WordNet

small room in which a monk or nun lives (同)cubicle
a device that delivers an electric current as the result of a chemical reaction (同)electric cell
a room where a prisoner is kept (同)jail cell, prison cell
(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
any small compartment; "the cells of a honeycomb"
a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
the 2nd letter of the Roman alphabet (同)b
the blood group whose red cells carry the B antigen (同)type_B, group B
of or involving the pancreas; "pancreatic cancer"

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. インスリン分泌および膵β細胞の機能 insulin secretion and pancreatic beta cell function
2. 糖尿病および遺伝的糖尿病症候群の分類 classification of diabetes mellitus and genetic diabetic syndromes
3. ケトーシス傾向のある糖尿病症候群 syndromes of ketosis prone diabetes mellitus
4. 小児および思春期における1型糖尿病の疫学、症状、および診断 epidemiology presentation and diagnosis of type 1 diabetes mellitus in children and adolescents
5. 幼児の持続性高インスリン血症性低血糖症の病因、臨床的特徴、および診断 pathogenesis clinical features and diagnosis of persistent hyperinsulinemic hypoglycemia of infancy

Identification of direct forkhead box O1 targets involved in palmitate-induced apoptosis in clonal insulin-secreting cells using chromatin immunoprecipitation coupled to DNA selection and ligation.

Lin HY, Yin Y, Zhang JX, Xuan H, Zheng Y, Zhan SS, Zhu YX, Han X.SourceKey Laboratory of Human Functional Genomics of Jiangsu Province, Department of Biochemistry and Molecular Biology, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China.
Diabetologia.Diabetologia.2012 Oct;55(10):2703-12. Epub 2012 Jul 20.
AIMS/HYPOTHESIS: The transcription factor, forkhead box (FOX)O1, is involved in fatty acid-induced apoptosis in pancreatic beta cells, but the precise mechanism is poorly understood. We aimed to identify which direct downstream targets of FOXO1 are involved in palmitate-induced apoptosis in the panc
PMID 22810813

Increased Expression of the Glucose-Responsive Gene, RCAN1, Causes Hypoinsulinemia, β-Cell Dysfunction, and Diabetes.

Peiris H, Raghupathi R, Jessup CF, Zanin MP, Mohanasundaram D, Mackenzie KD, Chataway T, Clarke JN, Brealey J, Coates PT, Pritchard MA, Keating DJ.SourceFlinders Medical Science and Technology and Centre for Neuroscience (H.P., R.R., C.F.J., M.P.Z., K.D.M., T.C., J.N.C., D.J.K.), Flinders University, Adelaide, Bedford Park SA 5042, Australia; School of Medicine (C.F.J., D.M., P.T.C.), University of Adelaide, Adelaide SA 5005, Australia; Australia Islet Consortium (D.M., P.T.C.), Institute of Medical and Veterinary Sciences (J.B.), Adelaide SA 5000, Australia; and Department of Biochemistry and Molecular Biology (M.A.P.), Monash University, Victoria 3842, Australia.
Endocrinology.Endocrinology.2012 Sep 25. [Epub ahead of print]
RCAN1 is a chromosome 21 gene that controls secretion in endocrine cells, regulates mitochondrial function, and is sensitive to oxidative stress. Regulator of calcineurin 1 (RCAN1) is also an endogenous inhibitor of the protein phosphatase calcineurin, the inhibition of which leads to hypoinsulinemi
PMID 23011918