WordNet
- an indicator that shows a reversible color change between oxidized and reduced forms
- any process in which electrons are added to an atom or ion (as by removing oxygen or adding hydrogen); always occurs accompanied by oxidation of the reducing agent (同)reducing
- the act of reducing complexity (同)simplification
- (chemistry) a substance that changes color to indicate the presence of some ion or substance; can be used to indicate the completion of a chemical reaction or (in medicine) to test for a particular reaction
- a device for showing the operating condition of some system
- a signal for attracting attention
- the process of oxidizing; the addition of oxygen to a compound with a loss of electrons; always occurs accompanied by reduction (同)oxidization, oxidisation
PrepTutorEJDIC
- 〈U〉〈C〉(…を)『減らすこと』,減少,縮小,格下げ,(…の)割り引き《+『in』+『名』》 / 〈C〉減少(縮小)した量;割引額 / 〈C〉縮図,縮写 / 〈U〉換算約分
- 指示する人(物),指示器,表示器;指針 / (リトマスなどの)指示薬
- 酸化
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Influence of the Redox Indicator Reaction on Single-Nanoparticle Collisions at Mercury- and Bismuth-Modified Pt Ultramicroelectrodes.
- Dasari R, Walther B, Robinson DA, Stevenson KJ.Author information Department of Chemistry, The University of Texas at Austin , 1 University Station, Austin, Texas 78712, United States.AbstractSingle-Pt nanoparticles (NPs) can be detected electrochemically by measuring the current-time (i-t) response associated with both hydrazine oxidation and proton reduction during individual Pt NP collisions with noncatalytic Hg- and Bi-modified Pt ultramicroelectrodes (Hg/Pt and Bi/Pt UMEs, respectively). At Hg/Pt UMEs, the i-t response for both hydrazine oxidation and proton reduction consists of repeated current "spikes" that return to the background level as Hg poisons the Pt NP after collision with the Hg/Pt UME due to amalgamation and deactivation of the redox reaction. Furthermore, at a Hg/Pt UME, the applied potential directly influences the interfacial surface tension (electrocapillarity) that also impacts the observed i-t response for single-Pt NP collisions for proton reduction that exhibits a faster decay of current (0.7-4 ms) to background levels than hydrazine oxidation (2-5 s). Because the surface tension of Hg is lower (-0.9 V), Pt NPs possibly react faster with Hg (amalgamate at a faster rate), resulting in sharp current spikes for proton reduction compared to hydrazine oxidation. In contrast, a stepwise "staircase" i-t response is observed for proton reduction for single-Pt NP collisions at a Bi/Pt UME. This different response suggests that electrostatic forces of negatively charged citrate-capped Pt NPs also influence the i-t response at more negative applied potentials, but the Pt NPs do not poison the electrochemical activity at Bi/Pt UMEs.
- Langmuir : the ACS journal of surfaces and colloids.Langmuir.2013 Nov 19. [Epub ahead of print]
- Single-Pt nanoparticles (NPs) can be detected electrochemically by measuring the current-time (i-t) response associated with both hydrazine oxidation and proton reduction during individual Pt NP collisions with noncatalytic Hg- and Bi-modified Pt ultramicroelectrodes (Hg/Pt and Bi/Pt UMEs, respectiv
- PMID 24188022
- Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice.
- Sheng L, Jiang B, Rui L.Author information Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan.AbstractThe liver is an essential metabolic organ. In addition to metabolizing glucose and lipids, hepatocytes also secrete various cytokines that modulate both hepatocyte metabolism and liver inflammation. Hepatocyte injury and death and liver inflammation are the major contributors to liver diseases, including nonalcoholic steatohepatitis (NASH). Anatomic locations have a profound effect on hepatocyte metabolism, and liver zonation describes the metabolic heterogeneity of hepatocytes along the portovenous axis. However, it is unclear whether hepatocyte heterogeneity is affected by intrinsic factors and whether dietary fat, a risk factor for NASH, has distinct detrimental effects on different hepatocyte subpopulations. Here, we showed that mouse livers contained both high-lipid and low-lipid subpopulations of hepatocytes. The high-lipid subpopulation was more susceptible to injury and apoptosis and produced more proinflamatrory cytokines after treatment with endotoxin and saturated fatty acids. Dietary fat consumption further increased fatty acid uptake, intracellular lipid levels, hepatocyte injury and death, and the expression of proinflammatory cytokines in the high-lipid subpopulation. In contrast, dietary fat slightly increased lipid levels, cell death, and expression of proinflammatory cytokines in the low-lipid subpopulation. The low-lipid subpopulation produced more glucose. Fat consumption further activated the gluconeogenic program in the low-lipid, but not the high-lipid, subpopulations. These data suggest that intracellular lipid content is a key intrinsic determinant for hepatocyte heterogeneity of metabolic, inflammatory, and survival states.
- American journal of physiology. Endocrinology and metabolism.Am J Physiol Endocrinol Metab.2013 Nov 1;305(9):E1115-23. doi: 10.1152/ajpendo.00401.2013. Epub 2013 Aug 27.
- The liver is an essential metabolic organ. In addition to metabolizing glucose and lipids, hepatocytes also secrete various cytokines that modulate both hepatocyte metabolism and liver inflammation. Hepatocyte injury and death and liver inflammation are the major contributors to liver diseases, incl
- PMID 23982157
- Rabbit 3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin D₂, and other endogenous and xenobiotic carbonyl compounds.
- Endo S, Matsunaga T, Matsumoto A, Arai Y, Ohno S, El-Kabbani O, Tajima K, Bunai Y, Yamano S, Hara A, Kitade Y.Author information Gifu Pharmaceutical University, Gifu 502-1196, Japan. Electronic address: sendo@gifu-pu.ac.jp.Abstract3-Hydroxyhexobarbital dehydrogenase (3HBD) catalyzes NAD(P)⁺-linked oxidation of 3-hydroxyhexobarbital into 3-oxohexobarbital. The enzyme has been thought to act as a dehydrogenase for xenobiotic alcohols and some hydroxysteroids, but its physiological function remains unknown. We have purified rabbit 3HBD, isolated its cDNA, and examined its specificity for coenzymes and substrates, reaction directionality and tissue distribution. 3HBD is a member (AKR1C29) of the aldo-keto reductase (AKR) superfamily, and exhibited high preference for NADP(H) over NAD(H) at a physiological pH of 7.4. In the NADPH-linked reduction, 3HBD showed broad substrate specificity for a variety of quinones, ketones and aldehydes, including 3-, 17- and 20-ketosteroids and prostaglandin D₂, which were converted to 3α-, 17β- and 20α-hydroxysteroids and 9α,11β-prostaglandin F₂, respectively. Especially, α-diketones (such as isatin and diacetyl) and lipid peroxidation-derived aldehydes (such as 4-oxo- and 4-hydroxy-2-nonenals) were excellent substrates showing low K(m) values (0.1-5.9 μM). In 3HBD-overexpressed cells, 3-oxohexobarbital and 5β-androstan-3α-ol-17-one were metabolized into 3-hydroxyhexobarbital and 5β-androstane-3α,17β-diol, respectively, but the reverse reactions did not proceed. The overexpression of the enzyme in the cells decreased the cytotoxicity of 4-oxo-2-nonenal. The mRNA for 3HBD was ubiquitously expressed in rabbit tissues. The results suggest that 3HBD is an NADPH-preferring reductase, and plays roles in the metabolisms of steroids, prostaglandin D₂, carbohydrates and xenobiotics, as well as a defense system, protecting against reactive carbonyl compounds.
- Biochemical pharmacology.Biochem Pharmacol.2013 Nov 1;86(9):1366-75. doi: 10.1016/j.bcp.2013.08.024. Epub 2013 Aug 27.
- 3-Hydroxyhexobarbital dehydrogenase (3HBD) catalyzes NAD(P)⁺-linked oxidation of 3-hydroxyhexobarbital into 3-oxohexobarbital. The enzyme has been thought to act as a dehydrogenase for xenobiotic alcohols and some hydroxysteroids, but its physiological function remains unknown. We have purified ra
- PMID 23994167
Japanese Journal
- Suppressive effect of rice bran incorporation in paddy soil on germination of Monochoria vaginalis and its relationship with electric conductivity(Soil fertility)
- NOZOE Takuhito,UCHINO Akira,OKAWA Shigenori [他],YOSHIDA Shuichi,KANDA Yukihide,NAKAYAMA Yukinori
- Soil science and plant nutrition 58(2), 200-205, 2012-04-00
- … There was no significant correlation between the oxidation-reduction potential (Eh) of soil and seed germination, suggesting that EC is a more reliable and convenient indicator than Eh for evaluating the relationship between the addition of organic material and seed germination. … Thus, it is expected that EC can be used as an indicator for determining how much rice bran to add. …
- NAID 110009592279
- 滴定法の変色反応を用いる目視-マイクロプレート法とその評価
- 間中 淳,石橋 真奈美,中山 彩 [他],中山 亜耶,野田 実穂,加藤 健,五十嵐 淑郎
- 分析化学 = Japan analyst 60(4), 363-366, 2011-04-05
- … Visual analysis by counting to number of changing color on a microplate was examined using the reaction used for several titration analysis (neutralization titration, oxidation-reduction titration and chelatometric titration). … After the addition of a sample to the microplate to which the several concentrations of a standard solution were added with the indicator at the each rows, the numbers of discoloring were changed with the sample concentration. …
- NAID 10028107149
- レドックス指示薬を用いた着床前マウス初期胚生存性の定量化の試み
- 小林 正之,佐々木 春佳,小笠原 杏子
- Journal of Reproduction and Development 47(2), 113-118, 2001
- … Alamar Blue, an oxidation-reduction indicator, added to a culture medium is reduced in living cells as an intermediate electron acceptor in the mitochondrial electron transport system, so that the absorbance of alamar Blue at a specific wavelength changes with the progression of cell growth or the number of living cells. …
- NAID 130000055036
Related Links
- Thesaurus Antonyms Related Words Synonyms Legend: Noun 1. oxidation-reduction indicator - an indicator that shows a reversible color change between oxidized and reduced forms indicator - (chemistry) a substance that changes ...
- ox·i·da·tion-re·duc·tion in·di·ca·tor a substance that undergoes a definite color change at a specific oxidation potential. Synonym(s): redox indicator ... Disclaimer All content on this website, including dictionary, thesaurus, literature ...
★リンクテーブル★
[★]
- 関
- decline、decrease、depression、diminish、diminution、down-regulate、down-regulation、downregulate、downregulation、drop、fall、hypoergy、loss、lower、lowering、parsimony、reduce、retrenchment
[★]
- 関
- index、indication、indices、reagent
[★]
- 関
- oxidised、oxidizable、oxidization、oxidize