有機アニオントランスポーター OATs
WordNet
- simple and healthful and close to nature; "an organic lifestyle"
- a fertilizer that is derived from animal or vegetable matter (同)organic fertilizer, organic fertiliser
- being or relating to or derived from or having properties characteristic of living organisms; "organic life"; "organic growth"; "organic remains found in rock"
- involving or affecting physiology or bodily organs; "an organic disease"
- of or relating to foodstuff grown or raised without synthetic fertilizers or pesticides or hormones; "organic eggs"; "organic vegetables"; "organic chicken"
- relating or belonging to the class of chemical compounds having a carbon basis; "hydrocarbons are organic compounds"
- wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
- a fully differentiated structural and functional unit in an animal that is specialized for some particular function
- a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
- a periodical that is published by a special interest group; "the organ of the communist party"
- a long truck for carrying motor vehicles (同)car transporter
- a crane for moving material with dispatch as in loading and unloading ships
- a negatively charged ion
- black tropical American cuckoo
PrepTutorEJDIC
- 有機体の,生物の,生物から生じた / (動植物の)器官の / 有機肥料を用いる(を用いて育った)・有機的な,組織的な,系統的な・有機質の
- 『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関
- 自動車運搬用大型トラック
- 陰イオン
UpToDate Contents
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English Journal
- Bezafibrate-mizoribine interaction: Involvement of organic anion transporters OAT1 and OAT3 in rats.
- Feng Y1, Wang C2, Liu Q2, Meng Q2, Huo X2, Liu Z2, Sun P2, Yang X2, Sun H2, Qin J3, Liu K4.
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2016 Jan 1;81:119-28. doi: 10.1016/j.ejps.2015.10.008. Epub 2015 Oct 22.
- A patient with rheumatoid arthritis developed rhabdomyolysis while undergoing treatment with mizoribine concomitantly with bezafibrate. The symptoms rapidly disappeared and laboratory test results normalized when she discontinued the two drugs. The purpose of the present study was to elucidate the t
- PMID 26474691
- Application of physiologically-based pharmacokinetic modeling to explore the role of kidney transporters in renal reabsorption of perfluorooctanoic acid in the rat.
- Worley RR1, Fisher J2.
- Toxicology and applied pharmacology.Toxicol Appl Pharmacol.2015 Dec 15;289(3):428-41. doi: 10.1016/j.taap.2015.10.017. Epub 2015 Nov 6.
- Renal elimination and the resulting clearance of perfluorooctanoic acid (PFOA) from the serum exhibit pronounced sex differences in the adult rat. The literature suggests that this is largely due to hormonally regulated expression of organic anion transporters (OATs) on the apical and basolateral me
- PMID 26522833
- Casein Kinase 2 Is a Novel Regulator of the Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) Trafficking.
- Chan T1, Cheung FS1, Zheng J2, Lu X1, Zhu L3, Grewal T1, Murray M4, Zhou F1.
- Molecular pharmaceutics.Mol Pharm.2015 Dec 4. [Epub ahead of print]
- Human organic anion transporting polypeptides (OATPs) mediate the influx of many important drugs into cells. Casein kinase 2 (CK2) is a critical protein kinase that phosphorylates >300 protein substrates and is dysregulated in a number of disease states. Among the CK2 substrates are several trans
- PMID 26580496
Japanese Journal
- Direct inhibition and down-regulation by uremic plasma components of hepatic uptake transporter for sn-38, an active metabolite of irinotecan, in humans
- Fujita Ken-ichi,Sugiura Tomoko,Okumura Hidenori,Umeda Saki,Nakamichi Noritaka,Watanabe Yusuke,Suzuki Hiromichi,Sunakawa Yu,Shimada Ken,Kawara Kaori,Sasaki Yasutsuna,Kato Yukio
- Pharmaceutical Research 31(1), 204-215, 2014-01
- … Methods: We evaluated SN-38 uptake and its inhibition by uremic toxins, 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), indoxyl sulfate (Indox), hippuric acid (HA) and indole acetate (IA), with cryopreserved human hepatocytes and HEK293 cells stably expressing hepatic uptake transporters, organic anion transporting polypeptides (OATPs). …
- NAID 120005385991
- 家入 一郎
- Organ Biology 21(2), 247-253, 2014
- … Genetic polymorphism in drug metabolizing enzymes and drug transporters has been focused on currently, especially for cytochrome P-450s (CYPs, such as CYP2C9, CYP2C19, and CYP2D6), and organic anion transporting polypeptides 1B1(OATP1B1)and pglycoprotein, respectively, are available in various clinical situations. …
- NAID 130004715813
- Characteristics of Pemetrexed Transport by Renal Basolateral Organic Anion Transporter hOAT3
- KURATA Tomohiko,IWAMOTO Takuya,KAWAHARA Yuki,OKUDA Masahiro
- Drug Metabolism and Pharmacokinetics 29(2), 148-153, 2014
- … Purpose: Pemetrexed transport by human organic anion transporters, hOAT1 (SLC22A6) and hOAT3 (SLC22A8), were characterized in comparison with methotrexate. …
- NAID 130004463362
Related Links
- Organic anion transporters were first identified in intestine, liver, and kidney based on extensive studies of membrane transport phenomena mainly of xenobiotics. Recent advances in membrane transport ... Abe, T., Kakyo, M ...
- Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn). ... Database page citation: Organic anion transporters (OATs).
★リンクテーブル★
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- 英
- organic anion transporter, OAT、organic anion transporters, OATs
- 同
- 有機アニオン輸送体
[show details]
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- 関
- organic compound、organic matter、organized、organo
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トランスポーター
- 関
- translocator、transport protein、transporter protein
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- 関
- anal、anus
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