出典: meddic


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「an oxidoreductase that catalyzes the incorporation of molecular oxygen」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/10/03 19:03:26」(JST)

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  • Targeting of heme oxygenase-1 as a novel immune regulator of neuroblastoma.
  • Fest S1,2, Soldati R1,3, Christiansen NM2, Zenclussen ML3, Kilz J1,3, Berger E1,3, Starke S2, Lode HN4, Engel C5, Zenclussen AC3, Christiansen H2.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2016 Apr 15;138(8):2030-42. doi: 10.1002/ijc.29933. Epub 2015 Dec 12.
  • Heme oxygenase (HO)-1 catalyzes the degradation of cytotoxic heme into biliverdin and blocks antitumor immune responses, thus protecting cancer against host defense. Whether this scenario also applies to neuroblastoma (NB), the most common extracranial solid childhood tumor, is not known. Here, we d
  • PMID 26595750
  • Effect of heme oxygenase-1 gene promoter polymorphism on cancer risk by histological subtype: A prospective study in arseniasis-endemic areas in Taiwan.
  • Wu MM1,2, Lee CH3, Hsu LI4, Cheng WF2, Lee TC5, Wang YH6,7, Chiou HY1, Chen CJ4.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2016 Apr 15;138(8):1875-86. doi: 10.1002/ijc.29926. Epub 2015 Nov 28.
  • Heme oxygenase (HO)-1 is upregulated by many stressful stimuli, including arsenic. A GT-repeat ((GT)n) polymorphism in the HO-1 gene promoter inversely modulates the levels of HO-1 induction. Previous HO-1 (GT)n polymorphism studies in relation to cancer risk have shown disparate results. We prospec
  • PMID 26566708
  • Heme oxygenase-1 alleviates cigarette smoke-induced restenosis after vascular angioplasty by attenuating inflammation in rat model.
  • Ni L1, Wang Z1, Yang G1, Li T1, Liu X1, Liu C2.
  • Toxicology letters.Toxicol Lett.2016 Mar 14;245:99-105. doi: 10.1016/j.toxlet.2016.01.017. Epub 2016 Jan 22.
  • Cigarette smoke is not only a profound independent risk factor of atherosclerosis, but also aggravates restenosis after vascular angioplasty. Heme oxygenase-1 (HO-1) is an endogenous antioxidant and cytoprotective enzyme. In this study, we investigated whether HO-1 upregulating by hemin, a potent HO
  • PMID 26809138


  • Ferrous Ferric Chloride Downregulates the Inflammatory Response to Rhodococcus aurantiacus Infection in Mice
  • Yimin,Tao Huirong,Kohanawa Masashi,Zhao Songji,Kuge Yuji,Tamaki Nagara
  • Biological and Pharmaceutical Bulletin 35(12), 2214-2223, 2012-12
  • … aurantiacus also induced the expression of heme oxygenase-1 mRNA in the cells from F1 mice. …
  • NAID 120005108194
  • Protective action of nipradilol mediated through S-nitrosylation of Keap1 and HO-1 induction in retinal ganglion cells
  • Koriyama Yoshiki,Kamiya Marie,Takadera Tsuneo,Arai Kunizo,Sugitani Kayo,Ogai Kazuhiro,Kato Satoru
  • Neurochemistry International 61(7), 1242-1253, 2012-12
  • … We also demonstrated that Nip induced the expression of the NO-dependent antioxidant enzyme, heme oxygenase-1 (HO-1). …
  • NAID 120004966623
  • ヘム分解産物が胃上皮細胞のVEGF産生と restitution に及ぼす効果
  • 恩田 健二,松井 裕史,平野 俊彦
  • 潰瘍 = Ulcer research 39(2), 136-138, 2012-09-20
  • NAID 10031061627


オキシゲナーゼ【oxygenase】とは。意味や解説、類語。酸化還元酵素の一。酸素分子中の酸素原子を基質に結合させる触媒となる。酸素添加酵素。酸素化酵素。 - goo国語辞書は27万語以上を収録。政治・経済・医学・ITなど、最新用語の ...
oxygenaseとは。意味や和訳。[名]《生化》酸素添加酵素. - goo英和辞書は14万項目以上を収録し、発音、音声、慣用句、例文が分かる英和辞書です。


 oxygenase-1 (HO-1) and further reaction to of human heme oxygenase-1 with bound hemeHeme oxygenase - Proteopedia, life in 3DFigure 1 . Heme oxygenaseHeme oxygenase in Chlamydomonas insights into human heme oxygenase

拡張検索cyclooxygenase-1」「arachidonate lipoxygenase









WordNet   license wordnet

「an enzyme that regulates prostaglandins that are important for the health of the stomach lining and kidneys; "an unfortunate side effect of NSAIDs is that they block Cox-1"」

arachidonate lipoxygenase」


  • アラキドン酸リ・キシゲナーゼ