WordNet

related to the key issue but not of central importance; "a peripheral interest"; "energy is far from a peripheral issue in the economy"; "peripheral issues"
(computer science) electronic equipment connected by cable to the CPU of a computer; "disk drives and printers are important peripherals" (同)computer peripheral, peripheral device
on or near an edge or constituting an outer boundary; the outer area; "Russias peripheral provinces"; "peripheral suburbs"
amide combining the amino group of one amino acid with the carboxyl group of another; usually obtained by partial hydrolysis of protein

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Naef L1, Pitman KA1, Borgland SL1.
CNS spectrums.CNS Spectr.2015 Dec;20(6):574-83. doi: 10.1017/S1092852915000693. Epub 2015 Oct 30.
Obesity has reached epidemic prevalence, and much research has focused on homeostatic and nonhomeostatic mechanisms underlying overconsumption of food. Mesocorticolimbic circuitry, including dopamine neurons of the ventral tegmental area (VTA), is a key substrate for nonhomeostatic feeding. The goal
PMID 26514168

Role of the clock gene Bmal1 and the gastric ghrelin-secreting cell in the circadian regulation of the ghrelin-GOAT system.

Laermans J1, Vancleef L1, Tack J1, Depoortere I1.
Scientific reports.Sci Rep.2015 Nov 18;5:16748. doi: 10.1038/srep16748.
As adequate food intake is crucial to survival, organisms have evolved endogenous circadian clocks to generate optimal temporal patterns of food-related behavior and physiology. The gastric ghrelin-secreting cell is thought to be part of this network of peripheral food-entrainable oscillators (FEOs)
PMID 26576661

PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin.

Vu JP1, Goyal D2, Luong L3, Oh S1, Sandhu R1, Norris J1, Parsons W4, Pisegna JR5, Germano PM6.
American journal of physiology. Gastrointestinal and liver physiology.Am J Physiol Gastrointest Liver Physiol.2015 Nov 15;309(10):G816-25. doi: 10.1152/ajpgi.00190.2015. Epub 2015 Sep 3.
Pituitary adenylate cyclase-activating peptide (PACAP) is expressed within the gastroenteric system, where it has profound physiological effects. PACAP was shown to regulate food intake and thermogenesis centrally; however, PACAP peripheral regulation of appetite and feeding behavior is unknown. The
PMID 26336928

Toshinai Koji
The Journal of Physical Fitness and Sports Medicine 2(1), 69-75, 2013
… The gastrointestinal tract secretes several peptide hormones that regulate food intake by transmitting signals to the central nervous system related to energy homeostasis. … Eating disorders are considered to be caused by a breakdown in the food intake regulatory system of the central nervous system and the peripheral nervous system; …
NAID 130003379944

Association of exercise with appetite and energy intake through endocrine mechanism

Yoshikawa Takahiro,Fujimoto Shigeo
The Journal of Physical Fitness and Sports Medicine 1(2), 211-217, 2012
… The hormone family is divided into two categories: orexigenic ghrelin and anorexic hormones, such as peptide YY (PYY), and glucagon-like peptide-1 (GLP-1). … These endocrine signals interact not only with the hypothalamus, but also with higher neural circuits including the prefrontal cortex and insula, suggesting tight linkages between peripheral and central appetite systems. …
NAID 130001930860

成尾鉄朗
心身医学 43(10), 671-677, 2003-10-01
成長ホルモン分泌促進因子受容体の内因性リガンドとして探索がなされ,ラットの胃から発見されたプレリンは,強力な成長ホルモン分泌刺激作用を有するばかりでなく,摂食も強力に亢進させ,他に循環器系や中枢神経系,骨代謝系などでさまざまな生理作用を有することが判明している.特に,飢餓や空腹において,胃を中心にグレリンの多くが未梢臓器で分泌されて全身循環の中で,延髄の迷走神経核を介して末梢から視床下部への求心路 …
NAID 110001114374