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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/06 22:11:15」(JST)

Phensuximide is an anticonvulsant in the succinimide class.

DDB 31648
Rankin G, Cressey-Veneziano K, Wang R, Brown P (1986). "Urinary tract effects of phensuximide in the Sprague-Dawley and Fischer 344 rat.". J Appl Toxicol 6 (5): 349–56. doi:10.1002/jat.2550060509. PMID 3772011.

This anticonvulsant-related article is a stub. You can help Wikipedia by expanding it.

[Synthesis and application of sulfonated beta-cyclodextrins as chiral additives in capillary electrophoresis].

Ruan ZQ1, You JM, Li JB, Ou QY.
Se pu = Chinese journal of chromatography / Zhongguo hua xue hui.Se Pu.2000 Mar;18(2):183-6.
Three new kinds of the sodium salt of sulfonated beta-cyclodextrins with different degrees of substitution were synthesized and characterized. A simple synthesis method was employed by direct sulfonating reaction with concentrated sulfuric acid. Sulfonated beta-cyclodextrins were used as chiral reso
PMID 12541606

Role of para-hydroxylation in phensuximide-induced urotoxicity in the Fischer 344 rat.

Rankin GO1, Beers KW, Nicoll DW, Anestis DK, Shih HC, Brown PI, Hubbard JL.
Toxicology.Toxicology.1992 Aug;74(1):77-88.
Phensuximide (PSX) is an antiepileptic agent which has been shown to induce hemorrhagic cystitis and mild nephrotoxicity following repeated administration in man or rats or when acutely administered to phenobarbital-pretreated rats. The purpose of this study was to explore the role of para-hydroxyla
PMID 1514190

Acute effects of the antiepileptic succinimides on the urinary tract and potentiation of phensuximide-induced urotoxicity by phenobarbital.

Rankin GO1, Teets VJ, Nicoll DW, Brown PI.
Journal of applied toxicology : JAT.J Appl Toxicol.1990 Jun;10(3):203-9.
Phensuximide (PSX), methsuximide (MSX) and ethosuximide (ESX) are succinimide antiepileptic agents used worldwide in the treatment of absence seizures. A previous study from our laboratory demonstrated that PSX (0.3 or 0.6 mmol kg-1 day-1, i.p.) induced urotoxicity following daily administration for
PMID 2380483

Phensuximide
Systematic (IUPAC) name
	1-methyl-3-phenyl-pyrrolidine-2,5-dione
Clinical data
MedlinePlus	a682237
Pharmacokinetic data
Protein binding	21%
Identifiers
CAS Registry Number	86-34-0
ATC code	N03AD02
PubChem	CID 6839
DrugBank	DB00832
ChemSpider	6578
UNII	6WVL9C355G
KEGG	D00508
ChEMBL	CHEMBL797
Chemical data
Formula	C11H11NO2
Molecular mass	189.211 g/mol
	SMILES O=C2N(C(=O)CC2c1ccccc1)C;
	InChI InChI=1S/C11H11NO2/c1-12-10(13)7-9(11(12)14)8-5-3-2-4-6-8/h2-6,9H,7H2,1H3 ; Key:WLWFNJKHKGIJNW-UHFFFAOYSA-N ;
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