disease
Classification and external resources
Pituitary
MeSH	D010900

A Pituitary disease is a disorder primarily affecting the pituitary gland.

The main disorders involving the pituitary gland are:

Condition	Direction	Hormone
Acromegaly	overproduction	growth hormone
Cushing's disease	overproduction	Adrenocorticotropic hormone
Growth hormone deficiency	underproduction	growth hormone
Syndrome of inappropriate antidiuretic hormone	overproduction	vasopressin
Diabetes insipidus (can also be nephrogenic)	underproduction	vasopressin
Sheehan syndrome	underproduction	any pituitary hormone
Pickardt-Fahlbusch-Syndrome	underproduction	any pituitary hormone, except prolactin, which is increased
Hyperpituitarism (most commonly pituitary adenoma)	overproduction	any pituitary hormone
Hypopituitarism	underproduction	any pituitary hormone

Over- or underproduction of a pituitary hormone will effect the respective end-organ. For example insufficient production (hyposecretion) of thyroid stimulating hormone (TSH) in the pituitary gland will cause hypothyroidism, while overproduction (hypersecretion) of TSH will cause hyperthyroidism. Thyroidisms caused by the pituitary gland are less common though, accounting for less than 10% of all hypothyroidism cases and much less than 1% of hyperthyroidism cases.

See also

• Hypophysitis, inflammation of the pituitary gland.
• Autoimmune hypophysitis (or lymphocytic hypophysitis), inflammation of the pituitary gland due to autoimmunity.
• Pituitary tumour, a tumor of the pituitary gland.
• Pituitary adenoma, a noncancerous tumor of the pituitary gland.
• Pituicytoma, a rare brain tumor.
• Pituitary apoplexy, bleeding into or impaired blood supply of the pituitary gland.

References

UpToDate Contents

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• 1. 視床下部下垂体軸 hypothalamic pituitary axis
• 2. 鞍部腫瘤の原因、症状、および評価 causes presentation and evaluation of sellar masses
• 3. 下垂体機能低下症の診断 diagnosis of hypopituitarism
• 4. 偶然発見された鞍部腫瘤（下垂体偶発） incidentally discovered sellar masses pituitary incidentalomas
• 5. 下垂体機能低下症の原因 causes of hypopituitarism

English Journal

• Dynamics of adrenal glucocorticoid steroidogenesis in health and disease.

• Spiga F1, Lightman SL2.
• Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Jun 15;408:227-234. doi: 10.1016/j.mce.2015.02.005. Epub 2015 Feb 7.
• The activity of the hypothalamic-pituitary-adrenal (HPA) axis is characterized by an ultradian (pulsatile) pattern of hormone secretion. Pulsatility of glucocorticoids has been found critical for optimal transcriptional, neuroendocrine and behavioral responses. This review will focus on the mechanis
• PMID 25662280

• Current approaches to the pharmacological management of Cushing's disease.

• Molitch ME1.
• Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Jun 15;408:185-189. doi: 10.1016/j.mce.2014.09.021. Epub 2014 Oct 29.
• If treatment of Cushing's disease (CD) by surgery is not successful, medical therapy is often required. Long-term use of metyrapone is limited by hirsutism and hypertension and escape because of increased ACTH levels. Although ketoconazole can normalize cortisol levels in 50%, liver toxicity limits
• PMID 25450859

• Paracrine control of steroidogenesis by serotonin in adrenocortical neoplasms.

• Lefebvre H1, Duparc C2, Prévost G3, Zennaro MC4, Bertherat J5, Louiset E2.
• Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Jun 15;408:198-204. doi: 10.1016/j.mce.2014.11.013. Epub 2014 Nov 26.
• Serotonin (5-hydroxytryptamine; 5-HT) is able to activate the hypothalamo-pituitary-adrenal axis via multiple actions at different levels. In the human adrenal gland, 5-HT, released by subcapsular mast cells, stimulates corticosteroid production through a paracrine mode of communication which involv
• PMID 25433205

Japanese Journal

• 臨床研究・症例報告 加療中にペルテス病を合併した複合型下垂体ホルモン欠損症患者への成長ホルモンの長期使用経験

• 後藤 正博,長谷川 行洋,下村 哲史
• 小児科臨床 67(2), 257-261, 2014-02
• NAID 40019945784

• Occurrence of IgG4-related Hypophysitis Lacking IgG4-bearing Plasma Cell Infiltration during Steroid Therapy

• Ohkubo Yohsuke,Sekido Takashi,Takeshige Keiko,Ishi Hiroaki,Takei Masahiro,Nishio Shin-ichi,Yamazaki Masanori,Komatsu Mitsuhisa,Kawa Shigeyuki,Suzuki Satoru
• Internal Medicine 53(7), 753-757, 2014
• … Eight years after an episode of multiple IgG4-related disease, a pituitary mass with panhypopituitarism and a visual disturbance developed in a 70-year-old man under low-dose steroid therapy. … A pituitary biopsy revealed findings of lymphocytic hypophysitis with the absence of IgG4-positive plasma cell infiltration. …
• NAID 130003392728

• Therapeutic Potential of Vasopressin-Receptor Antagonists in Heart Failure

• Izumi Yasukatsu,Miura Katsuyuki,Iwao Hiroshi
• Journal of Pharmacological Sciences 124(1), 1-6, 2014
• … Arginine vasopressin (AVP) is a 9-amino acid peptide that is secreted from the posterior pituitary in response to high plasma osmolality and hypotension. … AVP has important roles in circulatory and water homoeostasis, which are mediated by oxytocin receptors and by AVP receptor subtypes: V1a (mainly vascular), V1b (pituitary), and V2 (renal). … A selective V1a-receptor antagonist, relcovaptan, has shown initial positive results in the treatment of Raynaud's disease, dysmenorrhea, and tocolysis. …
• NAID 130003382634

Related Links

• Pituitary disease - Wikipedia, the free encyclopedia

A Pituitary disease is a disorder primarily affecting the pituitary gland. The main disorders involving the pituitary gland are: Condition, Direction, Hormone. Acromegaly, overproduction, growth hormone · Cushing's disease, overproduction ...

Related Pictures

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★リンクテーブル★

リンク元	「下垂体疾患」
拡張検索	「anterior pituitary disease」「hypothalamo-pituitary disease」
関連記事	「disease」「pituitary」

「下垂体疾患」

　　[★]

英

pituitary disease、pituitary disorder

関

下垂体障害、下垂体前葉疾患

「anterior pituitary disease」

　　[★]

下垂体前葉疾患

関

pituitary disease、pituitary disorder

「hypothalamo-pituitary disease」

　　[★]

• 視床下部下垂体疾患

「disease」

　　[★]

• n.

疾患：illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)

特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)

• something that is very wrong with people's attitudes, way of life or with society.

関

ail、ailment、disease entity、disorder、ill、illness、malady、sick、sickness

• 注意

disease ≠ illness ≠ disorder

　 　 　

「pituitary」

　　[★]

• adj.

• 下垂体の

関

hypophyses、hypophysis、pituitary gland