WordNet

arrange (open windows) on a computer desktop so that they overlap each other, with the title bars visible
a small waterfall or series of small waterfalls
a succession of stages or operations or processes or units; "progressing in severity as though a cascade of genetic damage was occurring"; "separation of isotopes by a cascade of processes"
rush down in big quantities, like a cascade (同)cascade down

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/20 19:41:16」(JST)

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1. T細胞受容体シグナル伝達 t cell receptor signaling
2. インスリン受容体の構造および機能 structure and function of the insulin receptor
3. 成長ホルモンの生理学 physiology of growth hormone
4. HIVヌクレオシド系逆転写酵素阻害剤のミトコンドリア毒性 mitochondrial toxicity of hiv nucleoside reverse transcriptase inhibitors
5. アポトーシスと自己免疫疾患 apoptosis and autoimmune disease

Sphingosylphosphorylcholine regulates the Hippo signaling pathway in a dual manner.

Kemppainen K1, Wentus N1, Lassila T1, Laiho A2, Törnquist K3.
Cellular signalling.Cell Signal.2016 Dec;28(12):1894-1903. doi: 10.1016/j.cellsig.2016.09.004. Epub 2016 Sep 12.
Sphingosylphosphorylcholine (SPC) is a bioactive sphingolipid which regulates many cancer-related processes, including cellular proliferation. The Hippo signaling pathway consists of a cascade of tumor suppressive kinases Mst1/2 and Lats1/2 and their downstream targets YAP and TAZ which are generall
PMID 27634386

Ouabain interactions with the α4 isoform of the sodium pump trigger non-classical steroid hormone signaling and integrin expression in spermatogenic cells.

Upmanyu N1, Dietze R1, Kirch U1, Scheiner-Bobis G2.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Nov;1863(11):2809-2819. doi: 10.1016/j.bbamcr.2016.09.001. Epub 2016 Sep 4.
In addition to the ubiquitous α1 isoform of the sodium pump, sperm cells also express a male-specific α4 isoform whose function has been associated with sperm motility, fertility, and capacitation. Here we investigate in the murine spermatogenic cell line GC-2 interactions of the α4 isoform with
PMID 27599714

Low dose ouabain stimulates NaK ATPase α1 subunit association with angiotensin II type 1 receptor in renal proximal tubule cells.

Ketchem CJ1, Conner CD1, Murray RD2, DuPlessis M3, Lederer ED4, Wilkey D3, Merchant M5, Khundmiri SJ6.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Nov;1863(11):2624-2636. doi: 10.1016/j.bbamcr.2016.07.008. Epub 2016 Aug 3.
Our laboratory has recently demonstrated that low concentrations of ouabain increase blood pressure in rats associated with stimulation of NaK ATPase activity and activation of the Src signaling cascade in NHE1-dependent manner. Proteomic analysis of human kidney proximal tubule cells (HKC11) sugges
PMID 27496272

A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair.

Tomida Junya,Itaya Akiko,Shigechi Tomoko,Unno Junya,Uchida Emi,Ikura Masae,Masuda Yuji,Matsuda Shun,Adachi Jun,Kobayashi Masahiko,Meetei Amom Ruhikanta,Maehara Yoshihiko,Yamamoto Ken-Ichi,Kamiya Kenji,Matsuura Akira,Matsuda Tomonari,Ikura Tsuyoshi,Ishiai Masamichi,Takata Minoru
Nucleic acids research 41(14), 6930-6941, 2013-08-01
… When DNA replication is stalled at sites of DNA damage, a cascade of responses is activated in the cell to halt cell cycle progression and promote DNA repair. … In cells lacking the core complex, ATR-mediated phosphorylation of two functional response targets, ATRIP and FANCI, is defective. …
NAID 120005323036

Functionally redundant protein phosphatase genes PTP2 and MSG5 co-regulate the calcium signaling pathway in Saccharomyces cerevisiae upon exposure to high extracellular calcium concentration(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)

Lavina Walter A.,Hermansyah,Sugiyama Minetaka,Kaneko Yoshinobu,Harashima Satoshi
Journal of bioscience and bioengineering 115(2), 138-146, 2013-02
… Reversible phosphorylation is one of the key post-translational modifications for the regulation of many essential cellular processes. … In the wake of a calcium-induced, calcineurin-driven signaling pathway activation, the calcium sensitivity of the ptp2Δmsg5Δ double disruptant can be suppressed by regulating the SLT2 pathway through the disruption of the major kinases in the SLT2 signal cascade that include BCK1, MKK1 and SLT2. …
NAID 110009592561

Nobiletin Induces Inhibitions of Ras Activity and Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Signaling to Suppress Cell Proliferation in C6 Rat Glioma Cells

Aoki Koichi,Yokosuka Akihito,Mimaki Yoshihiro,Fukunaga Kohji,Yamakuni Tohru
Biological and Pharmaceutical Bulletin 36(4), 540-547, 2013
… Ras, a small G-protein, physiologically directs cell proliferation and cell cycle via regulation of mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) signaling cascade. …
NAID 130003361386