出典: meddic


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「a cell that engulfs and digests debris and invading microorganisms」
scavenger cell

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/09/12 19:08:28」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2018/04/26 23:08:02」(JST)

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  • Polymeric microparticles for sustained and local delivery of antiCD40 and antiCTLA-4 in immunotherapy of cancer.
  • Rahimian S1, Fransen MF2, Kleinovink JW2, Amidi M1, Ossendorp F3, Hennink WE4.
  • Biomaterials.Biomaterials.2015 Aug;61:33-40. doi: 10.1016/j.biomaterials.2015.04.043. Epub 2015 May 17.
  • This study investigated the feasibility of the use of polymeric microparticles for sustained and local delivery of immunomodulatory antibodies in immunotherapy of cancer. Local delivery of potent immunomodulatory antibodies avoids unwanted systemic side effects while retaining their anti-tumor effec
  • PMID 25993015
  • The anti-inflammatory effects of acetaminophen and N-acetylcysteine through suppression of the NLRP3 inflammasome pathway in LPS-challenged piglet mononuclear phagocytes.
  • Liu Y1, Yao W2, Xu J2, Qiu Y3, Cao F2, Li S2, Yang S2, Yang H2, Wu Z1, Hou Y1.
  • Innate immunity.Innate Immun.2015 Aug;21(6):587-97. doi: 10.1177/1753425914566205. Epub 2015 Jan 8.
  • Acetaminophen (AAP) and N-acetylcysteine (NAC) have been found to have anti-inflammatory effects via the TLR-NF-κB pathway in LPS-challenged piglets. However, the action mechanisms employed by AAP and NAC have yet to be completely understood. This study investigated the anti-inflammatory effects an
  • PMID 25575547
  • Functional roles and gene regulation of tumor necrosis factor receptor 1 in freshwater striped murrel.
  • Palanisamy R1, Kumaresan V1, Harikrishnan R2, Arasu MV3, Al-Dhabi NA3, Arockiaraj J4.
  • Molecular immunology.Mol Immunol.2015 Aug;66(2):240-52. doi: 10.1016/j.molimm.2015.03.015. Epub 2015 Apr 1.
  • In this study, a complete molecular characterization of tumor necrosis factor receptor 1 (TNFR1) which was identified from the constructed cDNA library of striped murrel Channa striatus (Cs) is reported. The CsTNFR1 encoded a type I membrane receptor protein that contains 399 amino acids including t
  • PMID 25841174


  • Effects of Repeated Intravenous Administration of Dextrans, Water-soluble Macromolecules, in Rats
  • Kitazawa Ikue,Ito Shino,Kagawa Yusuke [他]
  • Journal of toxicologic pathology 27(3・4), 231-234, 2014
  • NAID 40020258365
  • Nanoparticle-Mediated Drug Delivery System for Cardiovascular Disease
  • Matoba Tetsuya,Egashira Kensuke
  • International Heart Journal 55(4), 281-286, 2014
  • … Nano-scale materials modify in vivo drug kinetics, depending on (patho)physiological mechanisms such as vascular permeability and incorporation by the mononuclear phagocyte system, which constitute 'passive-targeting' properties of nano-DDS. …
  • NAID 130004941279
  • Effects of Repeated Intravenous Administration of Dextrans,Water-soluble Macromolecules, in Rats
  • Kitazawa Ikue,Ito Shino,Kagawa Yusuke,Suehiro-Narita Miki,Hashizume Naoto,Minamisawa Yuka,Nii Aisuke,Kawakami Akio,Nakajima Shinichi
  • Journal of Toxicologic Pathology 27(3+4), 231-234, 2014
  • … Histopathological changes indicating accumulation of DEXs in the mononuclear phagocyte system (MPS) and the liver were noted in the treated groups. …
  • NAID 130004713009


Phagocytes are the white blood cells that protect the body by ingesting ( phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, "to eat" or "devour", and "-cyte", the suffix in biology ...



拡張検索fixed phagocyte」「free phagocyte」「alveolar phagocyte」「mononuclear phagocyte system



[show details]

食細胞表面レセプター (SMB.38)

リガンド種 受容体 CD リガンド 発現
抗体 FcγRI CD64 IgG3, IgG1, IgG4 マクロファージ
FcγRII CD32 IgG3, IgG1, IgG2 多核白血球
FcγRIII CD16 IgG1, IgG3  
補体 CR1 CD35 C3b  
CR3 CD11b/CD18 iC3b  
CR4 CD11c/CD18 iC3b  



  • adj.
  • 食作用性の、食作用の、食細胞の

WordNet   license wordnet

「capable of functioning as a phagocyte」




fixed phagocyte」


WordNet   license wordnet

「a phagocyte that does not circulate in the blood but is fixed in the liver or spleen or bone marrow etc.」

free phagocyte」


WordNet   license wordnet

「a phagocyte that circulates in the blood」

alveolar phagocyte」

  [★] 肺胞マクロファージ。肺胞大食細胞

mononuclear phagocyte system」

  [★] 単核性貧食細胞系