WordNet

inflammation of the skin; skin becomes itchy and may develop blisters

PrepTutorEJDIC

皮膚炎

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/21 10:57:14」(JST)

wiki en

Phytophotodermatitis, also known as "lime disease" (not to be confused with Lyme disease),^[1] "Berloque dermatitis",^[2] or "Margarita photodermatitis"^[3]^[4] is a chemical reaction which makes skin hypersensitive to ultraviolet light. It is frequently mistaken for hereditary conditions such as atopic dermatitis or chemical burns, but it is caused by contact with the photosensitizing compounds found naturally in some plants and vegetables like parsnips, citrus fruits and more. Symptoms include burning, itching, stinging and large blisters that slowly accumulate over time.^[5]

Symptoms

The symptoms are equivalent to photodermatitis, but vary in severity. The skin condition is a cutaneous phototoxic inflammatory eruption resulting from contact with light-sensitizing botanical substances—particularly from the plant families Umbelliferae, Rutaceae, Moraceae, and Leguminosae—and ultraviolet light, typically from sun exposure. Phytophotodermatitis usually results in hyperpigmentation of the skin that often appears like a bruise. This may be accompanied by blisters or burning. The reaction typically begins within 24 hours of exposure and peaks at 48–72 hours after the exposure.^[6]

Effect of the common rue on skin

A severe case of phytophotodermatitis

Phytophotodermatitis can affect people of any age. Because of the bruise-like appearance that is usually in the shape of handprints or fingerprints, it can be mistaken in children for child abuse.^[7]

Common causes

- Parsnip, parsley, celery, common hogweed, giant hogweed^[8]^[9]^[10]
- Carrot^[11] and wild carrot^[6]
- Notobubon galbanum (previously known by the synonym Peucedanum galbanum),^[12] a South African plant also known as "blister bush", "hog's fennel", or locally in Afrikaans as bergseldery (i.e. "mountain celery")^[13]
- Lemon, lime, bergamot orange^[1]^[8]^[14]
- Common rue (Ruta graveolens) and other plants in the genus Ruta^[15]^[16]^[17]^[18]
Sclerotinia sclerotiorum, which can infect celery^[19]
Common fig, its latex contains various furocoumarin isomers such as 8-methoxypsoralen, which induce allergic photodermatitis^[8]^[20]^[21]

Treatment

Phytophotodermatitis can be prevented by staying indoors after handling the above substances. However, the primary triggering mechanism is UV-A radiation (320-380 nm) which windows are not guaranteed to filter out.

Many different topical and oral medications can be used to treat the inflammatory reaction of phytophotodermatitis. A dermatologist may also prescribe a bleaching cream to help treat the hyperpigmentation and return the skin pigmentation back to normal. If they do not receive treatment, the affected sites may develop permanent hyperpigmentation or hypopigmentation.^[6]

References

^ ^a ^b Weber, Ian C; Davis, Charles P; Greeson, David M (1999). "Phytophotodermatitis: The other 'lime' disease". The Journal of Emergency Medicine 17 (2): 235–7. doi:10.1016/S0736-4679(98)00159-0. PMID 10195477.
^ James, William Daniel; Berger, Timothy G.; Elston, Dirk M., eds. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. p. 32. ISBN 978-0-7216-2921-6.
^ Riahi, Ryan R.; Cohen, Philip R.; Robinson, Floyd W.; Gray, James M. (June 2009). "What Caused The Rash On This Man's Wrist And Hand?". The Dermatologist 11 (6).
^ Abramowitz, Alan I.; Resnik, Kenneth S.; Cohen, Kenneth R. (1993). "Margarita Photodermatitis". New England Journal of Medicine 328 (12): 891. doi:10.1056/NEJM199303253281220. PMID 8441448.
^ Solis, R. R.; Dotson, DA; Trizna, Z (2000). "Phytophotodermatitis: A Sometimes Difficult Diagnosis". Archives of Family Medicine 9 (10): 1195–6. doi:10.1001/archfami.9.10.1195. PMID 11115230.
^ ^a ^b ^c Phytophotodermatitis at eMedicine
^ Barradell, R.; Addo, A.; McDonagh, A. J. G.; Cork, M. J.; Wales, J. K. H. (1993). "Phytophotodermatitis mimicking child abuse". European Journal of Pediatrics 152 (4): 291–2. doi:10.1007/BF01956735. PMID 8482273.
^ ^a ^b ^c Photocontact dermatitis. DermNet NZ^{[unreliable medical source?]}
^ Lutchman, L; Inyang, V; Hodgkinson, D (1999). "Phytophotodermatitis associated with parsnip picking". Emergency Medicine Journal 16 (6): 453–4. doi:10.1136/emj.16.6.453. PMC: 1343418. PMID 10572825.
^ Giant Hogweed phytophotodermatitis GPnotebook login required^{[unreliable medical source?]}
^ Klauder, Joseph V.; Klauder, JV (1956). "Sensitization Dermatitis to Carrots: Report of Cross-Sensitization Phenomenon and Remarks on Phytophotodermatitis". Archives of Dermatology 74 (2): 149–58. doi:10.1001/archderm.1956.01550080035006. PMID 13353987.
^ The Plant List (2013). Version 1.1. Published on the Internet; http://www.theplantlist.org/ (accessed 19th December 2015)
^ Manning, John (2008). Field Guide to Fynbos. Cape Town: Struik Publishers. ISBN 9781770072657.
^ Leung; Fong, Justine H. S. (April 1, 2003). "Alexander K. C".
^ Arias-Santiago, S. A.; Fernández-Pugnaire, M. A.; Almazán-Fernández, F. M.; Serrano-Falcón, C.; Serrano-Ortega, S. (2009). "Phytophotodermatitis due to Ruta graveolens prescribed for fibromyalgia". Rheumatology 48 (11): 1401. doi:10.1093/rheumatology/kep234. PMID 19671699.
^ Furniss, Dominic; Adams, Titus (2007). "Herb of Grace: An Unusual Cause of Phytophotodermatitis Mimicking Burn Injury". Journal of Burn Care & Research 28 (5): 767–9. doi:10.1097/BCR.0B013E318148CB82. PMID 17667834.
^ Eickhorst, Kimberly; Deleo, Vincent; Csaposs, Joan (2007). "Rue the Herb: Ruta graveolens–Associated Phytophototoxicity". Dermatitis 18 (1): 52–5. doi:10.2310/6620.2007.06033. PMID 17303046.
^ Wessner, D.; Hofmann, H.; Ring, J. (1999). "Phytophotodermatitis due to Ruta graveolens applied as protection against evil spells". Contact Dermatitis 41 (4): 232. doi:10.1111/j.1600-0536.1999.tb06145.x. PMID 10515113.
^ Centers for Disease Control (CDC) (January 11, 1985). "Phytophotodermatitis among Grocery Workers - Ohio". Morbidity and Mortality Weekly Report 34 (1): 11–3. PMID 3155560.
^ Bonamonte D, Foti C, Lionetti N, Rigano L, Angelini G (June 2010). "Photoallergic contact dermatitis to 8-methoxypsoralen in Ficus carica". Contact Dermatitis 62 (6): 343–8. doi:10.1111/j.1600-0536.2010.01713.x. PMID 20557340.
^ allergy to latex, including fig latex http://www.medic8.com/healthguide/allergies/latex-allergies/symptoms-latex-allergy.html

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 皮膚炎の概要 overview of dermatitis
2. 放射線皮膚炎 radiation dermatitis
3. 成人における刺激性接触皮膚炎 irritant contact dermatitis in adults
4. うっ滞性皮膚炎 stasis dermatitis
5. おむつ皮膚炎 diaper dermatitis

English Journal

Photoallergic contact dermatitis due to treatment of pulmonary fibrosis with pirfenidone.

Reinholz M1, Eder I1, Przybilla B1, Schauber J1, Wollenberg A1, Wulffen W2, Goldscheider I1, Varga R1, Ruzicka T1, Schaumann A3, Ruëff F1.
Journal of the European Academy of Dermatology and Venereology : JEADV.J Eur Acad Dermatol Venereol.2016 Feb;30(2):370-1. doi: 10.1111/jdv.12794. Epub 2014 Oct 20.
PMID 25327710

Photopatch testing in Bogota (Colombia): 2011-2013.

Valbuena Mesa MC1, Hoyos Jiménez EV1.
Contact dermatitis.Contact Dermatitis.2016 Jan;74(1):11-7. doi: 10.1111/cod.12421. Epub 2015 Jun 18.
BACKGROUND: Photopatch tests are used to diagnose photoallergic contact dermatitis and identify the causal agents. The frequencies of positive results and associated allergens vary by country; therefore, it is necessary to know the information specific to each country.OBJECTIVE: To establish the fre
PMID 26086895

Japanese Journal

症例報告スプロフェンによる光接触皮膚炎の1例 : ケトプロフェンとの光交差反応性

臨床皮膚科 = Japanese journal of clinical dermatology 70(4), 284-288, 2016-04
NAID 40020784470

湿布剤中のアボベンゾンにより感作されたサンスクリーンによる光接触皮膚炎

日本皮膚アレルギー・接触皮膚炎学会雑誌 10(2), 125-129, 2016
NAID 130005153733

「光接触皮膚炎」

Phytophotodermatitis
	Phytophotodermatitis caused by lime
Classification and external resources
Specialty	dermatology
ICD-10	L56.2
DiseasesDB	31395
	[edit on Wikidata]

　　[★]

英: photocontact dermatitis
関: 光アレルギー、光アレルギー性皮膚炎、光アレルギー性接触皮膚炎

「photoallergic contact dermatitis」

　　[★]

光アレルギー性接触皮膚炎

関: photoallergic dermatitis、photoallergy、photocontact dermatitis

[Weber_et_al_1999-1] Weber, Ian C; Davis, Charles P; Greeson, David M (1999). "Phytophotodermatitis: The other 'lime' disease". The Journal of Emergency Medicine 17 (2): 235–7. doi:10.1016/S0736-4679(98)00159-0. PMID 10195477.

[Andrews-2] James, William Daniel; Berger, Timothy G.; Elston, Dirk M., eds. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. p. 32. ISBN 978-0-7216-2921-6.

[3] Riahi, Ryan R.; Cohen, Philip R.; Robinson, Floyd W.; Gray, James M. (June 2009). "What Caused The Rash On This Man's Wrist And Hand?". The Dermatologist 11 (6).

[4] Abramowitz, Alan I.; Resnik, Kenneth S.; Cohen, Kenneth R. (1993). "Margarita Photodermatitis". New England Journal of Medicine 328 (12): 891. doi:10.1056/NEJM199303253281220. PMID 8441448.

[5] Solis, R. R.; Dotson, DA; Trizna, Z (2000). "Phytophotodermatitis: A Sometimes Difficult Diagnosis". Archives of Family Medicine 9 (10): 1195–6. doi:10.1001/archfami.9.10.1195. PMID 11115230.

[EMedicine1119566-6] Phytophotodermatitis at eMedicine

[7] Barradell, R.; Addo, A.; McDonagh, A. J. G.; Cork, M. J.; Wales, J. K. H. (1993). "Phytophotodermatitis mimicking child abuse". European Journal of Pediatrics 152 (4): 291–2. doi:10.1007/BF01956735. PMID 8482273.

[dermnetnz-8] Photocontact dermatitis. DermNet NZ^{[unreliable medical source?]}

[9] Lutchman, L; Inyang, V; Hodgkinson, D (1999). "Phytophotodermatitis associated with parsnip picking". Emergency Medicine Journal 16 (6): 453–4. doi:10.1136/emj.16.6.453. PMC: 1343418. PMID 10572825.

[10] Giant Hogweed phytophotodermatitis GPnotebook login required^{[unreliable medical source?]}

[11] Klauder, Joseph V.; Klauder, JV (1956). "Sensitization Dermatitis to Carrots: Report of Cross-Sensitization Phenomenon and Remarks on Phytophotodermatitis". Archives of Dermatology 74 (2): 149–58. doi:10.1001/archderm.1956.01550080035006. PMID 13353987.

[12] The Plant List (2013). Version 1.1. Published on the Internet; http://www.theplantlist.org/ (accessed 19th December 2015)

[JManningFB-13] Manning, John (2008). Field Guide to Fynbos. Cape Town: Struik Publishers. ISBN 9781770072657.

[14] Leung; Fong, Justine H. S. (April 1, 2003). "Alexander K. C".

[15] Arias-Santiago, S. A.; Fernández-Pugnaire, M. A.; Almazán-Fernández, F. M.; Serrano-Falcón, C.; Serrano-Ortega, S. (2009). "Phytophotodermatitis due to Ruta graveolens prescribed for fibromyalgia". Rheumatology 48 (11): 1401. doi:10.1093/rheumatology/kep234. PMID 19671699.

[16] Furniss, Dominic; Adams, Titus (2007). "Herb of Grace: An Unusual Cause of Phytophotodermatitis Mimicking Burn Injury". Journal of Burn Care & Research 28 (5): 767–9. doi:10.1097/BCR.0B013E318148CB82. PMID 17667834.

[17] Eickhorst, Kimberly; Deleo, Vincent; Csaposs, Joan (2007). "Rue the Herb: Ruta graveolens–Associated Phytophototoxicity". Dermatitis 18 (1): 52–5. doi:10.2310/6620.2007.06033. PMID 17303046.

[18] Wessner, D.; Hofmann, H.; Ring, J. (1999). "Phytophotodermatitis due to Ruta graveolens applied as protection against evil spells". Contact Dermatitis 41 (4): 232. doi:10.1111/j.1600-0536.1999.tb06145.x. PMID 10515113.

[19] Centers for Disease Control (CDC) (January 11, 1985). "Phytophotodermatitis among Grocery Workers - Ohio". Morbidity and Mortality Weekly Report 34 (1): 11–3. PMID 3155560.

[20] Bonamonte D, Foti C, Lionetti N, Rigano L, Angelini G (June 2010). "Photoallergic contact dermatitis to 8-methoxypsoralen in Ficus carica". Contact Dermatitis 62 (6): 343–8. doi:10.1111/j.1600-0536.2010.01713.x. PMID 20557340.

[21] rgy to latex, including fig latex http://www.medic8.com/healthguide/allergies/latex-allergies/symptoms-latex-allergy.html

匿名

検索

案内

案内

photocontact dermatitis