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  • Effects of metformin, buformin, and phenformin on the post-initiation stage of chemically induced mammary carcinogenesis in the rat.
  • Zhu Z1, Jiang W1, Thompson MD2, Echeverria D1, McGinley JN1, Thompson HJ3.
  • Cancer prevention research (Philadelphia, Pa.).Cancer Prev Res (Phila).2015 Jun;8(6):518-27. doi: 10.1158/1940-6207.CAPR-14-0121. Epub 2015 Mar 24.
  • Metformin is a widely prescribed drug for the treatment of type II diabetes. Although epidemiologic data have provided a strong rationale for investigating the potential of this biguanide for use in cancer prevention and control, uncertainty exists whether metformin should be expected to have an imp
  • PMID 25804611
  • Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype.
  • Cuyàs E1,2, Fernández-Arroyo S3, Corominas-Faja B1,2, Rodríguez-Gallego E3, Bosch-Barrera J2,4, Martin-Castillo B2,5, De Llorens R6, Joven J3, Menendez JA1,2.
  • Oncotarget.Oncotarget.2015 May 20;6(14):12279-96.
  • Metabolic flexibility might be particularly constrained in tumors bearing mutations in isocitrate dehydrogenase 1 (IDH1) leading to the production of the oncometabolite 2-hydroxygluratate (2HG). To test the hypothesis that IDH1 mutations could generate metabolic vulnerabilities for therapeutic inter
  • PMID 25980580
  • Immunohistochemical localization of OCT2 in the cochlea of various species.
  • Hellberg V1, Gahm C, Liu W, Ehrsson H, Rask-Andersen H, Laurell G.
  • The Laryngoscope.Laryngoscope.2015 Apr 17. doi: 10.1002/lary.25304. [Epub ahead of print]
  • OBJECTIVE: To locate the organic cation transporter 2 (OCT2) in the cochlea of three different species and to modulate the ototoxicity of cisplatin in the guinea pig by pretreatment with phenformin, having a known affinity for OCT2.STUDY DESIGN: Immunohistochemical and in vivo study.METHODS: Section
  • PMID 25892279


  • Analysis of Drugs Illegally Added into Chinese Traditional Patent Medicine Using Surface-enhanced Raman Scattering
  • ZHANG Yan,HUANG Xiaoyan,LIU Wenfang,CHENG Zeneng,CHEN Chuanpin,YIN Lihui
  • Analytical Sciences 29(10), 985-990, 2013
  • … In this report, a surface-enhanced Raman scattering (SERS) analysis method for five kinds of illegally added drugs (rosiglitazone maleate, phenformin hydrochloride, metformin hydrochloride, pioglitazone hydrochloride and sibutramine hydrochloride) in Chinese traditional patent medicine (CTPM) has been demonstrated, including simultaneous detections of drug mixtures with CTPM. …
  • NAID 130004442154
  • フェンホルミンのミトコンドリア毒性に対する有機カチオン輸送系の関与
  • 則岡 美咲,設楽 悦久,堀江 利治
  • 日本薬物動態学会年会講演要旨集 24(0), 115-115, 2009
  • NAID 130004639485
  • Comparison of gene expression changes induced by biguanides in db/db mice liver
  • Heishi Masayuki,Hayashi Koji,Ichihara Junji [他],Ishikawa Hironori,Kawamura Takao,Kanaoka Masaharu,Taiji Mutsuo,Kimura Toru
  • Journal of toxicological sciences 33(3), 339-347, 2008-08-01
  • … By contrast, another biguanide, phenformin, has been withdrawn from major markets because of a high incidence of serious adverse effects. … To gain insight into the different modes of action of the two drugs, we performed global gene expression pro filing using the livers of obese diabetic db/db mice after a single administration of phenformin or metformin at levels sufficient to cause a significant reduction in blood glucose level. …
  • NAID 110006862210


phenformin (fɛnˈfɔːmɪn) n (Pharmacology) a biguanide administered orally in the treatment of diabetes to lower blood concentrations of glucose; it has been ... Several other more potent biguanides were also developed, including phenformin ...
Phenforminとは?goo Wikipedia (ウィキペディア) 。出典:Wikipedia(ウィキペディア)フリー百科事典。 Phenforminとは - goo Wikipedia (ウィキペディア) gooトップ サイトマップ スタートページに設定 RSS ヘルプ メニューへスキップ 本文へ ...


Posted by Sara Fazio • August 22nd, 2014Description Phenformin.svgDiabetes Drugs: Metformin - Diabetes Self Phenformin; FenforminPhenformin has the potential & Obesity / Phenformin hydrochloride




フェネチルビグアニド phenethylbiguanide