organic anion transporter 1

出典: meddic

有機アニオン輸送体1、有機アニオントランス・ーター1

OAT1、organic anion transport protein 1

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/05/21 21:24:51」(JST)

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英文文献

  • Evaluation of transporter-mediated hepatic uptake in a non-radioactive high-throughput assay: a study of kinetics, species difference and plasma protein effect.
  • Li L, Nouraldeen A, Wilson AG.SourceDepartments of Drug Metabolism, Pharmacokinetics, Toxicology and Pathology , Lexicon Pharmaceuticals, Inc., The Woodlands, TX , USA.
  • Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.2013 Mar;43(3):253-62. doi: 10.3109/00498254.2012.713146. Epub 2012 Aug 28.
  • 1. In this manuscript we describe a non-radioactive, high-throughput method to evaluate hepatic uptake using cryopreserved hepatocytes. We have validated the uptake of pravastatin with different amounts of hepatocytes and the impact of the oil layer used in separation. The time- and concentration-
  • PMID 22928802
  • The Potential of Sutherlandia frutescens for Herb-Drug Interaction.
  • Fasinu PS, Gutmann H, Schiller H, James AD, Bouic PJ, Rosenkranz B.SourceDivision of Pharmacology, Department of Medicine, University of Stellenbosch, PO Box 19063, Tygerberg, Cape Town, 7505, South Africa. 16669967@sun.ac.za.
  • Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2013 Feb;41(2):488-97. doi: 10.1124/dmd.112.049593. Epub 2012 Dec 3.
  • In Africa, Sutherlandia frutescens is a popular medicinal herb widely consumed by people living with human immunodeficiency virus/AIDS. Concomitant use with antiretroviral drugs has generated concerns of herb-drug interaction (HDI). This study investigated the inhibitory effects of the crude extract
  • PMID 23209194
  • Analysis of the repaglinide concentration increase produced by gemfibrozil and itraconazole based on the inhibition of the hepatic uptake transporter and metabolic enzymes.
  • Kudo T, Hisaka A, Sugiyama Y, Ito K.SourceMusashino University, Research Institute of Pharmaceutical Sciences, 1-1-20 Shinmachi, Nishitokyo-shi, Tokyo 202-8585, Japan. k-ito@musashino-u.ac.jp.
  • Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2013 Feb;41(2):362-71. doi: 10.1124/dmd.112.049460. Epub 2012 Nov 8.
  • The plasma concentration of repaglinide is reported to increase greatly when given after repeated oral administration of itraconazole and gemfibrozil. The present study analyzed this interaction based on a physiologically based pharmacokinetic (PBPK) model incorporating inhibition of the hepatic upt
  • PMID 23139378

和文文献

  • プロスタグランジンと有機アニオンのトランスポーター(<特集>第66回大会シンポジウム「ビタミン・バイオファクタートランスポーター研究の最前線」)
  • Mangiferin Inhibits Renal Urate Reabsorption by Modulating Urate Transporters in Experimental Hyperuricemia
  • Mangiferin Inhibits Renal Urate Reabsorption by Modulating Urate Transporters in Experimental Hyperuricemia

関連リンク

The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. It is a member of the organic anion transporter (OAT) family of proteins. OAT1 is ...
Type I OAs are preferable substrates of members of the OAT family, which are predominantly expressed in the kidneys. Thus, in this review, we will mainly describe the OAT family. Figure 1 shows organic anion transporters such as OATs, ...

関連画像

 Organic Anion; Organic Anion Transport of Renal Organic Anion TransportersOrganic anion transporter 1Unfortunately we are unable to provide E446 | Organic Anion Transporter 1 (OAT1  of renal organic anion transporters


★リンクテーブル★
リンク元有機アニオン輸送体1」「有機アニオントランスポーター1」「OAT1」「SLC22A6
関連記事organic」「transport」「organ」「transporter」「anion

有機アニオン輸送体1」

  [★]

organic anion transporter 1、organic anion transport protein 1
有機アニオン輸送タンパク質1有機アニオントランスポーター1


有機アニオントランスポーター1」

  [★]

organic anion transporter 1、organic anion transport protein 1、OAT1
有機アニオン輸送タンパク質1有機アニオン輸送体1


OAT1」

  [★] 有機アニオントランスポーター1 organic anion transport protein 1 organic anion transporter 1

SLC22A6」

  [★]


  • organic anion transporter 1


organic」

  [★]

  • adj.
  • 有機物の、有機の、有機的な、器質性の、器質的な
organic compoundorganic matterorganizedorgano

WordNet   license wordnet

「simple and healthful and close to nature; "an organic lifestyle"」

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「a fertilizer that is derived from animal or vegetable matter」
organic fertilizer, organic fertiliser

PrepTutorEJDIC   license prepejdic

「有機体の,生物の,生物から生じた / (動植物の)器官の / 有機肥料を用いる(を用いて育った)・有機的な,組織的な,系統的な・有機質の」

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「being or relating to or derived from or having properties characteristic of living organisms; "organic life"; "organic growth"; "organic remains found in rock"」

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「involving or affecting physiology or bodily organs; "an organic disease"」

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「of or relating to foodstuff grown or raised without synthetic fertilizers or pesticides or hormones; "organic eggs"; "organic vegetables"; "organic chicken"」

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「relating or belonging to the class of chemical compounds having a carbon basis; "hydrocarbons are organic compounds"」


transport」

  [★]

  • n.
  • v.
  • 輸送する、運搬する、運ぶ
bringcarriagecarryconveydeliveryshiptraffictraffickingtransportation

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「move something or somebody around; usually over long distances」

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「an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes」

PrepTutorEJDIC   license prepejdic

「(ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機」

WordNet   license wordnet

「move while supporting, either in a vehicle or in one''s hands or on one''s body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river"」
carry

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「transport commercially」
send, ship


organ」

  [★]

  • n.
  • 臓器、器官


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「wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard」
pipe organ

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「a fully differentiated structural and functional unit in an animal that is specialized for some particular function」

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「a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"」

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「a periodical that is published by a special interest group; "the organ of the communist party"」

PrepTutorEJDIC   license prepejdic

「『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関」


transporter」

  [★] トランスポーター

translocatortransport proteintransporter protein

PrepTutorEJDIC   license prepejdic

「自動車運搬用大型トラック」

WordNet   license wordnet

「a long truck for carrying motor vehicles」
car transporter

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「a crane for moving material with dispatch as in loading and unloading ships」


anion」

  [★] アニオン

WordNet   license wordnet

「a negatively charged ion」

PrepTutorEJDIC   license prepejdic

「陰イオン」




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