WordNet

(chemistry) a substance consisting of two or more substances mixed together (not in fixed proportions and not with chemical bonding)
an alkaloid with anticholinergic effects that is used as a sedative and to treat nausea and to dilate the pupils in ophthalmic procedures; "transdermal scopolamine is used to treat motion sickness"; "someone sedated with scopolamine has difficulty lying" (同)hyoscine
natural bases containing nitrogen found in plants
an addictive narcotic extracted from seed capsules of the opium poppy

PrepTutorEJDIC

《語・句・節を対等に結んで》…『と』…,…や…,および / 《数詞を結合して》…『足す』…,…に加えて / …『しかも』…,…して,同時に… / 《時間的に》『そして』,それから,すると(and then) / 《当然の帰結として》…『ので』,…だから(and so) / 《おもに話》《命令文などの後で》『そうすれば』,そうしたら / 《追加・強調して》それに,しかも / 《対照的な内容を導いて》ところが,しかし(but) / 《譲歩的に》それなのに,それでいながら / 《A and Bで一体の関係を表して》《単数扱い》 / 《同一語を反復して多数・継続などを表して》 / 《同一の複数名詞を結合して変化・種類などを表して》 / 《話》《「形容詞+and+形容詞」の形で前の形容詞が後に副詞的に働く》 / 《話》《「動詞come, goなど+and+動詞」の形でandとその後の動詞が不定詞の働きをして》 / 《「動詞+and+動詞」の形で後の動詞が現在分詞の意を表して》 / 《話》《文頭において前の質問・意見などに同意を示して》そうとも,そして(Yes!and) / 《話》《文頭に置いて驚き・疑念・非難などを表して》ほんとうに;…なのに
〈U〉(…を)『混ぜ合わせること』,(…の)茶合《+『of』+『名』》 / 〈C〉『混合した物』,混合薬
スコポラミン(麻酔・催眠剤になる)
アルカロイド(植物に含まれる窒素を含む塩基性物質)
アヘン(阿片)ケシの種子から製造;催眠剤・鎮痛剤として使われる)

UpToDate Contents

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1. 癌疼痛のマネージメント：鎮痛補助剤（鎮痛剤） cancer pain management adjuvant analgesics coanalgesics
2. 成人における単極性うつ病および初期治療：臨床試験におけるアプローチ unipolar depression in adults and initial treatment investigational approaches
3. 慢性閉塞性肺疾患（COPD）における抗コリン療法の役割 role of anticholinergic therapy in copd
4. 小児や青年のオピオイド中毒 opioid intoxication in children and adolescents
5. オピオイド系薬剤を用いた癌疼痛のマネージメント：副作用の予防およびマネージメント cancer pain management with opioids prevention and management of side effects

English Journal

[History of opium poppy and morphine].

Norn S, Kruse PR, Kruse E.
Dansk medicinhistorisk arbog.Dan Medicinhist Arbog.2005;33:171-84.
Opium has been known for millennia to relieve pain and its use for surgical analgesia has been recorded for several centuries. The Sumerian clay tablet (about 2100 BC) is considered to be the world's oldest recorded list of medical prescriptions. It is believed by some scholars that the opium poppy
PMID 17152761

Scophedal (SEE) was it a fad or a miracle drug?

Defalque RJ1, Wright AJ.
Bulletin of anesthesia history.Bull Anesth Hist.2003 Oct;21(4):12-4.
The German firm E. Merck released in 1928, an injectable mixture of scopolamine, oxycodone, and ephedrine under the name SEE. This drug, renamed Scophedal in 1942 caused deep and prolonged analgesia, sedation, euphoria and amnesia without significant respiratory or circulatory depression. Used exten
PMID 17494237

[The morphine-scopolamine combination in chloroform anesthesia].

Vaca JM1, Herrero MA, Iglesias JL, Cabal VJ, Curto A, Gómez S.
Revista espanola de anestesiologia y reanimacion.Rev Esp Anestesiol Reanim.1992 Jul-Aug;39(4):239-45.
After introduction of surgical anesthesia with general agents such as ether and chloroform, a large number of deaths due to anesthetic toxicity were reported. With the aim to reduce toxicity several types of mixtures were devised. One of the most important was the association of opioids and scopolam
PMID 1513942