出典: meddic

  • adj.
  • 薬力学的な、薬力学の

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/04/15 02:34:46」(JST)

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  • Enzymatic tumour tissue digestion coupled to SPE-UPLC-Tandem Mass Spectrometry as a tool to explore paclitaxel tumour penetration.
  • Colin P1, De Smet L2, De Bock L3, Goeteyn W3, Boussery K3, Vervaet C2, Van Bocxlaer J3.
  • Talanta.Talanta.2014 Nov;129:119-25. doi: 10.1016/j.talanta.2014.05.028. Epub 2014 May 24.
  • Paclitaxel is a good compound for regional (intraperitoneal) chemotherapy of peritoneal carcinomatosis. During IPEC, a cytotoxic solution is circulated in the peritoneal cavity, thereby promoting close contact between the cytotoxic agent and the exposed (residual) tumour tissue. To further explore t
  • PMID 25127573
  • Dose-dependent model of caffeine effects on human vigilance during total sleep deprivation.
  • Ramakrishnan S1, Laxminarayan S1, Wesensten NJ2, Kamimori GH2, Balkin TJ2, Reifman J3.
  • Journal of theoretical biology.J Theor Biol.2014 Oct 7;358:11-24. doi: 10.1016/j.jtbi.2014.05.017. Epub 2014 May 20.
  • Caffeine is the most widely consumed stimulant to counter sleep-loss effects. While the pharmacokinetics of caffeine in the body is well-understood, its alertness-restoring effects are still not well characterized. In fact, mathematical models capable of predicting the effects of varying doses of ca
  • PMID 24859426
  • Preliminary studies on trigonelline as potential anti-Alzheimer disease agent: Determination by hydrophilic interaction liquid chromatography and modeling of interactions with beta-amyloid.
  • Makowska J1, Szczesny D2, Lichucka A3, Giełdoń A4, Chmurzyński L5, Kaliszan R6.
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2014 Oct 1;968:101-4. doi: 10.1016/j.jchromb.2013.12.001. Epub 2013 Dec 12.
  • For trigonelline, a quaternary-base pyridine alkaloid of presumed Alzheimer's disease-preventing activity, a method of determination has been proposed, based on the hydrophilic interaction chromatography (HILIC). That method might be applied to study the agent's bioavailability, in particular its pe
  • PMID 24374010


  • Increased Platelet Inhibition After Switching From Maintenance Clopidogrel to Prasugrel in Japanese Patients With Stable Coronary Artery Disease
  • Nishi Takeshi,Ariyoshi Noritaka,Nakayama Takashi,Fujimoto Yoshihide,Sugimoto Kazumasa,Takahara Masayuki,Wakabayashi Shinichi,Koshizaka Masaya,Hanaoka Hideki,Kobayashi Yoshio
  • Circulation Journal advpub(0), 2015
  • … Background:The pharmacodynamic effects of changing from standard-dose clopidogrel to low-dose (3.75 mg) prasugrel in Japanese patients are largely unknown.Methods and Results:A total of 53 consecutive Japanese patients with stable coronary artery disease (CAD) who received aspirin and clopidogrel were enrolled. …
  • NAID 130005095329
  • Pharmacokinetic–Pharmacodynamic Analysis of Sunitinib-Induced Thrombocytopenia in Japanese Patients with Renal Cell Carcinoma
  • Nagata Masashi,Ishiwata Yasuyoshi,Takahashi Yutaka [他],Takahashi Hiromitsu,Saito Kazutaka,Fujii Yasuhisa,Kihara Kazunori,Yasuhara Masato
  • Biological and Pharmaceutical Bulletin 38(3), 402-410, 2015
  • … The aim of the present study was to clarify the therapeutic range and adequate dose of sunitinib in Japanese renal cell carcinoma patients by means of a pharmacokinetic–pharmacodynamic analysis of sunitinib-induced thrombocytopenia. … Changes in platelet counts were fit to the pharmacokinetic–pharmacodynamic model, in which the proliferation of platelet progenitor cells was assumed to be linearly inhibited by sunitinib and its metabolite. …
  • NAID 130004872283
  • Pharmacodynamic Comparison of Pitavastatin Versus Atorvastatin on Platelet Reactivity in Patients With Coronary Artery Disease Treated With Dual Antiplatelet Therapy : The PORTO Trial
  • Pelliccia Francesco,Rosano Giuseppe,Marazzi Giuseppe [他]
  • Circulation journal : official journal of the Japanese Circulation Society 78(3), 679-684, 2014-03
  • NAID 40019991492


Definition of pharmacodynamic in the Medical Dictionary. pharmacodynamic explanation. Information about pharmacodynamic in Free online English dictionary. What is pharmacodynamic? Meaning of pharmacodynamic medical ...
I have been teaching modeling and simulation for several years. By itself, Chapter 1: "The Art of Modeling", is simply an excellent overview of the topic; and not only applies to pharmacokinetic-pharmacodynamic modeling, but to ...


Pharmacokinetic-Pharmacodynamic Modelling Figure 2. Integrative pharmacodynamic and  pharmacodynamic model for patients withconcept of pharmacokinetic pharmacodynamic Pharmacokinetic/pharmacodynamic parameters Pharmacokinetic and Pharmacodynamic







  • adj.
  • 薬力学的な