WordNet

affected with paralysis (同)paralyzed
a person suffering from paralysis
relating to or of the nature of paralysis; "paralytic symptoms" (同)paralytical
mental deterioration of organic or functional origin (同)dementedness

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麻痺した,中風の;《英話》泥酔した / 〈C〉中風患者
(医学的な)痴呆(ちほう)

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1. 前頭側頭型認知症：疫学、病理学、および病因 frontotemporal dementia epidemiology pathology and pathogenesis
2. 重度認知症患者の緩和ケア palliative care of patients with advanced dementia
3. パーキンソン病による認知症 parkinson disease dementia
4. レビー小体型認知症の臨床的特徴および診断 clinical features and diagnosis of dementia with lewy bodies
5. 認知症に関連する行動症状の治療 treatment of behavioral symptoms related to dementia

English Journal

A case of neurosyphilis revealed by acute exudative polymorphous vitelliform maculopathy.

Wolff B, Mrejen S, Freund KB, Titah C, Mauget-Faÿsse M.AbstractThe authors report the case of a healthy 56-year-old man presenting with bilateral vision loss. Clinical features were consistent with the diagnosis of acute exudative polymorphous vitelliform maculopathy (AEPVM). The patient returned 10 days later with bilateral anterior granulomatous uveitis, and the inflammatory work-up revealed treponemal antibodies in the serum and spinal fluid, consistent with a diagnosis of active neurosyphilis. The patient received standard treatment for neurosyphilis with intravenous penicillin G. Two months later, the intraocular inflammation had resolved, but the resolution of the vitelliform lesions was more gradual. An immune process could be a plausible explanation for these clinical findings. Clinicians should be aware that syphilis can produce AEPVM. [Ophthalmic Surg Lasers Imaging Retina. 2014;45:e29-e31.].
Ophthalmic surgery, lasers & imaging retina.Ophthalmic Surg Lasers Imaging Retina.2014 Apr 4;45(3):e29-31. doi: 10.3928/23258160-20140331-06.
The authors report the case of a healthy 56-year-old man presenting with bilateral vision loss. Clinical features were consistent with the diagnosis of acute exudative polymorphous vitelliform maculopathy (AEPVM). The patient returned 10 days later with bilateral anterior granulomatous uveitis, and
PMID 24695048

Late latent syphilis in a patient with end-stage renal disease and presumptive penicillin allergy.

Grice KT1, Day SA.Author information 1Karen T. Grice, Pharm.D., is Clinical Pharmacist, Department of Pharmacy, Grant Medical Center, Columbus, OH; at the time of writing, she was Pharmacy Practice Resident, Grant Medical Center. Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy, Doctors Hospital, Columbus.AbstractPURPOSE: Pharmacotherapy challenges in a case of late latent syphilis complicated by end-stage renal disease and presumptive penicillin allergy are described.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.Am J Health Syst Pharm.2014 Apr 1;71(7):558-61. doi: 10.2146/ajhp130345.
PURPOSE: Pharmacotherapy challenges in a case of late latent syphilis complicated by end-stage renal disease and presumptive penicillin allergy are described.SUMMARY: A 58-year-old white woman was admitted to the hospital for symptoms including altered mental status, shortness of breath, and chest p
PMID 24644115

Syphilis and HIV co-infection: excellent response to multiple doses of benzathine penicillin.

Saje A1, Tomažič J2.Author information 1Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre Ljubljana, Ljubljana, Slovenia. Corresponding author: sajecka@gmail.com.2Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre Ljubljana, Ljubljana, Slovenia.AbstractBackground: The number of new syphilis diagnoses in Slovenia is steadily increasing, especially among HIV-infected men who have sex with men (MSM). We studied the effect of penicillin for treating syphilis in HIV co-infected patients and risk factors for treatment failure. The primary endpoint was response to therapy (fourfold reduction of VDRL at month 12). Methods: Three hundred forty-two paper records were reviewed and MSM with positive VDRL and/or TPHA and serological follow up of at least 12 months were enrolled in the survey. Results: Incidence of syphilis increased from 1.2% (2005) and 2.9% (2007) to 6.4% (2009) and 3.8% (2011, until July). Two hundred sixty-one (76.3%) were MSM and 102 (29.8%) were co-infected; 54.0% had primary/secondary syphilis, 37.0% latent syphilis, and 9.0% neurosyphilis. Patients with primary/secondary/latent syphilis were treated with three doses of benzathine penicillin (2.4 MU i.m.). Treatment was successful in 92.2%. With respect to risk factors, there was no difference between the "success" and "failure" group. Twenty-six patients (25.5%) had re-infections. Conclusions: Therate of cure in our study population was excellent, probably due to a low degree of immunosuppression and a three-dose benzathine penicillin regimen.
Acta dermatovenerologica Alpina, Panonica, et Adriatica.Acta Dermatovenerol Alp Panonica Adriat.2014 Mar;23(1):1-3.
Background: The number of new syphilis diagnoses in Slovenia is steadily increasing, especially among HIV-infected men who have sex with men (MSM). We studied the effect of penicillin for treating syphilis in HIV co-infected patients and risk factors for treatment failure. The primary endpoint was r
PMID 24638864