pKa

出典: meddic

ionization statepK
  • pKaが小さいほど酸として強い


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/12/26 18:03:18」(JST)

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英文文献

  • A novel vasculo-angiogenic effect of cilostazol mediated by cross-talk between multiple signalling pathways including the ERK/p38 MAPK signalling transduction cascade.
  • Chao TH, Tseng SY, Li YH, Liu PY, Cho CL, Shi GY, Wu HL, Chen JH.Source§Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan.
  • Clinical science (London, England : 1979).Clin Sci (Lond).2012 Aug 1;123(3):147-59.
  • Cilostazol is an anti-platelet agent with vasodilatory activity that acts by increasing intracellular concentrations of cAMP. Recent reports have suggested that cilostazol may promote angiogenesis. In the present study, we have investigated the effect of cilostazol in promoting angiogenesis and vasc
  • PMID 22339730
  • Intercepting neoplastic progression in lung malignancies via the beta adrenergic (β-AR) pathway: Implications for anti-cancer drug targets.
  • Al-Wadei HA, Ullah MF, Al-Wadei MH.SourceExperimental Oncology Laboratory, Department of Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, TN 37996, USA; Sana'a University, Sana'a, Republic of Yemen.
  • Pharmacological research : the official journal of the Italian Pharmacological Society.Pharmacol Res.2012 Jul;66(1):33-40. Epub 2012 Apr 2.
  • The understanding of signaling cascades involved in the induction, promotion, and progression of cancer, although advanced in recent years, is still incomplete. Tracing the imbalance of the impaired, physiologically-essential cellular signaling that drives the neoplastic process is a complex issue.
  • PMID 22487140

和文文献

  • Deuterium kinetic isotope effects in heterotetrameric sarcosine oxidase from Corynebacterium sp. U-96 : the anionic form of the substrate in the enzymesubstrate complex is a reactive species
  • Saito Mutsumi,Itoh Ai,Suzuki Haruo
  • Journal of Biochemistry 151(6), 633-642, 2012-06
  • NAID 40019309991
  • Development of an optimized backbone of FRET biosensors for kinases and GTPases.
  • Komatsu Naoki,Aoki Kazuhiro,Yamada Masashi,Yukinaga Hiroko,Fujita Yoshihisa,Kamioka Yuji,Matsuda Michiyuki
  • Molecular biology of the cell 22(23), 4647-4656, 2011-12
  • … With this backbone system, we improved previously reported FRET biosensors of PKA, ERK, JNK, EGFR/Abl, Ras, and Rac1. …
  • NAID 120003644367

関連リンク

58K tweets • 1,042 photos/videos • 10.9K followers. Check out the latest Tweets from PKA (@PKAnzug) ... さすがに本当に小島さんを引き込んだ可能性は高くないと思うけど、小島さんがハリウッドに極めて強い憧れを持ってるのは自明だ ...
弱酸は,解離状態(A-)と非解離状態(AH)の間に,平衡が存在しており,酸解離定数(Ka)を持ちます。酸解離定数の対数にマイナスを付けたpKaが,溶液のpHと等しいとき,A-とAHは同濃度存在し,緩衝能が大きくなります。

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★リンクテーブル★
リンク元酸解離定数」「酸解離指数」「acid dissociation constant
関連記事PKA」「p

酸解離定数」

  [★]

acid dissociation constantpKa
酸解離指数


酸解離指数」

  [★]

(n
  • pKa
酸解離定数


acid dissociation constant」

  [★]

酸解離定数

pKa


PKA」

  [★]

A-kinasecAMP-dependent protein kinasecyclic AMP-dependent protein kinaseprotein kinase A
See Protein kinase A
Protein kinase A


p」

  [★]

10の-12乗
pico


"http://meddic.jp/pKa" より作成


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