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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/01/23 22:46:07」(JST)
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| Systematic (IUPAC) name |
| (2-hydroxyethyl)trimethylazanium; 1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-ide |
| Clinical data |
| AHFS/Drugs.com |
International Drug Names |
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Pregnancy
category
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| Legal status |
?
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| Identifiers |
| ATC code |
R03DA02 |
| PubChem |
CID 656652 |
| UNII |
3K045XR58X Y |
| ChEMBL |
CHEMBL1200434 |
| Synonyms |
Oxtriphylline, theocolin |
| Chemical data |
| Formula |
C12H21N5O3 |
| Molecular mass |
283.33 g/mol |
SMILES
- CN1C(=C2C(=NC=N2)N(C1=O)C)[O-].C[N+](C)(C)CCO
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InChI
-
InChI=1S/C7H8N4O2.C5H14NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-6(2,3)4-5-7/h3,12H,1-2H3;7H,4-5H2,1-3H3/q;+1/p-1
Key:SOELXOBIIIBLRJ-UHFFFAOYSA-M
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Choline theophyllinate (INN), also known as oxtriphylline, is a cough medicine derived from xanthine that acts as a bronchodilator to open up airways in the lung. Chemically, it is a salt of choline and theophylline. It classifies as an expectorant.[citation needed] The drug is available under the brand names Choledyl and Choledyl SA, among others.[1]
References
- ^ Drugs.com: Choledyl (oxtriphylline) medical facts
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Drugs for obstructive airway diseases: asthma/COPD (R03)
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| Adrenergics, inhalants |
| Short acting β2-agonists |
- Bitolterol
- Carbuterol
- Fenoterol
- Pirbuterol
- Procaterol
- Reproterol
- Rimiterol
- Salbutamol#/Levosalbutamol
- Terbutaline
- Tulobuterol
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| Long acting β2-agonists (LABA) |
- Arformoterol
- Bambuterol
- Clenbuterol
- Formoterol
- Salmeterol
- Ultra LABA: Indacaterol, Olodaterol, Vilanterol
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| other |
- Epinephrine#
- Hexoprenaline
- Isoprenaline (Isoproterenol)
- Orciprenaline (Metaproterenol)
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| Glucocorticoids |
- Beclometasone#
- Betamethasone
- Budesonide
- Ciclesonide
- Flunisolide
- Fluticasone
- Mometasone
- Triamcinolone
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Anticholinergics/
muscarinic antagonist |
- Aclidinium bromide
- Glycopyrronium bromide
- Ipratropium bromide#
- Oxitropium bromide
- Tiotropium bromide
- Umeclidinium bromide
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| Mast cell stabilizers |
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| Xanthines |
- Acefylline
- Ambuphylline
- Bamifylline
- Doxofylline
- Enprofylline
- Etamiphylline
- Proxyphylline
- Theobromine
- Theophylline/Aminophylline/Choline theophyllinate
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| Eicosanoid inhibition |
| Leukotriene antagonists |
- Montelukast
- Pranlukast
- Zafirlukast
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| Arachidonate 5-lipoxygenase inhibitors |
- Baicalein§
- Caffeic acid§
- Curcumin§
- Hyperforin§
- Meclofenamate sodium§
- St John's wort§
- Zileuton
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| Thromboxane receptor antagonists |
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| Non-xanthine PDE4 inhibitors |
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| Others/unknown |
- Amlexanox
- Eprozinol
- Fenspiride
- Omalizumab
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| Combination products |
- Budesonide/formoterol
- Fluticasone/salmeterol
- Ipratropium bromide/salbutamol
- Mometasone/formoterol
- Beclometasone/formoterol
- Fluticasone furoate/vilanterol
- Umeclidinium bromide/vilanterol
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of the respiratory system
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| Description |
- Anatomy
- Physiology
- Development
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| Disease |
- Congenital
- Neoplasms and cancer
- Chest trauma
- Infection
- Other
- Symptoms and signs
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| Treatment |
- Procedures
- Drugs
- nasal
- throat
- obstructive airway diseases
- cough and cold
- histaminergics
- other
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English Journal
- Revised FDA labeling guideline for theophylline oral dosage forms.
- Hendeles L1, Jenkins J, Temple R.
- Pharmacotherapy.Pharmacotherapy.1995 Jul-Aug;15(4):409-27.
- PMID 7479193
- Chemiluminometric determination of choline-related substances in pharmaceutical preparations by dot-blot.
- Luterotti S1, Maysinger D.
- Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.1994 Sep;12(9):1083-90.
- PMID 7803556
- The theophylline content of bronchodilator preparations on the South African market.
- Pillai G1, Miller R, Rambiritch V.
- South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.S Afr Med J.1991 Sep 7;80(5):240-3.
- PMID 1887352
Related Links
- oxtriphylline [oks-trif……´……ĭ-lēn] the choline salt of theophylline, used as a bronchodilator. oxtriphylline /ox·triph·yl·line/ (oks-trif´ĭ-lēn) the choline salt of theophylline, used chiefly as a bronchodilator. oxtriphylline [oks′trəfil′ēn] a ...
- Oxtriphylline is a bronchodilator. Oxtriphylline works in several ways: it relaxes muscles in your lungs and chest to allow more air in, decreases the sensitivity of your lungs to allergens and
Related Pictures
★リンクテーブル★
[★]
- 英
- choline theophylline、choline theophyllinate
- 同
- オクストリフィリン oxtriphylline、テオフィリン酸コリン コリンテオフィリネート choline theophyllinate
- 商
- テオコリン