WordNet

resulting from or employing derivation; "a derivative process"; "a highly derivative prose style"
a compound obtained from, or regarded as derived from, another compound
(linguistics) a word that is derived from another word; "`electricity is a derivative of `electric"
any of various antibiotics obtained from Penicillium molds (or produced synthetically) and used in the treatment of various infections and diseases

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Profiling of β-Lactam Selectivity for Penicillin-Binding Proteins in Streptococcus pneumoniae D39.

Kocaoglu O1, Tsui HC2, Winkler ME3, Carlson EE4.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Jun;59(6):3548-55. doi: 10.1128/AAC.05142-14. Epub 2015 Apr 6.
Selective fluorescent β-lactam chemical probes enable the visualization of the transpeptidase activity of penicillin-binding proteins (PBPs) at different stages of bacterial cell division. To facilitate the development of new fluorescent probes for PBP imaging, we evaluated 20 commercially availabl
PMID 25845878

Profiling of β-Lactam Selectivity for Penicillin-Binding Proteins in Escherichia coli Strain DC2.

Kocaoglu O1, Carlson EE2.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 May;59(5):2785-90. doi: 10.1128/AAC.04552-14. Epub 2015 Mar 2.
Penicillin-binding proteins (PBPs) are integral players in bacterial cell division, and their catalytic activities can be monitored with β-lactam-containing chemical probes. Compounds that target a single PBP could provide important information about the specific role(s) of each enzyme, making iden
PMID 25733506

Selective immediate responders to amoxicillin and clavulanic acid tolerate penicillin derivative administration after confirming the diagnosis.

Blanca-Lopez N1, Perez-Alzate D1, Ruano F1, Garcimartin M1, de la Torre V1, Mayorga C1, Somoza ML1, Perkins J1, Blanca M2, Canto MG1, Torres MJ2.
Allergy.Allergy.2015 Apr 24. doi: 10.1111/all.12636. [Epub ahead of print]
BACKGROUND: An increasing number of patients show immediate selective hypersensitivity reactions to clavulanic acid (CLV) and amoxicillin (AX), probably due to their increased prescription. The maintenance of this response should be established.OBJECTIVE: To assess that the immediate hypersensitivit
PMID 25913298

Study on the Stevioside Analogues of Steviolbioside, Steviol, and Isosteviol 19-Alkyl Amide Dimers : Synthesis and Cytotoxic and Antibacterial Activity

Lin Lun-Huei,Lee Lin-Wen,Sheu Shiow-Yunn [他],LIN Pen-Yuan
Chemical & pharmaceutical bulletin 52(9), 1117-1122, 2004-09-01
… Compounds 2f, 2g and 4 of this series had favorable antibacterial effects, and were superior to penicillin G at inhibiting growth of Bacillus subtilis (BCRC 10029). … The cytotoxicity and antibacterial effects may depend on the dimerization and derivative moieties in relation to the respective aglycons. …
NAID 110003615731

Novel S-Benzylisothiourea Compound That Induces Spherical Cells in Escherichia coli Probably by Acting on a Rod-shape-determining Protein(s) Other Than Penicillin-binding Protein 2(Microbiology & Fermentation Technology)

Iwai Noritaka,Nagai Kazuo,Wachi Masaaki
Bioscience, biotechnology, and biochemistry 66(12), 2658-2662, 2002-12-23
… A novel S-benzylisothiourea derivative, S- (3, 4-dichlorobenzyl) isothiourea, tentatively named A22, was found to induce spherical cells and spherical anucleate cells in E. … Mecillinam, a specific inhibitor of penicillin-binding protein 2, which induces spherical cells in E. …
NAID 110002693615

石黒正路,西原達郎,田中里枝
藥學雜誌 121(12), 915-927, 2001-12-01
… Modeling of a complex of faropenem at the active site of a penicillin-binding protein 2(PBP2) model suggested the characteristic affinity for faropenem with PBP2 of Escherichia coli. … The synthetic intermediate, a 3-hydroxyethyl-4-acetoxyazetidinone derivative, was efficiently prepared by the 2+2 coupling of a optically active vinylsulfide derivative and chlorosulfonyl isocyanate, followed by the substitution of the acetoxy group for the thiophenyl group at the C-4 position. …
NAID 110003648499